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Nuclear: High Yield Flashcards

1
Q

What is the critical organ?

A

The organ that receives the most concerning dose of radiation (this is the organ that limits the dose of the radiopharmaceutical used for that particular study)

Note: This is typically the organ that the radiotracer spends the most time in.

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2
Q

What is the target organ?

A

The organ you want a radiotracer to accumulate in

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3
Q

Critical organ for In-111 PSMA

A

Liver

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4
Q

Critical organ for I-131 MIBG

A

Liver

Note: For I-123 MIBG, its bladder.

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5
Q

Critical organ for IV Tc-99m sulfur colloid

A

Liver

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6
Q

Critical organ for Tc-99m HIDA

A

Gallbladder wall

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7
Q

Critical organ for thallium-201

A

Renal cortex

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8
Q

Critical organ for Tc-99m DMSA

A

Renal cortex

Note: Structural renal agents stay in the kidney longer than the bladder.

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9
Q

Critical organ for PO Tc-99m sulfur colloid

A

Proximal colon

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10
Q

Critical organ for Tc-99m sestamibi

A

Proximal colon

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11
Q

Critical organ for Tc-99m MAG3

A

Bladder

Note: Functional renal agents stay in the bladder longer than the kidney.

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12
Q

Critical organ for Tc-99m MDP

A

Bladder

Note: Some people think its actually bone.

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13
Q

Critical organ for I-123 MIBG

A

Bladder

Note: For I-131 MIBG, its liver.

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14
Q

Critical organ for In-111 octreotide/pentetreotide

A

Spleen

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15
Q

Critical organ for Tc-99m RBCs

A

Undamaged RBCs: Heart
Heat-damaged RBCs: Spleen

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16
Q

Critical organ for In-111 WBC

A

Spleen

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17
Q

Critical organ for Tc-99m pertechnetate

A

Stomach

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18
Q

Critical organ for gallium-67

A

Distal colon

19
Q

Critical organ for Tc-99m DTPA

A

Bladder

Note: Functional renal agents stay in the bladder longer than the kidney.

20
Q

Thallium-201 is an analog of…

A

Potassium (enters cells by Na/K ATPase)

21
Q

Gallium-67 is an analog of…

22
Q

What are the photon energies released by Tc-99m?

A

Low:

140 keV

23
Q

What are the photon energies released by I-123?

A

Low:

159 keV

24
Q

What are the photon energies released by Xenon-133

A

Low:

81 keV

25
Q

What are the photon energies released by Thallium-201?

A

Low:

  • 135 keV (2%)
  • 167 keV (8%)

Note: It is the photon energies released by thalliums daughter product (mercury-201) that are used for imaging. Mercury-201 actually gives off x-rays.

26
Q

What are the photon energies released by Indium-111?

A

Medium:

  • 173 keV (89%)
  • 247 keV (94%)
27
Q

What are the photon energies released by Gallium-67?

A

Multiple:

  • 93 keV (40%)
  • 184 keV (20%)
  • 300 keV (20%)
  • 393 keV (5%)
28
Q

What are the photon energies released by Iodine-131?

A

High:

365 keV

29
Q

What are the photon energies released by Fluorine-18?

A

High:

511 keV

Note: 2 high energy 511 keV photons are released during the annihilation process.

30
Q

Physical half life of Tc-99m

31
Q

Physical half life of Iodine-123

32
Q

Physical half life of Xenon-133

A

125 hours

Note: The biological half life is 30 seconds (because it is breathed out).

33
Q

Physical half life of Thallium-201

34
Q

Physical half life of Indium-111

35
Q

Physical half life of Gallium-67

36
Q

Physical half life of Iodine-131

37
Q

Physical half life of Fluorine-18

A

110 minutes

38
Q

Physical half life of Strontium-89

A

50.5 days (14 days in bone)

39
Q

Physical half life of Samarium-153

40
Q

Physical half life of Radium-223

41
Q

Physical half life of Yttrium-90

42
Q

Physical half life of Rubidium-82

A

75 seconds

43
Q

Physical half life of Nitrogen-13

A

10 minutes

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