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Hematology 1 > F(4) CD markers > Flashcards

F(4) CD markers Flashcards

1
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD 34

A

a

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1
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD 117

A

a

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2
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

Terminal Deoxynucleotidyl transferase

A

a

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3
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD 33

A

B

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4
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD 13

A

B

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5
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD 15

A

B

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6
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD14

A

B

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7
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD71

A

C

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8
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

Glycophorin A

A

C

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9
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD41

A

D

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10
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD42

A

D

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11
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD61

A

D

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12
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD19

A

e

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13
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD 20

A

B

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14
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD22

A

E

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15
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

K light chain

A

E

16
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

Lambda light chin

A

E

17
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD2

A

F

18
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD3

A

F

19
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD4

A

F

20
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD5

A

F

21
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD7

A

F

22
Q

match the marker to the lineage

a. immature
b. granulocyte / monocyte
c. erythroid
d. megakaryocyte
e. B lymphocyte
f. T lymphocyte

CD8

A

F

23
Q

What are the CD markers under the immature lineage

A

CD34
CD117
Terminal deoxynuleotidyl transferase

24
Q

What are the CD markers under the granulocyte / monocyte lineage

A

CD 33
CD 13
CD 15
CD 14

25
Q

What are the CD markers under the Erythroid lineage

A

CD 71
Glycophorin A

26
Q

What are the CD markers under the Megakaryocye lineage

A

CD 41
CD 42
CD 61

27
Q

What are the CD markers under the B lymphocyte lineage

A

CD 19
CD 20
CD 22
K light chain
Lambda light chain

28
Q

What are the CD markers under the T lymphocyte lineage

A

CD 2
CD 3
CD 4
CD 5
CD 7
CD 8

29
Q

CELL POPULATION IDENTIFIED BY FLOW CYTOMETRY

Negative for CD45
CD71 transferrin receptor (low in reticulocyte)
Glycophorin A

A

Erythroid lineage

30
Q

CELL POPULATION IDENTIFIED BY FLOW CYTOMETRY

CD41 and CD61 (gpIIb / IIIa) - first marker of megakaryocytes differentiation
CD34 31,36 present in Megakaryoblast
CD42, 62p, and 36 present in platelets and Megakaryocyte

A

Megakaryocytic lineage

31
Q
  • CD34, terminal deoxynucleotidyl transferase (Tdt) present both in T cell and B cell
  • CD19, cytoplasmic CD22 and
  • CD79 earliest B cell marker
  • CD10 is acquired as B cell
  • precursor matures but declines as B cell reaches full maturation
  • U chain immature B cell marker
  • CD 20 marker of mature B cell
  • Kappa and lambda chain marker of mature B cell
  • CD34, terminal deoxynucleotidyl transferase (Tdt) present both in T cell and B cell
  • CD2, 7, cytoplasmic CD 3 marker of immature T cell
  • CD2 ,7 and 56 is present in NK cell
  • As T cell matures CD1a and CD 5 and co expression of CD4 and 8 appeared
  • Finally CD 3 appears with subsequent loss of CD 4 and 8
A

Lymphoid lineage

Hematology 1 (31 decks)

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