Abo Blood Group Flashcards
Majority pf blood group ag are what
Immunogen
Immunogen are able to
Elicit antibody
Mediated immune response introduced as a foreign subs into a responsive host
Immunogenicity
It appears to be weak at birth but at the age of what year, this reach final strength
Antigen A. After one year, agglutinogens
Abnormal ag maybe found as
Acquired leukemia (weak A ag) and cancer
Certainly tge most immunogenic and thus all blood transfused must be matched for these ag betweem tye blood donor and the recepients
A, B, D ag
AfteD ag, yhis is the most immunogenic
K
Most important usef for blood transfusion
Abo and rhesus
The presence or absence of A, B , H Ag are controlled by
H Ag and ABO genes
The presence or absence of ABH Ag are controlled by
H gene
The presence and absence of the ABH Ag in secretion is indirectly controlled by
Se gene
Site of attachment of the immunodominat sugar
Paragloboside
Codes for an enzyme that adds n acetylgalactosamine to the terminal sufar of the H ag
A gene
Codes for an enzyme that adds D galactosyltransferase to the terminal sugar of the H Ag
B gene
It detected by using anti H antiserum derived from what
H Ag, ulex europeus
It is the foundation upon which A and B ag are built
H ag