Abo Blood Group Flashcards

1
Q

Majority pf blood group ag are what

A

Immunogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Immunogen are able to

A

Elicit antibody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Mediated immune response introduced as a foreign subs into a responsive host

A

Immunogenicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

It appears to be weak at birth but at the age of what year, this reach final strength

A

Antigen A. After one year, agglutinogens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Abnormal ag maybe found as

A

Acquired leukemia (weak A ag) and cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Certainly tge most immunogenic and thus all blood transfused must be matched for these ag betweem tye blood donor and the recepients

A

A, B, D ag

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

AfteD ag, yhis is the most immunogenic

A

K

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Most important usef for blood transfusion

A

Abo and rhesus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The presence or absence of A, B , H Ag are controlled by

A

H Ag and ABO genes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The presence or absence of ABH Ag are controlled by

A

H gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The presence and absence of the ABH Ag in secretion is indirectly controlled by

A

Se gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Site of attachment of the immunodominat sugar

A

Paragloboside

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Codes for an enzyme that adds n acetylgalactosamine to the terminal sufar of the H ag

A

A gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Codes for an enzyme that adds D galactosyltransferase to the terminal sugar of the H Ag

A

B gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

It detected by using anti H antiserum derived from what

A

H Ag, ulex europeus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

It is the foundation upon which A and B ag are built

A

H ag

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Codes for enzyme that add a sugar to the H Ag

A

A and B genes

18
Q

These are present at the terminal ends of the chair and confe the ABO Ag specificity

A

Immunodominant sugar

19
Q

Secretors are controlled by

A

H and Se gene

20
Q

The secretor gene consist of 2 alleles

A

Se and se gene

21
Q

It is responsible for the expression of the H ag on glycoprotein structure kocated in the body secretion

A

Se gene

22
Q

If the Se allele is inherited as SeSe or Sese the person is called

A

Secretor

23
Q

This express soluble forms of the H ag in secretion that can then be converted to A or B Ag

A

Secretors

24
Q

Individual who inherit the sese gene are called

A

Non secretors

25
Q

The se allele is what

A

An amorph

26
Q

Aka direct typing

A

Forward typing

27
Q

Other name of forward typing

A

Routine typing or cell typing

28
Q

Involves the determination pf unknown rbc agglutinogens by testing 2% Rbc saline suspension with known anti sera

A

Forward typing

29
Q

Indirect typing

A

Backward tyoing

30
Q

Other word for backward typing

A

Back uo typing

31
Q

Determination of unknown Ab in the serum using rbc suspension of known types.
Employed as confirmatory test

A

Backward typing

32
Q

There are two potentional precursor subs fpr ABH Ag

A

Type 1 and Type 2

33
Q

precursor has a terminal galactose linkage to a subterminal N acetylglucosamine in a 1-3 linkage

A

Type 1

34
Q

The sake combine in 1-4 linkage in

A

Type 2

35
Q

ABH Ag on red cell are derived form

A

Type 2 chains

36
Q

ABH Ag in plasma are made from both from

A

Type 1 and. Type 2 precursor

37
Q

After the fucose is added to the type 2 chain the structure is termed

A

Type II H

38
Q

H1 and H2 are what

A

Simple straight chain glycolipids

39
Q

H3 and H4 are

A

Branched chain

40
Q

Refer to genetically encoded antigen system on erythrocyte, leukocyte, pla,a and platelets

A

Blood group antigen