Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

S.N Immunology I > Past papers > Flashcards

Past papers Flashcards

1
Q

The MHC Ag are

A

Plasma membrane glycoproteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Extravasation of lymphocytes is helped by

A

Diverse adhesive proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

They are professional phagocytes, except

MPH
Neutrophils
Basophils
Monocytes

A

Basophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Ig-a chain is found on heavy chain of Ig__

A

IgA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Complement genes in the MHC III region

A

C2
C4
B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Myeloperoxidase is most commonly epressed on

A

Neutrophil granulocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

____ have an essential role in processing of endogenous Ag

A

Proteasomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

__ is involved in mast cell and basophil degranulation

A

C3a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Progenito cell for monocytes

A

Myeloid cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

PRR do not identify

A

Unmethylated sequences

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CD Ag are

A

Differentiation Ag

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Homing receptors are present on the surface of

A

Lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

TNF-a is located on gene ___

A

MHC III

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

CD4 chain binds to _____ of MHC2

A

Constant chain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cells having IL6 receptors before inflammation

A

Liver cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Defensins in structure are

A

Cyclic peptides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Conc. of Albumin in acute phase reaction

A

Decreased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

High affinity Fc epsilone receptor are found on

A

Basophil granulocytes and mast cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Size of TCR repertoire is

A

Super big

More then a billion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Both Ig and TCR are characterized by

A

Domain like globular structure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Number of hypervariable regions in Ig and TCR is

A

3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Secondary innume response has

A

Shorter latency and higher amplitude

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Adhesive proteins play a part in

A

Majority of cell to cell interactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Chemotactic substance of bacterial origin

A

LPS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

IC bacterias are mediated mostly by

A

Activated MPH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Autoimmune disease are enhanced by

A

Estrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Which of TCR chains are hypervariable

A

a, b, gamma, delta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

A receptor that doesnt play a role in endocytosis or phagocytosis

A

TCR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

PAMP-PRR intercation induce

A

IL1
IL8
TNF a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

When do naive T cells enter the lymph nodes?

A

Anytime, through the HEV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

RAG enzymes are present in

A

Bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Who has c-kit on its surface

A

Pluripotent HSC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Main biological function of IL2 on T cells

A

GF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Major costimulatory factor on APC

A

B7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Inheritance of MHC alleles is

A

Codominant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Major costimulatory factor on T cell

A

CD28

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Cytokines are not

A

Ag specific

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

IL which inhibits cellular immune response

A

IL4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

___ is most likely to promote acute Neut. inflammatory response

A

Th17

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

IL6 role in B cell maturation

A

Terminal differentiation of B cell matures to plasma cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Class switch in B cell activation is regulated by

A

Helper T cell cytokines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Th1-like cytokines are produced by

A

NK cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Onvariant gamma chain has its role in

A

Processing of exogenous Ag

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

IFN of Th1

A

IFN gamma

45
Q

Most important role of IL2

A

Induces B cell differentiation

46
Q

Number of thymocytes during maturation

Increase/Decrease

A

Decrease

47
Q

Mutual inhibition is by

A

UFN-gamma and IL4

48
Q

Affinity maturation happens in

A

Periphery

49
Q

CD__ has IgE binding capacity

A

CD23

50
Q

Type of cells produced in Bone marrow

A

Every myeloid and lymphoid cell types

51
Q

CXC chemokines are produced by

A

Lymphocytes

52
Q

Changes during isotype switch

A

Constant regions of heavy chain

53
Q

The Ag binding part of a Bcell determines his

A

Idiotype

54
Q

IL23 induces

A

Th17

55
Q

Mononuclear phagocytosis includes which cell

A

Kupffer cell

56
Q

Where can we find double negative T cells?

A

Subcapsular area of the thymus

57
Q

Which mediator can lead to systemic inflammation

IFN-a
IFN-gamma
TNF-a

A

TNF-a

58
Q

Hybridomas are made from combining

A

B cell and myeloma cell

59
Q

Which process cannot be activated by complement system?

