Diltiazam

Question 1

Drug Class

Answer 1

Slow Calcium Channel blocker / antagonist

Question 2

Description

Answer 2

slows conduction, increases refractories in AV node, cause coronary and peripheral vasodilation.

Question 3

Onset and duration.

Answer 3

Onset = 2-5min Duration = 1-3hr

Question 4

Indications

Answer 4

A-fib, A-flutter, Mutifocal atrial tachycardia, PSVT (Adensosine is the first choice for conversion of PSVT)

Question 5

Contraindications

Answer 5

Sick sinus syndrome, 2nd and 3rd degree heart block, Hypotension (systolic <100), A-fib or A-flutter with WPW syndrome or a short P-R interval, Currentt use of Beta blockers, V-tach, Acute MI.

Question 6

Side effects

Answer 6

1st and 2nd degree AV block, Bradycardia, Hypotension, CHF, Syncope, Ventricular dysrhythmias, N and V.

Question 7

Adult Bolus Dose

Answer 7

1st dose: 0.25mg/kg IV over 2 min.
2nd dose: Can repeat on 15 min 0.35mg/kg IV over 2 min.
2nd dose is indicated if no response to 1st dose.

Question 8

Adult Maintenance Infusion

Answer 8

Mix 125 mg in 100 ml of solution. Infuse at 5-15 mg/hr. Titrate drip rate to acceptable heart rate.

Question 9

Pediatric Dose

Answer 9

NOT FOR PEDS

Question 10

Additional Information

Answer 10

Do not administer in the same IV line as Furosemide without first flushing the line.

Question 11

Supplied

Answer 11

25 mg / 5 ml