Obstruction to Circulation Flashcards
CAD
Coronary Artery disease
Arteriosclerosis is what?
calcification of the walls of the arteries. Walls become rough & vessels become narrow, decreasing blood volume, causing pain, ischemia & impaired tissue function
Medications for the treatment of CAD
Aspirin, beta blockers, Ace Inhibitors, Lipid management
What are Statins used for & their action?
Used for Lipid management to prevent 1st &2nd MI in pts with CAD, DM or hyperlipidemia. They increase HDL, decrease LDL, decrease TG, decrease total elevation in cholesterol
What are Bile Acid Sequestrants used for & their action?
Used for Lipid management. They decrease LDL Usually given when Statins are not sufficient to lower high cholesterol
What are Nicotinic acids used for & their action?
Used for Lipid management. They decrease VLDL
What are Fibrates used for & their action?
Used for Lipid management. They decrease HDL & increase TG
What are Cholesterol absorption inhibitors used for & their action?
Used for Lipid management. They decrease LDL & total
Side effects of Statins
GI, hepatotoxicity, osteoproosis, personality changes, muscle pain, increase risk of rhabdomyolysis
rhbdomyolysis
breakdown of muscles.
Bile Acid Sequesterants side effcts
GI, osteoporosis. They can actually increase Triglyceride levels
Nicotinic acid side effects
Flushing, rashes & itching which last about 30 mins. Take aspirin to take care of flushing or take at night
Fibrates side effects
GI, Hepatic, Cholelithiasis (formation of gall stones), muscle pain, rhabdomyolysis, SHORT TERM USE ONLY
Cholesterol absorption inhibitors example
Zetia
Psyllium fiber is found in what & what does it do?
Found in Metamucil, it helps reduce cholesterol
Antihypertensive medication
ACE inhibitors, Beta Blockers, Calcium Channel Blockers
Antiplatlet Medications
Aspirin, Clopidogrel (Plavix)
What kinds of things cause chest pain?
Rib & muscle inflammation, Pneumonia, Heart Attack, Angina, Galbladder inflammation, Gastroesophageal Reflux Disease
Unstable Angina, Angina + recurrent attacks at rest are both considered?
Acute Coronary Syndrome
Prodromal symptoms that appear a month before an episode of Acute Coronary Syndrome (ACS)
Fatigue, SOB, Sleep disturbances, Anxiety, Fleeting chest discomfort. Share these symptoms with people at risk for ACS
What can cause Angina?
Spasm, obstruction or both of the heart, Inflammation, infection of arteries, Injury
What is the most common cause of Angina?
Coronary Artery Disease
Progressive Angina leads to what?
heart attack because plague ruptures & clots attach which leads to hart attack.
Stable Angina is reversed by?
Diet and exercise
Why do you get pain with Angina?
because the heart is deprived of O2