Forms of variation of genes in a population Flashcards
What is the hardy wineburg equ
Q^2 + 2pq + P^2 = 1
p+q=1
If a proportioin of the popultion has a genetic disease (1/2500) how to work out nb of carriers
Q^2 = 1/2500 therefore Q = 1/50=0.02
p=1-0.02=/98
2pq=nb of carriers = 20.980.02
if the number of x chromosomes with a defect is 0.1 what proportion of men vs woman will exspress the disease
men = 0.1 *100
women = 0.1^2 *100
Describe how stabilizing selection effects a population
Stabilising selction favors the middle allele, this type of selection disfavors either extream case
descibe how disruptive selection affects a population
disruptive selection is when the middle phnotype is not favored and being at one of the two extreams gives a better chance of survival
Describe how directional selection affects a population
directional selection skews towards one allele or the other moving the median towards having a specific phenotype of the other making this more common
What are the five types of selection
stabilising selection
directional selection
disruptive selection
frequency dependant selection
sexual selection
descibe how sexual selection affects a population
sexual selection is when having a phenotype means you are more likely to reproduce causing more of this trait to be present in the population
describe how frequency dependant selection affects a population
Being rare is advantagous causes this rare gene to reproduce more, in the next generation this trait is now more common so the previously more common trait is rare. this flips back and fourth.
what is the effect of migration on a population
increased genetic diversity
change in the population size
change in the % of the exsiting alleles
brings the two groups close together
What is a cline
a cline is the effect of a change in the presense of phenotype over geographical area.
Could be due to
climate, soil type, water temprature
What is the exsepected recombinent frequency for unlinked vs linked genes
unlinked around 50%
linked, 0-50
the smaller the recombinenet frequency the closer of the chromosome the alleles are
What is the founder effect
When some individuals from a population establish a new population elsewhere. the new population will have a much smaller pool of alleles and therefore less genetic diversity
What are effects/causes of allele frequencys varry in a population
non random mating - inbreeding or assortive mating (breeding with simlar looking people)
Random genetic drift
bottle neck effect
the founder
effect natural selection
gene flow or migration
Why is mutation not a good way that allele frequency change
It is a very slow form of allele frequency change, more linked to evolution