Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Blood Banking > Blood Therapy 2 > Flashcards

Blood Therapy 2 Flashcards

1
Q

A single unit can be isolated from every units of donated blood by centrifuging the blood within the closed collection ystem to separate plts from rbc

A

Platelet concentrates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

As the plt number is inadequate Four to six units are pooled together called

A

Whole blood derived or random donor pooled plts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Advantage of plts conc

A

Lower cost
Ease of collection
Processing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Disadvantage of plt concentrate

A

Recipients exposure to multiple donor in a single transfusion and logistic issues related to bacterial testing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Plts are collected in how many hours in apheresis procedure

A

2-3hrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

In apheresis what are removed and what returned to donor

A

Plts and wbc removed, rbc and plasma returned

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

A typical apheresis platelet unit

A

3 - 6 x10^11

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Advantage if single donor apheresis plts

A

Exposure of the recipient to a single donor rather than multiple donor

Ability to match donor and recipients characteristics such as HLA, Cmv, and blood type certain recipients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which contain less than 5x10^6 leukocytes

A

Plts, pooled, buffy coat deried, leucocyte depleted pool pf plts, derived from buffy coat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

A single donor plt component containing less than 5x10^6 leucocytes

A

Plts, apheresis, leucocyte depleted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

This component indicated for pt with reaction to plasma containing components

A

Pksts, suspended in additive, keukocyes depleted, plts concentrate,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Volume of pc

A

150-450ml

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Ph of pc

A

Bet 6.4-7.4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Leuko ct in pc

A

Less than 5x10^6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Shelf life of pc

A

5 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Practical shelf life of pc

A

2.3-3days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Pkts ar stored in

A

Room temp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Cold induces

A

Clustering of vwf receptor kn tge plt surface and morphological changes of plts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Leading to enhanced

A

By hepatic macrophages and reduced plts survival in the recipients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Plts are stored at a core temp of

A

22deg +/- 2 deg with agitation for 5 days in closed system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Plts are stored in room temp to engabce

A

Bacterial growth and third leading cause of HTR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

For any pt who develop a fever within 6 hrs after receiving plts

A

Sepsis from plts considered

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

One plt concentrate is usually given to most

A

Adukt pt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

In small childern dec 20kgs and 10-15ml

A

One plt conc used

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

In older children

A

An adukt dose of plts should be used

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

One plt comc ususlly produces and increase of approx how many plts and how many kg in pt

A

7000-10000mm3 at 1 hr to 70kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Ten units f plt concentrate are required to inc plt ct by

A

100000 cells/mm3

28
Q

Dose computation

A

PI X BV X F-1

29
Q

Prepared from whole blood by separating snd freezing plasma 200-250’l within 6hr donation

A

Fresh frozen plasma

30
Q

Ffp may be stored up to and how many deg

A

1yr -18 deg

31
Q

It contains aol coagulation factors and othe protein

A

Ffp

32
Q

Order the ffp should be what

A

30-37 deg with constant agitation

33
Q

After thawing of ffp can be stored at what temp and what if room temp

A

4deg for 24hrs but if room temp 4hrs

34
Q

Diff types of ffp

A 
Fresh frozen plasma
F24plasma
Cryosupernatant
Liquid plasma
Solvent detergent treated plasma
35
Q

Plasma frozen at 18 deg within 6hrs of donation

A

Ffp

36
Q

Plasma frozen at 18det within 24 hrs cryosuoernatant and solvent detergent treated plasma liquid

A

F24 plasma

37
Q

Teh plasma remaining after removing cryoprecipitate

A

Cryosupernatant

38
Q

Cryosupernatant also referrref as

A

Cryo poor plasma

39
Q

Spused as plama replacement in pt with thrombicytopenic purpura

A

Cryosupernatant

40
Q

Vitamin def correction of major bleeding in the setting of

A

Warfarin coagulation

41
Q

Remival of cryoprecipitate from plasma does nit deplete

A

Vut k dependent clotting factors

42
Q

Plasma nit immmediately frozen as ffp or f24 and stored at 1-6deg

A

Liquid plasma

43
Q

Used preparation of plasma derivative slike albumin, factor conc, abd immuniglobulins

A

Liquid plasma

44
Q

Treatment of pooled plasma prior o freezing with a solvent and non ionic detergent inactivates a number of lipid envelope virus, hiv, hep b and c

A

Somvent detergent palsma

45
Q

Non enveloped viruses like parvob19 and hep a arenot inactivated by this process and prions

A

S/d plasma

46
Q

This method used ti inactivate viruses in ig and coagulation factors

A

S/d plasma method

47
Q

Has similar levels of most clotting factors and similar hemostatic properties as standard ffp

A

S/d plasma

48
Q

Twi emthod to collect this component

A

Random donor pooled pt

Single donor apheresis platelets

49
Q

The inuitial therapeutic dose of ffp average

A

10-15ml/kg to obtain 30% factor

50
Q

Repeating dosing should follow the resukt pf serial diagnostic coagulation test such as

A

Pt and aptt

51
Q

Ffp in trauma

A

Tarditional method fluids, ffp, rbc only abnormal coagulation result problem dikutional coagulopathy resulting in prolonged microvascular bleeding
Recent studies show improved outcomes with higher ration of cell unit to ffp 3:2

52
Q

Cryoprecipitate Originally it was a developed as a therapy for

A

Hemophilia A

53
Q

Cryoprecipitate enrinched with

A

Fibrinogen, fac 8, vwf, factor 13

54
Q

When ffp is thawed at 4 deg

A

Prrcipitate formed, resuspend snall volume of plasma and refrozen 18deg for 1 year

55
Q

1 unit of whole blood contains

A

250 ml plasma

56
Q

One unit of cryoprecipitate volume cobtains 10-20ml in to

A

150-250 mg

57
Q

80-100 units of

A

Factor 8

58
Q

50-100 units of factor

A

13

59
Q

50-60mg of

A

Fibronectin

60
Q

40-70% of

A

Vwf conc

61
Q

Essential for the fromation promary hemostatic plus maintanance of normal hemostasis

A

Plts

62
Q

Thrombocytopenia may csused

A

Dec plt production
Increase destruction
Massive transfuison

63
Q

Dic

A

Increase destruction

64
Q

Because of rapid use of olt for hemostasis and dilution plt by resuscitation fouids

A

Massive transfuison

65
Q

After chemotherapy or malignancy

A

Dec plt prodyction

66
Q

Indicated for patients

A

Who are bleeding due to thrombipocytopenua
Who have abnormal fuctioning
Who have plt ct under 20000 ul
Who have undergone chemotherapy, dic, massive transfusion

Blood Banking (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions