Nitro drip

Question 1

Class

Answer 1

Nitrate, coronary vasodilator, antianginal.

Question 2

Supplied

Answer 2

50 mg / 10 ml vial (5 mg/ml)

Question 3

Adult Dose

Answer 3

Hypertensive emergency / angina: Infusion 5 mcg/min IV, titrate up in 5 mcg/min increments every 5 minutes to a MAP reduction of 10% from baseline.

Pulmonary edema: Infusion 5 mcg/min IV.

Question 4

Max adult dose

Answer 4

BP should not be reduced more than 10% of initial MAP.

Question 5

Pediatric dose

Answer 5

Pulmonary edema: 0.5-20 mcg/kg/min IV.

Question 6

Max pediatric dose

Answer 6

60 mcg/kr/min

Question 7

Action

Answer 7

Vasodilating agent that allows for smooth muscle vasculature to dilate via the release of nitric oxide.

Question 8

Indication

Answer 8

Angina, hypertensive emergency, CHF, pulmonary edema.

Question 9

Contraindication

Answer 9

Recent use of sildenafil (Viagra) or vardenafil (Levitra), constrictive pericarditis, pericardial tamponade, restrictive cardiomyopathy, hypotension.

Question 10

Considerations

Answer 10

Use non-absorptive tubing

Do not lower BP > 10% MAP

Question 11

Side effects

Answer 11

CNS: Dizziness, headache.
CV: Syncope, hypotension, tachycardia