Part F: Lecture 40

Question 1

RBC have ____ and ___ in their membrane

Answer 1

glycoproteins and glycolipids

Question 2

_____ are removed from donated blood before transfusions

Answer 2

WBC

Question 3

ABO blood group is made from ___

Answer 3

glycolipids and glycoproteins

Question 4

ABO gene is on which chromosome?

Answer 4

9q34 (autosome)

Question 4

ABO expressed in ___

Answer 4

immature RBCs

Question 5

ABO encodes for ___

Answer 5

a sugar modifying enzyme

Question 6

antigen for Type O blood

Answer 6

H-antigen

Question 7

antigens for Type A blood

Answer 7

A-antigen, H-antigen

Question 8

antigens for Type B blood

Answer 8

B-antigen, H-antigen

Question 9

antigens for Type AB blood

Answer 9

A-antigen, B-antigen, H-antigen

Question 10

genotype for Type O blood

Answer 10

i/i

Question 11

genotype for Type A blood

Answer 11

I(A)/I(A) , I(A)/I(i)

Question 12

genotype for Type B blood

Answer 12

I(B)/I(B) , I(B)/I(i)

Question 13

genotype for Type AB blood

Answer 13

I(A)/I(B)

Question 14

everyone has ____antigens for blood

Answer 14

H

Question 15

I(A)/I(B) allele interaction

Answer 15

codominance

Question 16

I(A)/I(i) allele interaction

Answer 16

complete dominance

Question 17

Genotype: D/ ___

Answer 17

D-antigen present
Rh+

Question 18

Genotype: d/d

Answer 18

D-antigen absent
Rh-

Question 19

Relevance of Rh genotype

Answer 19

must prevent mom’s (Rh-) immune system from attacking fetal Rh+ RBCs

Question 20

MN blood group

Answer 20

two alleles (M and N)
very similar alleles -> doesn’t matter for blood donations

Question 21

Current testing for blood type

Answer 21

antibodies agglutinate (clump together) RBCs if the antigen are present

Question 22

blood type + donor determination

Answer 22

ABO group ✔
Rh+ vs Rh- ✔
MN (x)