Autoab Flashcards

1
Q

A positive autocontrol or dat may indicate

A

Autoab

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2
Q

If the pt has not been transfused the pt may have an

A

Autoab coating in their own cells

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3
Q

If pt has been transfused the pt may have an

A

Alloab coating transfused cells

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4
Q

Mini cold panels can be used to help identify

A

Cold autoab

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5
Q

Anti I is an autoab what are usually included

A

Cord cells

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6
Q

How to get a positive DAT

A

Test for invivo coating rbc with ab

Ahg is added to washed pt red cell ti detemine

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7
Q

This react at rt with not all panels cells and give a posituve autocontrol

A

Cold autoab

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8
Q

The dat usually pos with

A

Ati c3 AHG

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9
Q

Cold autoab due to

A

Mycoplasma pneumoniae, im, or cold agglutinin

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10
Q

If the ab remain, what can be performed

A

Peewarmed technique

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11
Q

Is another technique in whc the autoab is removed from the patient serum usung their own red cell

A

Autoadsorption

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12
Q

Red cells, serum, saline are incubated at 37 re combines

A

Prewarmed technique

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13
Q

More common that cold ab

A

Warm ab

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14
Q

Positive dat due to igg ab coating the red cell

A

Warm autoab

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15
Q

Majority of the oanel or screening cells will be positive

A

Warm autoab

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16
Q

The rh system seem to be main target altho other occur

A

Warm autoab

17
Q

Used to remove ab

A

Eluate

18
Q

Testing eluate is useful in investigation of

A

Hdn
Transfusion rxns
Autoimmune dse

19
Q

How do u get a warm autoab

A

Idiopathic
Known disorder leukemia, preg, ID
Medication

20
Q

Most common elution

A

Acid elution

21
Q

It lowers ph, causing ab to dissociate

A

Acid elution

22
Q

Dissolve bilipid layer of rbc

A

Organic solvents ether chloroform

23
Q

Elution methods

A

Acid ekution
Organic solvents
Freeze thaw
Heat

24
Q

Free ab from sensitized eed cell so that ab can be identified

A

Elution, dat is pos

25
Q

Used ti investigate underlying alloab

A

Adsorption

26
Q

Used to dissociate igg ab from the rbc

A

Zzap or chloroquine diphosohate

27
Q

What are rgts to dissociate igg from rbc without damaging the ag

A

Chloroquine diphosphate
Glycine
Edta

28
Q

Derivative used as antimalarial

A

Quinolone

29
Q

Partial removal may be enough to ag type the cell or to used for autoadsorption of warm autoab

A

Chloroquine diphosphate

30
Q

May not remove autoab completely fom dat positive cells

A

Chloroquine diphosohate

31
Q

Auto ab can be

A

Warm or cold ab