Cyclophosphamide Flashcards
1
Q
Class
A
- Immunosuppressant & chemotherapy
2
Q
Mechanism
A
- Alkylates DNA bases -> form cross links -> Unable to split in DNA replication
3
Q
Indications
A
- Chemotherapy (lymphoma, MM)
4
Q
SE
A
Common: Myelosuppression - Agranulocytosis, anaemia
Important:
5
Q
CI
A
- Hypersensitivity, pregnancy