Part I: Lecture 26

Question 1

main question to explain pedigree chart

Answer 1

can we put in A and a alleles for an inheritance pattern?

Question 2

probability that is ___ inheritance: high - answer to main question

Answer 2

yes

Question 3

probability that is ___ inheritance: low - answer to main question

Answer 3

yes but unlikely in some way

Question 4

probability that is ___ inheritance: impossible- answer to main question

Answer 4

no

Question 5

pedigree charts work with ____ diseases

Answer 5

some/single gene

Question 6

diseases that work with pedigree charts

Answer 6

single gene disorders
inherited mutation
complete penetrance

Question 7

coronary artery disease is the result of ____

Answer 7

mutations in several genes + lifestyle choices

Question 8

diseases that don’t work with pedigree charts

Answer 8

-multigene disorders
-germline mutations (unaffected parents but affected child)
-incomplete penetrance

Question 9

penetrance (def.)

Answer 9

likely hood that someone who has the mutation also has the disease

Question 10

complete penetrance (def.)

Answer 10

has the mutation, has the disease

Question 11

incomplete penetrance (def.)

Answer 11

has the mutation, does not have the disease