Neuro - extra FA Pharm p532 - 539 Flashcards

1
Q

What primarily renal drug affects aq humor? how?

A

carbonic anhydrase inhibitors, dec formation

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2
Q

Which drug can lead to cataracts?

A

Long term corticosteroid use

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3
Q

Tx for Non-prolif DB retinopathy?

A

blood sugar control, surgery

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4
Q

Tx for Proliferative DB retinopathy?

A

Peripheral retinal photocoag, surgery, anti-VEGF (Bevacizumab)

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5
Q

Treatment for congenital chorioretinitis?

A

Sulfadiazine + pyrimethamine

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6
Q

Treatment for CMV retinitis?

A

Foscarnet, Cidofovir - if gancilovir fails

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7
Q

treatment of facial palsy

A

steroids, acyclovir

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8
Q

The drug that treats “1 Big Damn Headache” is contraindicated in which pts?

A

Triptans - 5-HT1B/1D agonists

patients with CAD or Prinzmetal angina

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9
Q

MOA of galantamine?

A

AChE Inhibitor

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10
Q

Which drug can be used both in Schizophrenia (primarily positive symptoms) and Huntington dz?

A

Haloperidol—D2 receptor antagonist

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11
Q

Tramadol
what is it?
and fatal side effect

A

Works on everything
Serotonin syndrome!!
also decreases seizures threshold

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12
Q

Migraine Prophylaxis?

A

BACT

Topiramate!

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13
Q

bipolar treatment

  1. manic phase
  2. depressed phase
A
  1. manic: carbamezepine

2. lamotrigine

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14
Q

if a drug has low potency, what characteristics does it have?

A

high MAC = low solubility in lipid

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15
Q

list properties of N2O in term of

  1. induction
  2. potency
A
  1. induction: rapid –> low blood solu

2. potency: low lipid solu –> low potency

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16
Q

what are ketamines?

A

arylcyclohexylamines ACHA

17
Q

this IV anesthetic is often used for outpatient quick and easy procedures like botox. K-pop stars favorites

A

propofol

18
Q

bad thing about propofol is there is pain at injection site, what would you use instead?

A

fospropofol

19
Q

whats contraindicated in porphyria?

A

Barbituates

20
Q

DMARDS for MS

A

IFNB and natalizumab

21
Q

what is natalizumab?

A

against integrin 4

22
Q

Whats the treatment of acute flares of MS

A

IV steroids

23
Q

can you use steriod in GB?

A

“Respiratory support is critical until recovery.
Additional treatment: plasmapheresis, IV
immunoglobulins. No role for steroids.”

24
Q

treatments for cluster headache?

A

100% O2, sumatriptan

25
Q

target of sumatriptan?

A

5HT 1B/1D agonist –> inhibit trigeminal nerve activation, vasoactive peptide release –> induces vasoconstriction

26
Q

4 DOC for migraine prophylaxis?

A

propranolol, topiramate, CCB, amitriptyline

27
Q

4 DOC for tension headache?

A

analgesics, NSAIDs, acetaminophen, amitriptyline for chronic pain

28
Q

DOC for glaucoma emergenices?

A

pilocarpine (very effective at opening meshwork into canal of Schlemm)

29
Q

what 2 opioids are used for diarrhea?

A

loperamide, diphenoxylate