osteoporosis Flashcards
osteoclasts
break down bone
osteoblasts
help form bone
age of peak bone mass
30s, with decline after mid 30s
____ million people in the world have OP, ___ million in canada
200, 2
%% of fractures over 50 are caused by OP
80%
Do men or women get OP more? Why?
women, menopause causes greater bone loss
T/F OP fractures are more common than heart attacks, strokes or breast cancer combined
- asian and hispanic are at higher risk
T, F - caucasian and asian
why is OP called the silent theif
bone loss occurs without symptoms
what is the gold standard of OP diagnosis
Dexa
Which of the following is a correct T- score
- Osteopenia = T score between + 2.5 and - 2.5
- Osteoporosis = T score below - 2.5
- Osteoporosis = T score below - 1
- Severe osteoporosis = T score below - 2 + fragility fracture
- T score below -2.5
Penia = +2.5 and -1
Severe = below -2.5 + fracture
Which of the following is not a risk factor for OP
- Age
- Low protein, calcium or vitamin D
- excessive alcohol, caffeine, sodium or smoking
- high BMI or physical inactivity
- Low BMI not high
Primary OP
no underlying systemic cause, more common
primary OP types
type I: post-menopausal (estrogen)
type II: senile (aging skeleton and calcium deficiency)
secondary OP
cause by secondary conditions (inflammation, steroids, smoking, alcoholism)
T/F Bisphosphonates and selective estrogen receptor modulators are antiresorptive meds that affect exercise response
- Standardized testing is ok to use with precautions for falling
- People with kyphotic spine cannot use cycle ergometer for testing
F - they do not affect the exercise response, they reduce osteoclast activity to increase BMD. T, F - should use cycle, not treadmill
