Parvoviral Enteritis Flashcards
What viral agents causes parvo?
Canine Parvovirus 2 (CPV2)
Explain why CPV2 is hard to destroy
b/c it doesn’t have an envelope
How is parvo shed?
in feces
How is parvo transmitted
fecal-oral/nasal route
6 breeds at a higher risk for parvo
Rottweiler Doberman pinscher Labrador retriever American Staffordshire Terrier German shepherd Artic breeds (Siberian husky, Alaskan malamute, Norwegian elkhound)
How does parvo act on the villi of the intestine?
- Virus infects the intestinal crypts of the epithelial cells where new enterocytes are made.
- This interferes with normal epithelial cell growth and development because the new enterocytes will not be efficiently or effectively made.
- Villi will be shortened
How does shortened villi lead to clinical signs?
Shorter villi are unable to maintain their absorptive capabilities which compromises absorptive function of the SI.
What does parvo do to WBCs?
destroys precursors of lymphocytes and lymphoid cells
Describe the changes that may occur in the CBC as a result of lymphocyte and lymphoid cell destruction.
- Circulating lymphopenia and neutropenia
- Significant leukopenia
4 Complicating disorders that may occur with parvo
- Sepsis
- Aspriation Pneumonia
- Intussusception
- Supportive Polyarthritis
What leads to sepsis in parvo patients?
- Destruction of intestinal mucosal integrity may allow for trasmigration of normal intestinal bacteria into systemic circulation
- The patient is often leukopenic, meaning they won’t have the defenses to control bacterial spread
- Result = severe systemic bacterial infection (sepsis)
What leads to aspiration pneumonia in parvo patients?
- Severe depression may result in a swallow reflex that is NOT in tact
- No swallow reflex means the very acidic GI content can be aspirated into the lungs
- Acidic contents in lungs causes severe inflammation of lung tissue (chemical pneumonia)
- Bacterial pneumonia is also possible if bacteria is in aspirated contents
What leads to intussusception in parvo patients?
- Increased intestinal motility in the intestines due to viral damage of the intestines
- Increased motility may result in SI telescoping in on itself
- Creates a section of intestinal tissue that is no longer effective
What leads to suppurative polyarthritis in parvo patients, and when does it often occur?
- Occurs several days to weeks post recovery from initial infection
- Viral and bacterial particles lodge themselves into small hairpin capillaries located in the joints
- This results in inflammation accompanied with bacterial infection of the joints
Nursing Intervention: GI Rest
- describe
- pathology it reverses
- Designed to allow intestinal tract to rest and begin healing process by growing new epithelial cells
- NPO until no V for 24hrs
- Followed by reintroduction of water, then very small amounts of highly palatable food until daily requirement is being fed over 2-3 feedings