Gastrointestinal: Luminal, Stomach Flashcards
Think malignant ulcerated stomach cancer
Note: This is the Carmen Meniscus sign.
Think benign gastric ulcer
Note: There is a Hampton’s line (red arrows).
Gastric ulcer that is wider than it is deep, with nodular edges, and gastric folds adjacent to the ulcer…
Think malignant ulcerated cancer
Note: Look for Carmen Meniscus sign (highly suggestive of cancer).
Gastric ulcer that is deeper than it is wide, with sharp contour, and gastric folds radiating to the ulcer…
Think benign gastric ulcer
Note: Look for Hampton’s line (highly suggestive of benign ulceration).
What is the most common mesenchymal tumor of the GI tract?
Gastrointestinal stromal tumor (GIST)
What is the most common location for GIST?
Stomach (70%)
Note: Duodenum is the second most common.
What age group do GISTs occur in?
Older pts (rare before age 40)
Gastrointestinal stromal tumors are associated with…
- NF1
- Carney’s triad
Is lymphadenopathy common in GIST?
No
Where is the most common location for GIST metastases?
Liver
Note: Metastases are very uncommon (which is why lymphadenopathy is uncommon).
Carney’s triad
- Pulmonary chondroma
- Extra adrenal pheochromocytoma
- GIST
What is the most common gastric malignancy?
Adenocarcinoma (followed by lymphoma)
Note: Malignant GIST is very rare.
Risk factors for gastric adenocarcinoma
- H. pylori infection
- Older age
- Pernicious anemia
- Menetrier’s disease
- Prior gastroenterostomy (old treatment for peptic ulcer disease)
Metastatic spread of gastric adenocarcinoma to the ovary…
Krukenberg tumor
Gastric adenocarcinoma with a left supraclavicular mass…
Think metastatic spread to a left supraclavicular lymph node (Virchow node)
Appearance of GIST vs gastric adenocarcinoma on imaging
GIST is usually smoothly marginated and exophytic
Gastric adenocarcinoma is usually large, ulcerated, and heterogeneous asymmetric wall thickening
What are the major types of gastric lymphoma?
- Primary (MALT)
- Secondary (systemic lymphoma)
What is the most common extra nodal site for non-Hodgkin lymphoma?
The stomach
Which gastric cancer is most likely to cause a gastric outlet obstruction?
Adenocarcinoma (if in the gastric antrum)
Note: Lymphoma rarely causes gastric outlet obstruction.
Major complication of chemotherapy treatment for gastric lymphoma
Gastric perforation
Classic imaging appearance of gastric lymphoma
Diffuse gastric wall thickening (>1 cm) without gastric outlet obstruction
Note: It often crosses the pylorus.
Stomach metastases are most likely to be from what primaries?
- Melanoma
- Breast
- Lung
Note: Gastric metastases are very rare.
Linitis plastica
Diffuse infiltration of the gastric wall, creating a contracted stiffened appearance
Note: This is usually due to breast/lung metastases or gastric lymphoma.
Diffuse thickening of the gastric wall, suggestive of linitis plastica (think breast/lung mets or gastric lymphoma)
Multiple gastric ulcers with no duodenal ulcers…
Think chronic aspirin therapy
Note: Aspirin does not cause duodenal ulcers.
Multiple duodenal ulcers…
Think Zollinger-Ellison syndrome
Note: Most duodenal ulcers are solitary.
What is this gastric mucosal pattern called?
Areae gastricae (normal finding)
When does the normal areae gastricae mucosal pattern become enlarged?
- Elderly pts
- H. pylori infection
- Focally enlarged next to an ulcer