NHP pics and herpesviruses Flashcards

1
Q
A

Human herpesvirus 1

Intranuclear inclusion body within the CNS of a common marmoset

nonsuppurative meningoencephalitis

HSV1 antigen with neurons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q
A

B virus - thin-walled vesicles at the commissures of the lips of a pig tail macaque

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q
A

Multinucleated syncytial cells with intranuclear inclusions

Positive for alphaherpesvirus antigen

B virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q
A

Simian varicella virus (Cercopithicine herpesvirus 9)

Cutaneous exanthema with blood filled vesicles

Vesicle within haired skin demonstrating multinucleated syncytia and intranuclear inclusions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
A

RhCMV necrotizing colitis

Cytomegalic cell with large intranuclear inclusions and neutrophilic infiltrates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q
A

RFHV

Pleomorphic spindle cells within retroperitoneal fibromatosis

RFHV-infected cells demostrated by immunohistochemistry for latent nuclear antigen (LANA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q
A

Samiri sp herpesvirus lesion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q
A

Samiriine herpesvirus 2: malignant lymphoma in the liver and spleen of an owl monkey

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
A

Adenoviral infections of the small intestine of a common marmoset demonstrating basophilic intranuclear inclusions within enterocytes of the villous tips and corresponding adenoviral antigen .

Hepatic necrosis with adenovirus intranuclear inclusions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q
A

Rhesus parvovirus

Intranuclear inclusions with erythroid precursors of bone marrow in a rhesus macaque

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q
A

Measles virus viral examthema

Bronchointerstitial pneumonia in measles virus-infected macaque

Marked lymphoid depletion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Macacine herpesvirus 1

A

Host - macaque

Abbherent host - Human

Alphaherpesvirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Cercopithecine herpesvirus 9

A

Unknown host

Alphaherpesvirus

Antibodies found in stumptail macaques (M. arctoides)

Varicellovirus (genus)

Vesicular dermatitis progressing to death within 48 hours (not hands or feet) in AGMs, Patas, and macaques

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Papiine herpesvirus 2

A

Host = baboon

Common, subclinical, latent

Alphaherpesvirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cercopithecine herpesvirus 2 (SA8)

A

Host = C. aethiops (AGM)

Venereal transmission

Small vesicles, pustules on genitals

Alphaherpesvirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Saimiriine herpesvirus 1

A

Herpesvirus tamirinus, Herpes T

Host = Squirrel monkey

Abherrent hosts: Owl monkey (Aotus), marmoset, tamarin

Vesicular oral/labial/dermal lesions (7-10 d), pruritis/anorexia/depression/death w/i 24-28 hours

Multinucleate giant cells in epidermis, INIB

ML vaccine can cause outbreaks

Alphaherpesvirus

17
Q

Human herpesvirus 1 and 2

A

Apes: usually self-limiting, fatal in gibbons

Owl monkey (Aotus), tamarin: Fatal disseminated dz similar to Samiirine herpesvirus 1

Facial lesions, blephritis, stomatitis, encelphalitis

ML vaccine protective

Alphaherpesvirus

18
Q

Human herpesvirus 3

A

Ape: mild, self-limiting dermatitis

Alphaherpesvirus

19
Q

Macacine herpesvirus 3

A

Rhesus CMV

Betaherpesvirus

Common, rarely overt dz

In macaques w/ SIV disseminated dz

Large cytomegalic cells with INIB and ICIB

20
Q

Lymphocryptovirus

A

Gammaherpesvirus

Subclinical infection common by 1 year

Co-infection with SIV = malignant B cell lymphoma, hairy oral leukoplakia

EBNA2 and BZLF1 proteins

21
Q

Rhesus rhadinovirus

A

Gammaherpesvirus

Infects CD20+ B cells

22
Q

Retroperitoneal fibromatosis associated herpesvirus

A

Gammaherpesvirus

Mesenchymal proliferative disease associated with SRV coinfection in macaques

23
Q

Herpesvirus saimiirine 2

A

Gammaherpesvirus

Rhadinovirus

Cross-species transmission to Callitrichids, Spider, Howler, and owl monkeys resutling in malignant lymphoma

24
Q

Herpesvirus ateles

A

Ateline herpesvirus 2 and 3

Gammaherpesvirus

Rhadinovirus

Cross species transmission to Callitrichids and owl monkeys resuling in rapid onset of malignant lymphoma

T cell origin

25
Q

Human herpesvirus 4

A

EBV

Gammaherpesvirus

Aberrhant host: NWMs

Asymptomatic or infection mononucleosis

26
Q

Paniine herpesvirus 1

A

Chimpanzee herpes

Gamma herpesvirus

Host: apes

27
Q

Pongiine herpesvirus 2

A

Orangutan herpes

Gammaherpesvirus

28
Q

Gorilliine herpesvirus 1

A

Gorilla herpes

Gammaherpesvirus

29
Q

Papiine herpesvirus 1

A

Herpes papionis

Gammaherpesvirus

Malignant lymphoma in baboons and macaques

30
Q

Cercopithecine herpesvirus 14

A

AGM EBV-like virus

Gammaherpesvirus

Found in Vervet

31
Q

Callitrichine herpesvirus 3

A

Marmoset lymphocryptovirus

Weight loss, inappetance and diarrhea, firm, mid-abdominal B-cell lymphoma

Gammaherpesvirus