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Path. > Path. 5/5/15 > Flashcards

Path. 5/5/15 Flashcards

1
Q

Lumphangitis

A

Inflammation of lymph vessels

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2
Q

Lymphadenitis

A

(Aden-means tissue) dramatic enlargement (inflammation) of the lymphatic node.
* pain here is good, means that there is no cancer.

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3
Q

Bacteremia

A

Presence of bacteria in the circulation.

*bad! Dangerous for the rest of ones life!

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4
Q

Leukocytosis

A

(More than 9,000 leukocytes per 1 cub. mm)
Increase amount of white blood cells
Predominately neutrophils

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5
Q

White blood cells

A 
Neutrophils 55– 60%
Lymphocytes 20– 25%
Monocytes 4–8%
Eosinophils 2–4%
Basophils 0.5–1%
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6
Q

Neutrophilia

A

Acute bacterial infection

Short lifespan

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7
Q

Lymphocytosis

A

Increase of lymphocytes

Due to viral infection

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8
Q

Eosinophilia

A

Allergic reaction
parasitic infection
Contains antihistamine substance

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9
Q

Monocytosis

A

Increase of monocytes
Chronic bacterial infection
Long lifespan

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10
Q

Kinin cascade

A 
Hageman factor (clotting factor)-> prekallikrein->kallikrein->kininogen->Brady Kinin 
Bradykinin accounts for pain, very unstable, undergoes destruction after five minutes by Kinin
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11
Q

Antibodies

A

Only plasma derived mediators that is not from cascade

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12
Q

Duration

chronic inflammation

A

Last more than six weeks

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13
Q

Character of exudate

Chronic inflammation

A

Always develops acute inflammation. Last 7 to 10 days and disappears.

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14
Q

Cell content

Chronic inflammation

A

Cells that immigrate into acute inflammation such as neutrophils and monocytes/macrophages.
Neutrophils last 2 to 3 days die faster and acute inflammation
Only monocytes are found in chronic inflammation
Lymphocytes are always there and chronic inflammation

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15
Q

Selected agents typically involved and chronic inflammation

A 
Mycobacterium tuberculosis -> tuberculosis
Mycobacterium leprae -> leprosy
Listeria species -> listeriosis
Treponema pallidium -> syphilis
Brucella species -> brucellosis
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16
Q

Pneumoconiosis

A

Coal workers lungs
if patient inhales small particles of silica (stone)
Results in silicotic nodules- formation of a connected tissues (scar tissue)

17
Q

Juvenile rheumatoid arthritis

A

Swollen joints, very painful, this is a very bad part of inflammation. Develops when there is no need for inflammation

18
Q

Aseptic osteonecrosis

A

No blood can flow to the femur head or neck due to lack of blood supply

19
Q

Chronic glomerulonephritis

A

Inflammation of the kidneys, small granulated kidneys, replace with scar tissue

20
Q

Chronic inflammation arises in the following settings:

A

Viral infection
Persistent microbial infection
Prolonged exposure to potentially toxic agents
Autoimmune diseases

21
Q

Chronic inflammation

A

Nonspecific chronic inflammation

Granulomatous inflammation

22
Q

Granulomatous inflammation

A

Very specific
Accumulation of granuloma
Example tuberculosis

23
Q

Multi nucleated giant cells

A

Coalescence of epithelial cells

24
Q

Healing

A

A process of replacement of lost tissue, restoration of its structure, strength, and sometimes function

25
Q

Parenchyma

A

Functional tissue

26
Q

Stroma

A

Connected tissue, everywhere the same

27
Q

Regeneration

A

The healing process, when tissue is replaced from parenchyma

28
Q

Repair

A

The healing process of laying down fibrous connective tissue to restore strength and structural integrity of damaged tissue that cannot regenerate

29
Q

Labile tissue

A

Divide continually to replace cells that are constantly being depleted by normal process
1.5%

30
Q

Stable tissue

A

Cells do not normally divide beyond adolescence, when normal development is complete
Less than 1.5%

31
Q

Permanent tissue

A

One which loses all mitotic activity soon after birth and never to regain it

32
Q

Pathway of lymph

A

Lymphs->thoracic ducts->jugular vein->lymph appears in the blood.

Path. (18 decks)

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