A

Ab production

60
Q

Light chain of BCR

A

Lambda

61
Q

Light chain of Ab is made of

A

V
J
1 or 2 possible different constant region

62
Q

Marker of T cell activation

A

IL2-R

63
Q

Intgein structure

A

Heterodimers

64
Q

Do NK cells express FC epsilon receptor?

A

No

65
Q

WHich cell produces many IFN-gamma?

A

Th1

66
Q

Start and end point of TAP

A

Golgi-cytoplasm

67
Q

CD1 presents

A

LIpids

68
Q

Negative acute phase proteins

A

Albumin
Transferrin
Antithrombin

69
Q

Which R cannot be an opsonizing R?

FcR
CR
Lectin R
PRR

A

PRR

70
Q

Which psychiatric disease preasents with symptoms symilar to those seen inInflammation and immune activation?

A

Depression

71
Q

CD34=

A

HSC progenitor marker

72
Q

Main co-stimulatory in B cell activation

A

CD40-CD40L

73
Q

Paracortical region of lymph nodes contains ,ainly

A

T cells

74
Q

Alternative pathway activation can be measured by

A

Erythrolysis

75
Q

Edema in HAE is due to

A

Bradikinin

76
Q

M spike is common in which disease

A

Multiple myeloma

77
Q

Which of these cells have no signaling function in inflammation?

B lymphocytes
Keratinocytes
MPH
Fibroblasts

A

B lymphocytes

78
Q

Natural Ab are:

A

Low affinity, cross-reacting autoAb

79
Q

Receptor for HIV is

A

CD4

80
Q

___ denatures proteins during Western-blot

A

SDS

81
Q

Which one is a chemoattractant for “homing”

IL8
IL1
IL6

A

IL1

82
Q

Where do B cells go through somatic hypermutation

A

Periphery

83
Q

Which cytokine is responsible for class switching to IgA?

A

TGF-beta

beta is ending with a

84
Q

__ and _____ secrete IL4

A

Th2

Mast cells

85
Q 
Which makes covalent bond in complement activation? C1
C2
Crq
C4
C5
A

Crq

86
Q

Invarians chain action

A

Inhibition of MHC II

87
Q

HSN II is medited by which Ab

A

IgG

88
Q

CD23=

A

Receptor for IgE

89
Q

Immunological homunculus=

A

Obligate reaction of the immune system to dominant Ag

90
Q

Which cytokines promotes angiogenesis around the tumor?

A

TGF-beta

אנגגגיוגגגנסיס

91
Q

Decrease MHC expression can cause

A

Tumor escape

92
Q

Defensins are

A

Peptides

93
Q

Which cells dominate in the follicles of lymph nodes?

A

B cells

94
Q

FSC=

A

Forward Scatter

95
Q

FSC measures

A

cell size

96
Q

SCC=

A

Side Scatter

97
Q

SCC measures

A

Internak complexability

98
Q

Cross presentation occurs when ___ cells present ___ Ag on MHC1 molecules to elict ___ T cell response against viral tumor Ag

A

Cross presentation occurs when APC cells present exogenous Ag on MHC1 molecules to elict CD8+ T cell response against viral tumor Ag

99
Q

Which lympholid cells do not express Ag binding receptors

A

NK

100
Q

Is the liver a hematopoietic organ?

A

Only in the embryo

101
Q

Ig super family membares (give 5)

A 
MHC1, MHC2
CD4
CD8
CD28
TCR
BCR
102
Q

CD28 is expressed on

A

T cells

co-stimulation with B7

103
Q

Against which pathogenes does the complement system protect?

A

Bacteria
Fungi
Protozoa

104
Q

Steps of inflammatory extravasation (5)

A 
Attachment
Rolling
Activation
Adhesion
Migration
105
Q

Handaling of exogenous Ag before presenting them on the MHC2 is done where?

A

Endosome/Lysosome

106
Q

Serum sickness is type __ HSN

A

III

107
Q

Serum sickness causative agent

A

Mediacation (Penicillin)

Passive immunization

108
Q

SLE causative agent

A

Genetic

Enviormental

S.N Immunology I (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions