Hyperemesis Gravidarum Flashcards
When does hyperemesis start?
Week 4-7
When does hyperemesis peak?
Week 9
When does hyperemesis typically resolve by?
Week 20
What is the pathophysiology of hyperemesis?
Placenta produces B-HCG
High HCG triggers CTZ
What are the diagnostic criteria for hyperemesis?
> 5% pre-pregnancy weight loss
Dehydration
Electrolyte imbalances
What is used to assess the severity of hyperemesis?
PUQE score
pregnancy unique quantification of emesis
How is hyperemesis investigated?
Weight
Urine dip - look for ketones
Bloods
- FBC
- U+Es
- glucose
- LFTs
How is mild hyperemesis managed?
Oral rehydration
Anti-emetics
What are the anti-emetics of choice for hyperemesis?
Chlorpromazine
Cyclizine
Ondansetron
Metoclopramide
How is moderate/severe hyperemesis managed?
IV fluids
IV anti-emetics
IV thiamine