MSK system Flashcards
Which of the following is not a muscle morphology change with age
- muscle atrophies and changes body composition
- fiber size and number decreases
- capillary to fiber ratio increases
- loss of type II fibers from alpha MU loss
capillary to fiber ration DECREASES
T/F Loss of type II fibers results in reduced power movements
- Greater number of type I fibers with age leads to greater fatigue resistance
T, F - does not translate to fatigue resistance due to other changes with age
Which of the following biomarkers of energy production does not decrease with age
- PFK
- HK
- COX
- CS
PFK
which of the following are rate limiting glycolytic biomarkers
- PFK
- HK
- COX
- CS
PFK and HK
which of the following are related to mito respiration
- PFK
- HK
- COX
- CS
COX and CS
Which of the following is false
- loss of fibers can be reversed with PA
- muscle can still hypertrophy when older
- staying active will result in higher FFM
- staying active helps maintain MUs with age
- loss of fiber CANNOT be reversed, but rate can be slowed with PA
Atrophy
decreased CSA due to fiber number and area loss
Which of the following does not affect hypertrophy
- frequency
- type
- intensity
- duration
frequency
anabolic resistance
aging is associated with reduced protein synthesis from protein resistance
T/F protein dose required to stimulate synthesis is 40% lower in older adults
F - 40% lower in younger people, meaning younger need less protein
which of the following is false of myogenic factors in sarcopenia
- there is a loss of both MHC type I and type II due to reduced activity in age
- loss of MHC results in slower contractile shortening
- there is a decrease in anabolic hormones with age
- there is a decrease in ca++ release and uptake from the SR with age
- changes in E-C coupling reduce contractile shortening speed
- changes in E-C coupling reduce FORCE
Which of the following people does not have sarcopenia
- a woman with a muscle mass (LMM) of 4.0 kg
- a man with a muscle mass (LMM) of 5.0 kg
- a woman with grip strength of 25 kg
- a man with grip strength of 25 kg
- woman with grip
which is false of frailty
- young people can be diagnosed with frailty
- frailty is the reduced ability to respond to stressors
- appearance can always determine frailty
- status of frailty is not permanent
- appearance can be deceiving
what is the frailty continuum
- robust: no symptoms
- pre-frail: 1-2 symptoms
- frail 3+ symptoms
which of the following is not a possible symptom of frailty
- low strength
- fatigue and exhaustion
- decreased flexibility
- involuntary weight loss
- decreased flexibility. others may include slowness, decreased balance and mobility, and low PA
