Neuro - FA Patho Eye/Ear p520 -531 Flashcards
Most common cause of conjunctivitis?
viral is most common, esp adenovirus
Extra ocular symptom of viral conjunctivitis?
swollen preauricular node
What is astigmatism?
Abnormal curvature of cornea –> different refractive power at different axes. Correct with cylindrical lens.
Why does presbyopia happen?
dec lens elasticity, changes in lens curvature, dec strength of ciliary m
Where is the light focused, in terms of retina, in the case of hyperopia and myopia?
In hyperopia, light focused behind retina, and in myopia light is focused in front of the retina
Presbyopia leads to an issue with ?
accommodation
Bacteria causing conjunctivitis?
H. influ, Chlamydia(follicular type), N gon
Causes of Neonatal conjunctivitis?
N. gonorrhea, HSV-1, Chlamydia - neonatal
Children - Measles ( the 3Cs coryza, conjunct., cough) Reactive arthritis.(Reiter syndrome)
What happens in cataracts
Painless, often bilateral, opacification of lens , often resulting in glare and dec vision, especially at night
long use of what drugs can lead to cataracts
excess alcohol use, or prolong corticosteroid use
Congenital risk factors of cataracts
classic galactosemia, galactokinase deficiency, trisomies (13, 18, 21), ToRCHeS infections (eg, rubella), Marfan syndrome, Alport syndrome, myotonic dystrophy, neurofibromatosis 2.
Optic disc atrophy with cupping?
Glaucoma
How does Diabetes lead to lens opacification?
Inc gluc in the lens –> sorbitol via aldose reductase, and also to fructose. Both fructose and sorbitol will stimulate water influx –> osmotic cell injury, lens becomes opaque
Open angle glaucoma is more common in which patient population?
African American
Cause of secondary closed angle glaucoma?
Hypoxia from retinal disease, like DB or vein occlusion - induces vasoproliferation in iris that contracts angle
halos, rock hard eye, frontal headache are symptoms of what
Glaucoma - acute closure
Chronic closure glaucoma - symptoms?
Mostly asymptomatic, but over time can lead to CN II issues, especially loss of periph vision
which ND is associated with early onset glaucoma?
Sturge Weber
explain the pathophysio behind early onset glaucoma in sturge weber
ipsilateral leptomeningeal angioma & episcleral hemangioma –> inc IOP –> early onset glaucoma
2ndary causes of open angle glaucoma
blocked trabecular meshwork from WBCs (eg, uveitis), RBCs (eg, vitreous hemorrhage), retinal elements (eg, retinal detachment).
Diseases associated with uveitis?
systemic inflammatory disorders - sarcoidosis, rhematoid arthritis, juvenile idiopathic arthritis, PAIR (HLA-B27) arthritides
Collection of pus in the anterior chamber is seen in ?
uveitis
What causes metamorphopsia and loss of central vision?
Age related macular degeneration - distortion and scotomas
In dry macular degeneration, what collects in the eye?
—Deposition of yellowish extracellular material (“Drusen”) in between Bruch membrane and retinal pigment epithelium
What makes wet macular degeneration wet - how to tx?
n due to bleeding 2° to choroidal neovascularization.
Treat with anti-VEGF (vascular endothelial growth factor) injections (eg, bevacizumab, ranibizumab).
What is seen in this picture? what are the arrows pointing to?
DB retinopathy
retinal hemorrhages
What is this a picture of?
What are the arrows pointing to?
HTN retinopathy
macular star = red arrow (exudate)
cotton wool spots = blue arrow
What is this a picture of?
Retinal v occlusion
arrows point to engorged veins and hemorrhage