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Things to know > Oncology part 2 > Flashcards

Oncology part 2 Flashcards

1
Q

Which of the following are Alkylating Agents

A. Cisplatin 
B. Cyclophosphamide
C. Doxorubicin
D. Daunorubicin
E. Carmustine
F. Carboplatin 
G. Ifosfamide
H. Bendamustine
I. Mitoxantrone 
J. Busulfan
K. Melphalan 
L. Lomustine
A

B. Cyclophosphamide

E. Carmustine

G. Ifosfamide
H. Bendamustine

J. Busulfan
K. Melphalan
L. Lomustine

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2
Q

Which of the following are Know to cause Hemorrhagic Cystitis?

A. Cisplatin 
B. Cyclophosphamide
C. Doxorubicin
D. Daunorubicin
E. Carmustine
F. Carboplatin 
G. Ifosfamide
H. Bendamustine
I. Mitoxantrone 
J. Busulfan
K. Melphalan 
L. Lomustine
A

B. Cyclophosphamide

G. Ifosfamide

Prevent with Mesna (Mesnex)

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3
Q

Which of the following are know to cause pulmonary Fibrosis?

A. Cisplatin 
B. Cyclophosphamide
C. Doxorubicin
D. Daunorubicin
E. Carmustine
F. Carboplatin 
G. Ifosfamide
H. Bendamustine
I. Mitoxantrone 
J. Busulfan
K. Melphalan 
L. Lomustine
A

E. Carmustine

J. Busulfan

L. Lomustine

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4
Q

Which of the following are Platinum Based Compounds?

A. Cisplatin 
B. Cyclophosphamide
C. Doxorubicin
D. Daunorubicin
E. Carmustine
F. Carboplatin 
G. Ifosfamide
H. Bendamustine
I. Mitoxantrone 
J. Busulfan
K. Melphalan 
L. Lomustine
A

A. Cisplatin –> Remember Nephrotoxicity, and Ototoxicity

F. Carboplatin

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5
Q

Which of the Following are Anthracyclines

A. Cisplatin 
B. Cyclophosphamide
C. Doxorubicin
D. Daunorubicin
E. Carmustine
F. Carboplatin 
G. Ifosfamide
H. Bendamustine
I. Mitoxantrone 
J. Busulfan
K. Melphalan 
L. Lomustine
A

C. Doxorubicin –> Hand foot syndrome
D. Daunorubicin –> Both cause RED urine discolor

I. Mitoxantrone –> Causes BLUE urine discolor

–> All Cardiomyopathy

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6
Q

Which of the Following are Vinca Alkaloids?

A. Paclitaxel 
B. Irinotecan
C. Vincristine 
D. Docetaxel
E. Topotecan
F.  Vinblastine 
G. Etoposide 
H. Paclitaxel albumin bound (Abraxane)
A

C. Vincristine

F. Vinblastine

–> For BOTH REMEMBER IV ONLY, IM is fatal

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7
Q

Which of the Following are Taxanes?

A. Paclitaxel 
B. Irinotecan
C. Vincristine 
D. Docetaxel
E. Topotecan
F.  Vinblastine 
G. Etoposide 
H. Paclitaxel albumin bound (Abraxane)
A

A. Paclitaxel
–> Both Severe hypersensitivity reactions, use NON PVC bag and tubing
D. Docetaxel –> Cuases SEVERE fluid retention

H. Paclitaxel albumin bound (Abraxane)

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8
Q

Which of the following are Topoisomerase I inhibitors

A. Paclitaxel 
B. Irinotecan
C. Vincristine 
D. Docetaxel
E. Topotecan
F.  Vinblastine 
G. Etoposide 
H. Paclitaxel albumin bound (Abraxane)
A

B. Irinotecan –> Delayed Diarrhea, Treat with loperamide

E. Topotecan

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9
Q

Which of the following are Topoisomerase II inhibitors

A. Paclitaxel 
B. Irinotecan
C. Vincristine 
D. Docetaxel
E. Topotecan
F.  Vinblastine 
G. Etoposide 
H. Paclitaxel albumin bound (Abraxane)
A

G. Etoposide

–> For the IV version use Non PVC IV bag

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10
Q

Which the following are Pyrimidine analog Antimetabolites?

A. Methotrexate
B. Pemetrexed
C. Capecitabine 
D. Xeloda 
E. Trexall 
F. Fluorouracil
A

C. Capecitabine = Xeloda
D. Xeloda

F. Fluorouracil

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11
Q

Which the following are Folate Antimetabolites?

A. Methotrexate
B. Pemetrexed
C. Capecitabine 
D. Xeloda 
E. Trexall 
F. Fluorouracil
A

A. Methotrexate = Trexall, Rasuvo, Otrexup, Xatmep
B. Pemetrexed

E. Trexall

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12
Q

Which of the following are Proteasome inhibitors?

A. Bortezomib
B. Lenalidomide
C. Carfilzomib
D. Pomalidomide
E. Everolimus
F. Thalidomide
G. Temsirolimus
H. Kyprolis 
I. Zortress
A

A. Bortezomib

C. Carfilzomib = Kyprolis

H. Kyprolis

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13
Q

Which of the following are Mammalian target of rapamycin (mTOR) inhibitors?

A. Bortezomib
B. Lenalidomide
C. Carfilzomib
D. Pomalidomide
E. Everolimus
F. Thalidomide
G. Temsirolimus
H. Kyprolis 
I. Zortress
A

E. Everolimus

G. Temsirolimus

I. Zortress

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14
Q

Which of the following are Immunomodulators?

A. Bortezomib
B. Lenalidomide
C. Carfilzomib
D. Pomalidomide
E. Everolimus
F. Thalidomide
G. Temsirolimus
H. Kyprolis 
I. Zortress
A

B. Lenalidomide

D. Pomalidomide

F. Thalidomide

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15
Q

Match the Following brands and generics

Vepesid 
Xeloda 
Revlimid
Thalomid
Velcade
Kyprolis
--------------------------------------
Bortezomib
Capecitabine
Carflizomib 
Etoposide capsules 
Lenalidomide
Thalidomide
A 
Vepesid --> Etoposide capsules 
Xeloda  --> Capecitabine
Revlimid -->  Lenalidomide
Thalomid --> Thalidomide 
Velcade --> Bortezomib
Kyprolis --> Carflizomib
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Things to know (34 decks)

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