Labetalol Flashcards
1
Q
Brand name
A
Trandate
2
Q
Class
A
Beta adrenergic blocker with some alpha block effect.
3
Q
Suppled
A
100 mg/ 20 ml (5 mg/ml)
4
Q
Adult Dose
A
10-20 mg slow IV push over 2 min; doses can be repeated every ten minutes until the desired supine blood pressure is achieved.
5
Q
Max adult dose
A
300 mg
6
Q
Pediatric dose
A
Safety in children has not been established.
7
Q
Action
A
- Beta blockade leads to effects on SA and AV nodes, and ventricular muscle that leads to bradycardia, delay in AV conduction and depression of cardiac contractililty.
- Alpha blockade leads to vasodilation, decreased peripheral resistance, and orthostatic hypotension.
8
Q
Indication
A
Hypertensive emergencies (hypertension with evidence of end organ dysfunction: angina, CHF, stroke, renal failure) and pregnancy induced hypertension.
9
Q
Contraindications
A
Hypotensive/shock, CHF, 2 and 3 degree heart block, Asthma, Bradycardia, and any known drug interaction.
10
Q
Side effects
A
Bradycardia, Hypotension, Syncope, Dyspnea, Heart block, CHF, Dizziness, Bronchospasm.
