nucleus Flashcards

1
Q

what are the two ways DNA is stored

A

euchromatin: lose packed DNA which is easily acessible by transcription machinary
hetrochromatin: tight packed DNA, not used
dynamic equilibrium as genes are in use and not in use

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2
Q

how is DNA packaged

A

2nm fibers bind with histone 2-4 to form nucleosomes making a 10nm fiber. then with histone 1 to form a 30nm fiber, which futher fold toa 300nm fiber.
when cell division this forms a metaphase cromosome

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3
Q

discribe the nucleopore complex

A

nucleoporins form a nucleopore complex which is a chanel which streaches the inner membrane through the perinuclear space through the outermembrane space

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4
Q

what is able to travel through the nuclear pore complex, into nucleaus and out of nucleaus

A

into: Energy, building blocks of ribosomes, signals
out of: ribosomal subunit, tRNA, mRNA

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5
Q

What is the function of the nucleolus

A

the nucleolus makes ribosomal sub units such as ribosomal protins and RNA.
ribosomes are made outside in the cytosol
they can have multiple in a cell
doesnt have any when cell is dividing

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6
Q

how is the nuclear envelope comprised

A

outer membrane-> perinuclear space -> inner membrane -> lamina (intermediate filaments which maintain shape)

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7
Q

what is the job of the nucleus

A

to store most of the cells DNA
to be the comand center to the cell
5-10um in diameter

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8
Q

what does the nucleolus make

how it it bound

A

ribosomeal RNA and ribsomal sub units

non-membrane bound regoin

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