Epilepsy Flashcards

1
Q

Define idiopathic

A

“that idiot doctor can’t figure out why it’s happening”

no evidence of an underlying cause; can only be used after ruling out all potential other causes through Hx, PE, and diagnostic testing

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2
Q

Define seizure

A

a single episode consisting of paroxysmal transient disturbances of the brain function that may be manifested as episodic impairment of loss of consciousness, abnormal motor phenomena, and sensory disturbances

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3
Q

Define epilepsy

A

a combination of different seizure episodes

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4
Q

Define status epilepticus

A

continuous ongoing seizures

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5
Q

Symptomatic vs idiopathic epilepsy

A

symptomatic epilepsy has an identifiable cause, but idiopathic does not; idiopathic is the more common of the two in dogs

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6
Q

What happens in the brain during a partial seizure

A

one neuron (or a small group of focal neurons) is stimulated to discharge electrical impulses; the electrical activity remains within this small group of neourns

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7
Q

What happens in the brain when a generalized seizure occurs?

A

the electrical activity from one neuron/a group of focal neurons spreads throughout the rest of the cerebral hemisphere

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8
Q

List and describe the 3 phases of a seizure

A
  1. Pre-ictal –> period of time immediately prior to ictus where the patient may be nervous or pace
  2. Ictus –> period of actual seizure activity that can last 2-3mins
  3. Post-ictal –> a time period post seizure where pet may be tired, lethargic, confused, ravenous or anorexic; lasts a few hours up to a day
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9
Q

What is the typical presenting signalment and Hx of a patient with idiopathic epilepsy?

A

young to middle age dog (1-5yr old) that otherwise appears healthy upon PE; O may describe P as not being “quite right” because O missed the seizure but notices the post-ictal phase

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10
Q

4 Important questions to ask when a patient presents during or after a seizure

A
  1. Can you describe the nature of the event?
  2. Is this a first time event for this patient?
  3. Was there any potential expsoure to anything unordinary?
  4. Was there any exposure to anything considered “normal” or “safe”?
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11
Q

General characteristics of generalized seizures

A
  • loss of consciousness
  • loss of bladder/bowel control
  • tonic-clonic movements
  • jaw snapping
  • post-ictal phase may be short or long in duration
  • seizure usually lasts 1-3min
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12
Q

General characteristics of syncope (fainting)

A
  • loss of consciousness
  • can lose bladder/bowel control
  • may paddle trying to rise
  • usually no rhythmic tonic/clonic movements
  • may be slightly disoriented post syncopal episode; usually short duration
  • event lasts <1min
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13
Q

List 4 things that can be done as an RVT when a patient presents during a seizure

A
  1. Take patient to the back and direct client to a quite room (with another staff member to gather more info if possible)
  2. Take TPR after making sure a DVM knows a seizing patient has arrived
  3. Place IV catheter if enough hands are available
  4. Gather a blood sample for serum blood glucose (and PCV/TP/BUN if enough blood obtained)
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14
Q

When should cooling methods be initiated on a seizure patient?

A

if temp >104

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15
Q

List 2 ways to administer diazepam to an active seizing patient.

A
  1. Per rectum via syringe without needle or red rubber catheter
  2. IV only if an IV cath has already been placed
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16
Q

What happens if Diazepam is given extravascularly?

A

Nothing truly bad happens, but it doesn’t act nearly as fast as per rectum or direct IV

17
Q

Aside from a PE, list 4 non-invasive diagnostic tests that can be performed to evaluate a patient that has had a seizure

A

CBC
Serum chemistry
UA
Fasting & post-prandial bile acids

18
Q

List 3 more invasive diagnostic tests that can be done to evaluate a patient that has has a seizure

A

Cerebrospinal fluid (CFS) tap
CT
MRI

19
Q

What is a seizure diary and what should go in it?

A

a place to document info regarding seizures

  • date, time, and length of each episode
  • unusual behavior or occurrences that may indicate a pre-ictal period of a trigger for the seizure
  • medication administration
20
Q

When is a patient considered a candidate for medical therapy of epilepsy?

A

when it has multiple seizure episodes hours, days, weeks, or months apart

21
Q

What is “steady state level” as it pertains to anticonvulsant meds?

A

when the drug has finally reached a constant level in the blood

22
Q

Why is steady state important/what happens if it gets disrupted?

A

-You can’t draw blood to check levels until after the steady state has been reached because you won’t get an accurate answer; if the medication is not given correctly steady state will not be achieved making bloodwork results inaccurate

23
Q

What are the two common oral anticonvulsants meds used in dogs with idiopathic epilepsy

A

Phenobarbital

KBr