Other Blood Grou Flashcards
1
Q
The popular ag in kell grouo are
A
k ag and K ag
2
Q
kel 1
A
K Kell
3
Q
Kell 3
A
Kpa penny
4
Q
Kell 6
A
Jsa sutter
5
Q
Kell 4
A
Kpb rautenberg
6
Q
Kell 2
A
k cellano
7
Q
Kell 7
A
Jsb matthews
8
Q
This is immunogenic and exposure to K +?red cell resull the prod of anti K ab
A
K ag
9
Q
k aag has frquency of 99.9% thats why hat is rarely encountered
A
anti k
10
Q
Precursor substance of the Kell Ag
A
Kx
11
Q
Present on wbc and rbc most individual
A
Kx
12
Q
If Kx is lacking from red cell the cells have an abnormal shape which is
A
Acanthocytes
13
Q
Acanthocytes in shape and reduced in vibo survival what ohenotype
A
Mcleod
14
Q
The absence of Kx from leukocytes has been described with dse
A
CGD
15
Q
Most common gene complex
A
Kell blood group
16
Q
Reduced expression of kell ag
A
Mcleod syndrome
17
Q
Mcleod syndrome ass with
A
HA and CGD
18
Q
This is usually igg and require AHG
A
Kell ab
19
Q
Rare reaction in saline
A
Kell ab
20
Q
Implicated in Htr and Hdn
A
Kell ab
21
Q
Is a very common ab
A
Anti K
22
Q
Many ag in this system and some are alleles
A
MNSs
23
Q
MNSs ass with
A
Gpa and Gpb
24
Q
Four gene complexes
A
MS Ms NS Ns
25
Other alleles of MNSs
Mg, Mc, Mk, Mr, Mz, Mv, Na, T1m, Sj, S2
26
M and N ag amino acid composition
Glycophorin A
27
M ag amino acid
Serotonin
Sertonin
theronin
theronin + glycine
28
N ag amino acid
Leucine
Serotonin
threonine
Threonine + glycose
29
S, s ag amino acid
Glycophorin B
30
S contains what AA
Methionine
31
s contain what AA
Threonine
32
Acts as anti zN
Vicea gaminea
33
Ab of MNS are
Polar opposites
34
MNSs demonstrate
Dosage effect
35
Codominant allele in paternity
M and N
36
MNSs are discovered by
Levine and Lansteiner
37
MNSs differe from ABO ag in 3 ways
Ag found in red cells and tissue and not in secretion
Anti M and N resukt of transfusion and pregnancy
Anti M and N rarely occur naturally
38
Anti M and anti N ab are
Natural and Igm
39
Anti S, s, and U
Exposure igg
40
Transfusion reaction due to
anti S and anti s
41
Hdn due to
Anti s and anti U
42
Medico legal cases
Paternity
43
Paternity testing in Father NN ANTI M AND ANTI N
Negative and 3+
44
Paternity testing in Father MM ANTI M AND ANTI N
4+ and negative
45
Paternity testing in baby MN ANTI M AND ANTI N
3+ 3+
46
Usually Igm and room temp and some at AHG
Anti S ab
47
Destroyed by enzyme
Anti S ab
48
Rare Htr and Hdn
Anti S ab
49
Usually Igg and Ahg in MNSs
Anti s and anti U
50
Not detroyed by enzyme
Anti s and anti U
51
Htr and Hdn
Anti s and Anti U
52
Found as aarm autoab and dies not react well with rh null cells
Anti U
53
Common Ag that detected in MNSs
Anti Mg
54
This is more commonly found in oriental particularly filipino
JK (a-b)
55
Variable expression with time
Kidd
56
Exposure requiring warm igg
Kidd
57
Usually require iGg and Ahg
Angi Jka and Jkb ab
58
Bind complement
Anti jka and jkb
59
Enhanced by enzymes
Anti jka and angi jkb
60
Seldom potent and deteriorate rapidly
Anti jka and anti jkb
61
Classic delayed htr
Anti jka and anti jkb
62
Found in some Jka-b- individual
