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BB 3rd Edition > NHP pics and herpesviruses > Flashcards

NHP pics and herpesviruses Flashcards

1
Q
A

Human herpesvirus 1

Intranuclear inclusion body within the CNS of a common marmoset

nonsuppurative meningoencephalitis

HSV1 antigen with neurons

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2
Q
A

B virus - thin-walled vesicles at the commissures of the lips of a pig tail macaque

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3
Q
A

Multinucleated syncytial cells with intranuclear inclusions

Positive for alphaherpesvirus antigen

B virus

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4
Q
A

Simian varicella virus (Cercopithicine herpesvirus 9)

Cutaneous exanthema with blood filled vesicles

Vesicle within haired skin demonstrating multinucleated syncytia and intranuclear inclusions

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5
Q
A

RhCMV necrotizing colitis

Cytomegalic cell with large intranuclear inclusions and neutrophilic infiltrates

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6
Q
A

RFHV

Pleomorphic spindle cells within retroperitoneal fibromatosis

RFHV-infected cells demostrated by immunohistochemistry for latent nuclear antigen (LANA)

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7
Q
A

Samiri sp herpesvirus lesion

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8
Q
A

Samiriine herpesvirus 2: malignant lymphoma in the liver and spleen of an owl monkey

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9
Q
A

Adenoviral infections of the small intestine of a common marmoset demonstrating basophilic intranuclear inclusions within enterocytes of the villous tips and corresponding adenoviral antigen .

Hepatic necrosis with adenovirus intranuclear inclusions

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10
Q
A

Rhesus parvovirus

Intranuclear inclusions with erythroid precursors of bone marrow in a rhesus macaque

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11
Q
A

Measles virus viral examthema

Bronchointerstitial pneumonia in measles virus-infected macaque

Marked lymphoid depletion

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12
Q

Macacine herpesvirus 1

A

Host - macaque

Abbherent host - Human

Alphaherpesvirus

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13
Q

Cercopithecine herpesvirus 9

A

Unknown host

Alphaherpesvirus

Antibodies found in stumptail macaques (M. arctoides)

Varicellovirus (genus)

Vesicular dermatitis progressing to death within 48 hours (not hands or feet) in AGMs, Patas, and macaques

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14
Q

Papiine herpesvirus 2

A

Host = baboon

Common, subclinical, latent

Alphaherpesvirus

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15
Q

Cercopithecine herpesvirus 2 (SA8)

A

Host = C. aethiops (AGM)

Venereal transmission

Small vesicles, pustules on genitals

Alphaherpesvirus

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16
Q

Saimiriine herpesvirus 1

A

Herpesvirus tamirinus, Herpes T

Host = Squirrel monkey

Abherrent hosts: Owl monkey (Aotus), marmoset, tamarin

Vesicular oral/labial/dermal lesions (7-10 d), pruritis/anorexia/depression/death w/i 24-28 hours

Multinucleate giant cells in epidermis, INIB

ML vaccine can cause outbreaks

Alphaherpesvirus

17
Q

Human herpesvirus 1 and 2

A

Apes: usually self-limiting, fatal in gibbons

Owl monkey (Aotus), tamarin: Fatal disseminated dz similar to Samiirine herpesvirus 1

Facial lesions, blephritis, stomatitis, encelphalitis

ML vaccine protective

Alphaherpesvirus

18
Q

Human herpesvirus 3

A

Ape: mild, self-limiting dermatitis

Alphaherpesvirus

19
Q

Macacine herpesvirus 3

A

Rhesus CMV

Betaherpesvirus

Common, rarely overt dz

In macaques w/ SIV disseminated dz

Large cytomegalic cells with INIB and ICIB

20
Q

Lymphocryptovirus

A

Gammaherpesvirus

Subclinical infection common by 1 year

Co-infection with SIV = malignant B cell lymphoma, hairy oral leukoplakia

EBNA2 and BZLF1 proteins

21
Q

Rhesus rhadinovirus

A

Gammaherpesvirus

Infects CD20+ B cells

22
Q

Retroperitoneal fibromatosis associated herpesvirus

A

Gammaherpesvirus

Mesenchymal proliferative disease associated with SRV coinfection in macaques

23
Q

Herpesvirus saimiirine 2

A

Gammaherpesvirus

Rhadinovirus

Cross-species transmission to Callitrichids, Spider, Howler, and owl monkeys resutling in malignant lymphoma

24
Q

Herpesvirus ateles

A

Ateline herpesvirus 2 and 3

Gammaherpesvirus

Rhadinovirus

Cross species transmission to Callitrichids and owl monkeys resuling in rapid onset of malignant lymphoma

T cell origin

25
Q

Human herpesvirus 4

A

EBV

Gammaherpesvirus

Aberrhant host: NWMs

Asymptomatic or infection mononucleosis

26
Q

Paniine herpesvirus 1

A

Chimpanzee herpes

Gamma herpesvirus

Host: apes

27
Q

Pongiine herpesvirus 2

A

Orangutan herpes

Gammaherpesvirus

28
Q

Gorilliine herpesvirus 1

A

Gorilla herpes

Gammaherpesvirus

29
Q

Papiine herpesvirus 1

A

Herpes papionis

Gammaherpesvirus

Malignant lymphoma in baboons and macaques

30
Q

Cercopithecine herpesvirus 14

A

AGM EBV-like virus

Gammaherpesvirus

Found in Vervet

31
Q

Callitrichine herpesvirus 3

A

Marmoset lymphocryptovirus

Weight loss, inappetance and diarrhea, firm, mid-abdominal B-cell lymphoma

Gammaherpesvirus

BB 3rd Edition (19 decks)

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