Forms of variation of genes in a population Flashcards

1
Q

What is the hardy wineburg equ

A

Q^2 + 2pq + P^2 = 1
p+q=1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

If a proportioin of the popultion has a genetic disease (1/2500) how to work out nb of carriers

A

Q^2 = 1/2500 therefore Q = 1/50=0.02
p=1-0.02=/98
2pq=nb of carriers = 20.980.02

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

if the number of x chromosomes with a defect is 0.1 what proportion of men vs woman will exspress the disease

A

men = 0.1 *100
women = 0.1^2 *100

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe how stabilizing selection effects a population

A

Stabilising selction favors the middle allele, this type of selection disfavors either extream case

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

descibe how disruptive selection affects a population

A

disruptive selection is when the middle phnotype is not favored and being at one of the two extreams gives a better chance of survival

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe how directional selection affects a population

A

directional selection skews towards one allele or the other moving the median towards having a specific phenotype of the other making this more common

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the five types of selection

A

stabilising selection
directional selection
disruptive selection
frequency dependant selection
sexual selection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

descibe how sexual selection affects a population

A

sexual selection is when having a phenotype means you are more likely to reproduce causing more of this trait to be present in the population

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

describe how frequency dependant selection affects a population

A

Being rare is advantagous causes this rare gene to reproduce more, in the next generation this trait is now more common so the previously more common trait is rare. this flips back and fourth.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is the effect of migration on a population

A

increased genetic diversity
change in the population size
change in the % of the exsiting alleles
brings the two groups close together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is a cline

A

a cline is the effect of a change in the presense of phenotype over geographical area.
Could be due to
climate, soil type, water temprature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the exsepected recombinent frequency for unlinked vs linked genes

A

unlinked around 50%
linked, 0-50
the smaller the recombinenet frequency the closer of the chromosome the alleles are

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the founder effect

A

When some individuals from a population establish a new population elsewhere. the new population will have a much smaller pool of alleles and therefore less genetic diversity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are effects/causes of allele frequencys varry in a population

A

non random mating - inbreeding or assortive mating (breeding with simlar looking people)
Random genetic drift
bottle neck effect
the founder
effect natural selection
gene flow or migration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Why is mutation not a good way that allele frequency change

A

It is a very slow form of allele frequency change, more linked to evolution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe random genetic drift and the bottleneck affect

A

Random genetic drift is when random events cause the change in percentages of an allele across a population, impacts smaller communities more greatly

The bottlneck effect is when an external sorce causes a large reduction in the number of an allele in a population