Neurology (U.W.) Flashcards

1
Q

RETROgrade transport is mediated by which protein

A

Dyenin

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2
Q

ANTEROgrade transport is mediated by which protein

A

kinesin

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3
Q

symptoms of Fragile X syndrome

A

physical: long and narrow face with large chin and forehead and testes
neuro: speech/motor devptl delay in infancy
neuro/psych (ADHD/anxiety/autism) after puberty
* hyperlaxity of hand joints

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4
Q

symptoms of cerebellar hemisphere lesion

A

dysdiadochokinesia - prob w/ rapid alt movement
intention tremor
limb dysmetria - undershoot/overshoot

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5
Q

Rabies Encephalitis

A

(remember it starts with flu-like prodrome)

  • altered mental state ex: aggression
  • pharyngeal spasm leading to water avoidance
  • drooling and pupillary dilation
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6
Q

organic (methylmalonic or proprionic) acidemia - patients should avoid what?

A
  • odd chain fatty acid
  • Valine, Isoleucine, Methionine, Threonine
  • thymidine, uracil
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7
Q

what (2) pathological processes can cause lesions in basal ganglia/ thalamus/ deep nuclei

A
  • Charcot Bouchard aneurysms via hemorrhage (looks bright on CT)
  • lacunar stroke via ischemia (looks dark on CT)
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8
Q

What is the pathology (2) of lacunar stroke

A

(1) lipohyalinosis

(2) microatheroma

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9
Q

iliohypogastric N function

A

sensory to suprapubic and gluteal region

motor to abdominal wall muscles

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10
Q

Common Peroneal N injury

A

foot drop, steppage gate

location- head of fibula

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11
Q

Deep Peroneal N vs Superficial Peroneal N

A

Deep Peroneal - Dorsiflexion

Superficial Peroneal- Eversion, and sensory to shin and dorsum of foot

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12
Q

Buspirone

A

partial agonist of 5HT1A (serotonin)
used for GAD
non-sedating, non-addictive, no sexual dysfunction, action in 1-2 wk

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13
Q

what type of traumatic brain hemorrhage may not by symptomatic or visualized until weeks after

A

Subdural hematoma

-bc it is the tearing of bridgine veins, the blood flow may not initially present

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14
Q

how can you tell if allergy to one anesthetic will cause allergy to another

A

look at the class. amides Xreact with amides and esters w/ esters
amides have 2 i’s (lidocaine, bupivicaine)
esters have 1 i

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15
Q

what nerve goes through pronator teres

A

Median N

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16
Q

what nerve goes through coracobrachialis

A

Median N

17
Q

Subacute Sclerosing Panencephalitis is caused by?

A

Measles

18
Q

Tay Sachs signs and symptoms?

A

child born normally but exhibits motor and neuro delays at 3-6 months. seizures and cherry red spot. no hepatmegaly

19
Q

Negri bodies are seen in?

A

Rabies

20
Q

Lewy Bodies are seen in?

A

Parkinson’s and Lewy Body Dementia

21
Q

Medial Medullary Syndrome?

A

occlusion of Anterior Spinal A
- disruption of corticospinal tracts (m weakness), medial lemniscus (face/body sensation decreased) and deviation of tongue to affected side

22
Q

what antidepressant causes hypertension, diapphoresis, and tachycardia? what brings this on?

A

MAOi causing sympathetic crisis

due to ingestion of tyramine containing foods

23
Q

drug that helps ALS

A

Riluzole- blocks Glutamate