Abo Blood Group Flashcards

1
Q

Majority pf blood group ag are what

A

Immunogen

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2
Q

Immunogen are able to

A

Elicit antibody

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3
Q

Mediated immune response introduced as a foreign subs into a responsive host

A

Immunogenicity

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4
Q

It appears to be weak at birth but at the age of what year, this reach final strength

A

Antigen A. After one year, agglutinogens

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5
Q

Abnormal ag maybe found as

A

Acquired leukemia (weak A ag) and cancer

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6
Q

Certainly tge most immunogenic and thus all blood transfused must be matched for these ag betweem tye blood donor and the recepients

A

A, B, D ag

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7
Q

AfteD ag, yhis is the most immunogenic

A

K

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8
Q

Most important usef for blood transfusion

A

Abo and rhesus

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9
Q

The presence or absence of A, B , H Ag are controlled by

A

H Ag and ABO genes

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10
Q

The presence or absence of ABH Ag are controlled by

A

H gene

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11
Q

The presence and absence of the ABH Ag in secretion is indirectly controlled by

A

Se gene

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12
Q

Site of attachment of the immunodominat sugar

A

Paragloboside

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13
Q

Codes for an enzyme that adds n acetylgalactosamine to the terminal sufar of the H ag

A

A gene

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14
Q

Codes for an enzyme that adds D galactosyltransferase to the terminal sugar of the H Ag

A

B gene

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15
Q

It detected by using anti H antiserum derived from what

A

H Ag, ulex europeus

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16
Q

It is the foundation upon which A and B ag are built

A

H ag

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17
Q

Codes for enzyme that add a sugar to the H Ag

A

A and B genes

18
Q

These are present at the terminal ends of the chair and confe the ABO Ag specificity

A

Immunodominant sugar

19
Q

Secretors are controlled by

A

H and Se gene

20
Q

The secretor gene consist of 2 alleles

A

Se and se gene

21
Q

It is responsible for the expression of the H ag on glycoprotein structure kocated in the body secretion

22
Q

If the Se allele is inherited as SeSe or Sese the person is called

23
Q

This express soluble forms of the H ag in secretion that can then be converted to A or B Ag

24
Q

Individual who inherit the sese gene are called

A

Non secretors

25
The se allele is what
An amorph
26
Aka direct typing
Forward typing
27
Other name of forward typing
Routine typing or cell typing
28
Involves the determination pf unknown rbc agglutinogens by testing 2% Rbc saline suspension with known anti sera
Forward typing
29
Indirect typing
Backward tyoing
30
Other word for backward typing
Back uo typing
31
Determination of unknown Ab in the serum using rbc suspension of known types. Employed as confirmatory test
Backward typing
32
There are two potentional precursor subs fpr ABH Ag
Type 1 and Type 2
33
precursor has a terminal galactose linkage to a subterminal N acetylglucosamine in a 1-3 linkage
Type 1
34
The sake combine in 1-4 linkage in
Type 2
35
ABH Ag on red cell are derived form
Type 2 chains
36
ABH Ag in plasma are made from both from
Type 1 and. Type 2 precursor
37
After the fucose is added to the type 2 chain the structure is termed
Type II H
38
H1 and H2 are what
Simple straight chain glycolipids
39
H3 and H4 are
Branched chain
40
Refer to genetically encoded antigen system on erythrocyte, leukocyte, pla,a and platelets
Blood group antigen