Anti Jk3
63
Reacts with Jka and Jkb
Anti Jk3
64
Importance blood group that demostrate kultiple method for inheritance of null cell type
Lutheran
65
Lub how many percent
99
66
Lua how many percent
8
67
Lutheran dominate inhibitor gene
InLu
68
Recessive lack of Lu gene
Lulu
69
Sex inhibitor gene
Lu a-b- inheritance
70
Not common,reacts in saline but can be igg and require Ahg give agglutination, unclear about htr and hdn
Anti Lua
71
Reacts with all but lua-b- of the recessive type
Anti Luab or anti Lu3
72
Rare most igg and require ahg probably htr and hdn
Anti Lub
73
Other ab reacts with rare lulu phenotypes found in
Lua-b-
74
Found in chipoawah native americans and japanese and chknese
Dia
75
Uncommon ab ahg reaction and important in htr and hdn
Diego Dia
76
Marker in mongolian ancestry
Diego Dia
77
Common autoab very high frequency ab
Anti Wrb
78
Nine ag all normal individuals are either Rg + ir Ch+
Chido rogers
79
Use plasma inhibition
Htla
80
Deterrminants on c4 molecules and linked to HLA
Chido rodgers
81
Sex linked inheritance
Xg
82
Located in short arm of x chromosome
Xg
83
Destroyed by enzyme treatment
Xg
84
Found in glycophorin c and d which ass witg rbc membrane band 4.1
Gerbich
85
Ab usually igg which require ahg and clinically significant
Gerbich
86
Ab are rare
Schianna
87
Schianna under 0.3 percent
Schianna 2
88
Sch under 100%
Schianna 1 and 3
89
Found in aquaporin -1
Colton
90
Null phenotype has been found and ass with gen abnormality and anemia
Colton
91
Coa -99.7
Colton1
92
Coa 100
Coa3
93
Coa 10.7
Coa 2
94
Found in decay acceperating factor daf or cd55
Cromer
95
Total absence of cromer ag is observed in
Pnh 3 rbc
96
For,erly cartwright
Yt
97
Yt 0.2%
Ytb
98
Yt 99.8
Yta
99
Add ag added holly gregory and joseph
Dombrock
100
Uncommon ab htr and hdn
Dombrock
101
Found in complement receptor 1 cr1 or cd35
Knops
102
Decreased expression in cases of sle and cold agglutinin dse
Knops
103
Found on semaphorin cdw108
John milton hagen blood group system
104
Ansene of JMH found in
Pnh 3
105
Important in HLa typing
Bennett goodspeed ag
106
Bga
Hla b7
107
Bgb
Hla b17
108
Bgc
Hla 28
109
Destroyed by treating rbc ag with chloroquine or edta glycine hcl
Bg ab
110
Unaffected ezyme class
Colton
Diego
Kell
111
Decreased enzyme class
MNS system
Duffy
Lutheran
112
Enhanced
```
Abo h system
Lewis
I system
P
Rh
Kidd
```
113
Naturally occuring
Abo, lewis, P1, Mn, Lua
114
Clin significant
Abo rh kell duffy kidd
115
Warm ab
Rh kell duffy, kidd
116
Cold ab
M, N, P1
117
Usually react in AHg
Kell duffy kidd
118
Can react in any ohase of testing
Lewis
119
Detection enhanced by enzyme treatment
Rh lewis kidd p1
120
Nkt detected with enzyme treatment of test cell
M, N, Duffy
121
Enhanced by acidification
M
122
Show dosage
Rh, MNS, Duddy, Kidd
123
Bind complement
I, kidd, lewis,
124
Cause in vitro hemolysis
Abo, lewis, kidd some P1
125
Labile in vivo and invitro
Kidd
126
Common cause of anamenstic response
Kidd
127
Produced from the precursor substance Kx that is coded by gene XK xon the X chromosome
Kell blood grouo
