Nucleic Acid Word Stimulants Flashcards

1
Q

DNA

A
Double Helix
Replicated by parent DNA
Thousands of bases
Carries genetic info from parents
Phosphodiester bond
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2
Q

DNA pairs

A

Adenine - Thymine
Guanine - Cytosine
1:1 ratio
Thousands of bases

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3
Q

Phosphodiester Bond

A

Condensation reactions

Phosphate C3 - Sugar C5 of another

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4
Q

DNA location

A

Mainly Nucleus; some Mitochondria / chloroplast

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5
Q

Nucleotide Structure

A

Pentose Sugar (deoxyribose/ribose)
Phosphate group
Nitrogen-containing organic group

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6
Q

Complementary Base Pairs

A

Adenine - Thymine/Uracil
Guanine - Cytosine
Hydrogen bonds (3 GC) (2 AT/U)

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7
Q

RNA

A
Single Sranded (phsophodiester strand)
Transcribed against DNA template
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8
Q

RNA Pairs

A

Adenine - Uracil
Guanine - Cytosine
No base ratio

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9
Q

RNA Location

A

Made in nucleus

Found in cytoplasm

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10
Q

tRNA Structure

A

Transfer RNA
70-90 bases
Clover shaped strand

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11
Q

tRNA Role

A

Binds to amino acids

Carriers to mRNA/ribose complex

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12
Q

mRNA Structure

A

Few hundred>thousands of bases

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13
Q

mRNA Role

A

Genetic material

Nucleus>Ribosome (polypeptide synthesised)

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14
Q

DNA replication location

A

Nucleus

S phase of Interphase

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15
Q

DNA Replication Steps

A

DNA double strand ‘unzips’ - h bonds break
DNA helicase
Free nucleotides in nucleus joins to complementary bases on tRNA
DNA polymerase (condensation reaction)
Two new separate strands

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16
Q

DNA Helicase

A

‘Unzips’ DNA double strand
Breaks hydrogen bonds
Hydrolysis Reactions

17
Q

DNA polymerase

A

Joins complementary nucleotides

Condensation Reaction

18
Q

Semi-Conservative Model

A
Old strand (parent - genetic continuity)
Two new strands (1 new strand, 1 old)
19
Q

Watson-Crick Model

A

Isotopes
N14 - light, top of tube
N15 - heavy, bottom of tube
Centrifuged 1st (mixed) & 2nd generation (1 light, 1 mixed)

20
Q

ATP

A

Adenosine Triophosphate

21
Q

ADP

A

Adenine Diphophate

22
Q

Inorganic Phophate

A

Pi

Phosphorylates other compounds - more reactive

23
Q

Energy

A
Some heat (ATP>ADP)
Light dependent photosynthesis, sugars oxidised by cellular respiration (ADP>ATP)
24
Q

ATP Structure

A

Adenine
Ribose
3 Phsophate groups

25
ATP properties
Soluble in H2O | Universal energy currency
26
ATP > ADP
``` ATP + H2O > ADP + Pi + Energy ADP Hydrolase (hyrdolysis) Endothermic ```
27
ADP Hydrolase
ATP to ADP | Hydrolysis reaction
28
ADP > ATP
ADP + Pi + E > ATP + H2O ATP Synthase (condensation) Phsophorylation Exothermic
29
ATP uses
``` Energy for biological processes (immediate source) Anabolic processes (Monomers>polymers) Active transport (Glucose blood>Liver) (Na+, K+ axons) Muscle contraction (fibre shortens) ```
30
Water structure
``` H2O Delta negative/positive No net charge lone pairs on O (x2) Hydrogen bond (very strong) ```
31
Water Uses
Major component of cells Solvent properties Metabolite in many metabollic reactions (condensation/hydrolysis)
32
Solubilty
In solvents - ions,polar molecules | Insoluble - non polar
33
Water properties
High surface tension Large latent heat of vaporisation High relative heat capacity
34
High surface tension
Strong cohesion (H bonds) Support columns of H2O Transport cells of plants (xylem vessels)
35
Large Latent Heat of Vaporisation
Energy to evaporate 1 g of H2O Cooling effect : Little water lost in evaporation (lots of heat energy to break h bonds) Carry away heat energy
36
High Relative Heat Capacity
Higher melting and boiling points than expected Hydrogen bonds Buffers changes in temperature