P2Y-12 I Flashcards
1
Q
Examples
A
- Clopidogrel, ticagrelor, prasugrel
2
Q
Mechanism
A
- Targets ADP receptor on platelets -> Inhibit platelet aggregation
3
Q
Indications
A
- ACS, Secondary prevention thrombotic
4
Q
SE
A
Common: GI disturbance, bleeding disorders
Important: Peptic ulcer
5
Q
CI
A
- Hepatic & renal impairment
- Pregnancy/breast-feeding