Morphine/codeine Flashcards
1
Q
Class
A
- Opiate
2
Q
SE
A
Common: Constipation, n/v, ureteric spasm
Important: Resp depression(‘Kop’ receptors), Hypotension (vasodilation), addiction, coma
3
Q
Tx of overdose
A
Naloxone
4
Q
CI
A
Obstructive bowel disorders, prostatic hypertrophy, shock, ARDS, renal impairment
5
Q
Mechanism
A
- Bind to opioid ‘mu’ receptors in CNS Hyperpolarise neuron -> Inhibit asc./desc. pain signals
