Overview of the lymphatics system Flashcards

1
Q

What is the lymphatics system?

A

Fluid conducting system

Transports lymph in vessels connected by nodes

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2
Q

What is lymph?

A

Clear, watery fluid made from reabsorbed interstitial fluid

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3
Q

Function of the lymph

A

Drains excess interstitial fluid to maintain circulating volume and blood pressure
Transports dietary lipids and lipid soluble vitamins
Immune response

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4
Q

Where are lymphatic capillaries found?

A

Everywhere except avascular tissue, CNS, spleen and bone marrow

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5
Q

Where are lacteals found?

A

Small intestine

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6
Q

What do lacteals do?

A

Carry dietary lipids to lymphatic vessels

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7
Q

What do anchoring filaments do?

A

Attach lymphatic endothelial cells to surrounding tissues. When pressure rises, the cells separate so fluid can pass through

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8
Q

Characteristics of lymphatic capillaries

A
Has both lymphatic and venous component
Drain fluid outside cells 
Endothelium opens so fluid can permeate
Located between cells, one end is open
Overlap to ensure one way flow of lymph
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9
Q

Flow chart passage of lymph

A

Lymph capillary - lymph vessel - lymph node - lymph trunks - lymph disks

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10
Q

What are the two pumps that help move lymph?

A

Skeletal muscle pump and respiratory pump

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11
Q

How does the skeletal muscle pump help move lymph?

A

Milking action caused by skeletal muscle contractions

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12
Q

How does the respiratory pump help move lymph?

A

In inhalation, lymph travels down pressure gradient from abdomen to chest

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13
Q

What are the five lymph trunks?

A
Jugular
Subclavian
Bronchomediastinal 
Intestinal
Lumbar
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14
Q

Where are the jugular lymph trunks located?

A

Head and neck

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15
Q

Where are the subclavian lymph trunks located?

A

Upper limbs

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16
Q

Where are the bronchomediastinal lymph trunks located?

A

Thoracic wall, lung and heart

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17
Q

Where are the intestinal lymph trunks located?

A

Liver, stomach, intestine, pancreas

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18
Q

Where are the lumbar lymph trunks located?

A

Lower limbs, pelvis, kidneys, adrenal glands, abdominal wall

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19
Q

How long is the thoracic duct?

A

40 cm

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20
Q

What does the thoracic duct originate as?

A

Dilation cisternachyli

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21
Q

Where does the thoracic duct receive lymph from?

A

Lower limbs, lumbar trunks, intestine, left jugular, left subclavian, left bronchiomediastinal

22
Q

Where does the thoracic duct drain lymph from?

A

Right jugular, right subclavian, right bronchiomediastinal

23
Q

How long is the right lymphatic duct?

A

1.2 cm

24
Q

When are the right lymphatic duct and left thoracic duct commonly injured?

A

Neck dissections to remove cancerous lymph nodes

25
Q

What are venous angles?

A

Site of drainage of lymphatic ducts

Junction of internal jugular vein and subclavian vein bilaterally

26
Q

What are primary lymphatic organs?

A

Sites where stem cells divide and become immunocompetent

27
Q

Where do stem cells come from?

A

Red bone marrow

28
Q

What are the two primary lymphatic organs?

A

Bone marrow and thymus

29
Q

What are secondary lymphatic organs?

A

Where immune response happens - they house lymphocytes

30
Q

Where are Peyer’s patches found?

A

Intestine

31
Q

What are the secondary lymphatic organs?

A

Lymph nodes, spleen, lymph nodules

32
Q

What does MALT stand for?

A

Mucosa Associated Lymphatic Tissue

Adenoids in phalangeal tract

33
Q

What shape are lymph nodes?

A

Kidney

34
Q

What do lymph nodes do?

A

Filter lymph as it enters

They trap particles with fibres

35
Q

Where are lymph nodes found?

A

Throughout the body, can be superficial and deep

36
Q

How does waste leave the lymph nodes?

A

Efferent vessels

37
Q

Why does lymph only flow in one direction through the lymph nodes?

A

Valves

38
Q

What does the thymus processing organ do?

A

Makes T cells immunocompetent

39
Q

Where do B cells develop and mature?

A

Bone marrow

40
Q

Where do T cells develop?

A

Bone marrow

41
Q

Where do T-cells mature?

A

Thymus

42
Q

Characteristics of spleen

A

Red and white pulp
Left hypochondrium
Secondary lymph organ

43
Q

Functions of spleen

A

Immune response, degrade and store RBCs, store platelets, haematopoeisis in fetus

44
Q

What are adenoids?

A

Nasopharyngeal tonsils

45
Q

Where are adenoids located?

A

Behind nose, posterior opening of nasal cavity, roof of posterior wall of pharynx

46
Q

What is filariasis?

A

Soft tissue full of blocked lymphatic tissue

47
Q

What are Peyer’s patches?

A

Aggregated lymphatic follicles

48
Q

How much fluid does the lymphatic system return to the body each day?

A

3 litres

49
Q

How can lymph vessels be blocked?

A

Infection and fibrosis - microfilaria Bancrofti

50
Q

Life cycle of microfilaria bancrofti?

A

Microfilaria enter the mosquito
Develop into infected larvae
Injected into new host
Mature into worms and spread throughout lymphatic system