Epigenetics Flashcards

1
Q

epigenetics

A

way of modifying DNA without changing sequencing (how much or what is expressed)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

which is not a type of DNA mod
- DNA myelination
- histone modification
- base pair rebinding
- chromatin remodeling

A
  • no base pair change
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are the effects of DNA mods on chromatin and DNA

A

affects chromatin structure, therefor DNA accessibility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how does methyl effect chromatin

A

inactivates chromatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What happens to global DNAm with age

A

decreases, but specific regions of DNA increase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

epigenetic drift

A

decrease in DNAm in regions that had high DNAm (and vice versa)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

how does HIIT affect DNAm

A

immediately decreases DNAm but increase in fat cells after 6 months of training

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which environmental factor does not affect epigenetics
- diet
- nutrition
- weight
- actvity

A

weight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

epigenetic clock

A

amount of modification to DNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Is DNAm tissue independent or tissue specific?

A

both

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What predicts chronological age within 2 years?

A

DNAm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

epigenetic age acceleration

A

when DNA appears older than you

How well did you know this?
1
Not at all
2
3
4
5
Perfectly