Anti-Cholesterol Agents Flashcards
HMG-CoA reductase inhibitor, lowers LDL
SE: hepatotoxicity, rhabdomyolysis, and myopathy
Statins
Anti-cholesterol agents
Bile acid binding resin, Lowers LDL
SE: constipation, steatorrhea
Cholestyramine
Anti-cholesterol agents
Cholesterol absorption blocker, lowers LDL
SE: Hepatotoxicity especially with statin use
Ezetamide
Anti-cholesterol agents
Reduces all building blocks for hyperlipidemia, increase HDL, and lowers LDL & TG
Niacin
Anti-cholesterol agents
PPAR-a activator, upregulates lipoprotein lipase; lowers TG
SE: gallstones, additive myopathy
Fibrates
Anti-cholesterol agents
Why are statins used in the management of coronary artery disease.
For stabilization of atherosclerotic plaques.
What are the drugs that cause FLUSHING?
CAraVAN
Calcium channel blockers
Vancomycin
Adenosine
Niacin
Drug of choice for Hypercholesterolemia
Statins
Drug of choice for Hypertryglyceridemia
Fibrates
Drug of choice for low HDL
Niacin
Lowers TG
FIBRATES
NIACIN
Increase risk of cholelithiasis?
Combination of
Resin + Fibrates
Contraindicated in Gout and DM patients
NIACIN
SE: hyperuric and hyperglycemia
Increase risk of hepatotoxicity in combination of statin and ______
EZETIMIBE
