(P) Week 4: WBC Functions and Kinetics Part 3

Question 1

What does the T dependent B cell need to be activated?

Answer 1

stimuli in the form of presented antigen

Question 2

A stimuli for T independent B cell

bacteria with lipopolysaccharide content

Answer 2

B-cell mitogen

Question 3

__________ is also known as antigenic determinant site

Answer 3

epitope

Question 4

Antigen known as ___________ which are
comprising of lipopolysaccharides or repetitive
epitopes or repetitive antigenic determinant sites
of a polysaccharide

Answer 4

mitogen

Question 5

C3d and C3b are ________________ are stuck to bacteria, which stimulates the activation of the B cell

Answer 5

complement fragments

Question 6

B cells are immunoglobulin markers and __________ which enables it to bind to either C3d or C3b (complement fragments)

Answer 6

complement receptor

Question 7

Complimentary receptor ___ binds with C3d
Complimentary receptor ___ binds with C3b

Answer 7

II
I

Question 8

the five different classes of immunoglobulins are differentiated through what

Answer 8

c regions

Question 9

what type of structure is observed in immunoglobulin proteins?

Answer 9

y structure

Question 10

Two types of immunoglobulin chains

Answer 10

heavy chain
light chain

Question 11

antibody region where the amino acid component is constant

Answer 11

constant region

Question 12

antibody region where it binds to different types of antigens aka “antigen-binding site”

Answer 12

variable region

Question 13

The tail of the constant region

Answer 13

FC region / fragment

Question 14

Two fragments of the antibody

_________ - fragment of antigen binding
__________- fragment of crystallizable fragment

Answer 14

FAB
FC

Question 15

most effective type of antibody, lasts long in our plasma

Answer 15

IgG

Question 16

antibody for primary immune response

Answer 16

IgM

Question 17

antibody seen on body secretions or body fluids

Answer 17

IgA

Question 18

a process of enhancing the
phagocytic power of the phagocytes in the presence
of opsonin

Answer 18

opsonization

Question 19

The classical pathway is in the ____ line of defense, in the adaptive immunity

Answer 19

third

Question 20

T or F

The alternative and lectin pathway are part of the adaptive immunity

Answer 20

f (natural immunity)

Question 21

The classical pathway needs _______ that is bounded to a bacteria

Answer 21

antibody

Question 22

the T cytotoxic cell recognizes _______ that enters the cell

Answer 22

viruses

Question 23

In T cytotoxic cells, _____ binds with ________ to destroy virally infected cells

Answer 23

CD8+ binds with MHC type I

Question 24

produces or releases apoptotic
properties or apoptotic chemicals such as
granzyme, perforin, and granulysin

this then destroys the virus that was detected

Answer 24

CD8+

Question 25

What do NK cells recognize instead of antigens?

Answer 25

MHC molecules

Question 26

what are the two stress associated molecules

Answer 26

MICA MICB

Question 27

- major histocompatibility complex 1 or MHC type 1 sequential protein A and sequential protein B

Answer 27

MICA and MICB

Question 28

what are the receptors of the NK cell

Answer 28

NKG2D, NKp44, NKp46, NKp30

Question 29

________ are very effective in killing viral infected or cancer cells. Our first line of defense against cancer and viruses

Answer 29

NK cells

Question 30

what CD marker is needed in the antibody dependent cellular toxicity

Answer 30

CD16

Question 31

what activates the cell in the antibody dependent cellular cytotoxicity

Answer 31

Syk / tyrosine kinase

Question 32

Neutrophils and monocytes are direct descendants of a common progenitor known as:

Answer 32

GMP

Question 33

The stage in neutrophilic development in which the nucleus is indented in a kidney bean shape and the cytoplasm has secondary granules that are lavender in color is the:

Answer 33

Metamyelocyte

Question 34

Type II myeloblasts are characterized by: a. The presence of fewer than 20 primary granules per cell b. Basophilic cytoplasm with many secondary granules c. The absence of granules

Answer 34

a

Question 35

Which one of the following is a function of neutrophils? a. Presentation of antigen to T and B lymphocytes b. Protection against re exposure by same antigen c. Nonspecific destruction of foreign organisms d. Initiation of delayed hypersensitivity response

Answer 35

c

Question 36

Which of the following cells are important in immune regulation, allergic inflammation, and destruction of tissue invading helminths? a. Neutrophils and monocytes b. Eosinophils and basophils c. T and B lymphocytes d. Macrophages and dendritic cells

Answer 36

b

Question 37

Basophils and mast cells have high-affinity surface receptors for which immunoglobulin? a. A b. D c. E d. G

Answer 37

c

Question 38

Which of the following cell types is capable of differentiating into osteoclasts, macrophages, or dendritic cells? a. Neutrophils b. Lymphocytes c. Monocytes d. Eosinophils

Answer 38

c

Question 39

Macrophages aid in adaptive immunity by: a. Degrading antigen and presenting it to lymphocytes b. Ingesting and digesting organisms that neutrophils cannot c. Synthesizing complement components d. Storing iron from senescent red cells

Answer 39

a

Question 40

Which of the following is the final stage of B cell maturation after activation by antigen? a. Large, granular lymphocyte b. Plasma cell c. Reactive lymphocyte d. Immunoblast

Answer 40

b

Question 41

The following is unique to both B and T lymphocytes and occurs during their early development: a. Expression of surface antigens CD4 and CD8 b. Maturation in the thymus c. Synthesis of immunoglobulins d. Rearrangement of antigen receptor genes

Answer 41

d