Opiods

Question 1

Prototype opiod (full agonist)

SE: miosis, respiratory depression, constipation

Answer 1

Morphine

Question 2

OPIOD:

For Severe pain, breakthrough cancer pain
available in lollipop from or transdermal patch

Answer 2

Fentanyl

100x potent

Question 3

Opiod of choice for acute pancreatitis, does not cause miosis

SE: seizures

Answer 3

Meperidine

Question 4

OPIOD:

Replacement therapy for opiod dependence

Answer 4

Methadone

Question 5

OPIOD:

Cough suppression

Answer 5

Dextromethorpan

Codeine

Question 6

OPIOD:

Balanced anesthesia
frequently abused by healthcare professionals

Answer 6

Nalbuphine

Question 7

Antidote to opiod overdose

Answer 7

Naloxone

Question 8

Treatment of opiod dependence

Answer 8

Naltrexone

Question 9

Which opiods have the shortest and longest half-lives?

Answer 9

Ramifentanil: Shortest half-life (3-4 minutes)

Buprenorphine: longest half life (4-8 hours)

Question 10

What is the triad of OPIOID overdose?

Answer 10

PCR

Pupillary constriction
Comatose state
Respiratory depression