Neuro - extra FA Pharm p532 - 539

Question 1

What primarily renal drug affects aq humor? how?

Answer 1

carbonic anhydrase inhibitors, dec formation

Question 2

Which drug can lead to cataracts?

Answer 2

Long term corticosteroid use

Question 3

Tx for Non-prolif DB retinopathy?

Answer 3

blood sugar control, surgery

Question 4

Tx for Proliferative DB retinopathy?

Answer 4

Peripheral retinal photocoag, surgery, anti-VEGF (Bevacizumab)

Question 5

Treatment for congenital chorioretinitis?

Answer 5

Sulfadiazine + pyrimethamine

Question 6

Treatment for CMV retinitis?

Answer 6

Foscarnet, Cidofovir - if gancilovir fails

Question 7

treatment of facial palsy

Answer 7

steroids, acyclovir

Question 8

The drug that treats “1 Big Damn Headache” is contraindicated in which pts?

Answer 8

Triptans - 5-HT1B/1D agonists

patients with CAD or Prinzmetal angina

Question 9

MOA of galantamine?

Answer 9

AChE Inhibitor

Question 10

Which drug can be used both in Schizophrenia (primarily positive symptoms) and Huntington dz?

Answer 10

Haloperidol—D2 receptor antagonist

Question 11

Tramadol
what is it?
and fatal side effect

Answer 11

Works on everything
Serotonin syndrome!!
also decreases seizures threshold

Question 12

Migraine Prophylaxis?

Answer 12

BACT

Topiramate!

Question 13

bipolar treatment

1. manic phase
2. depressed phase

Answer 13

1. manic: carbamezepine

2. lamotrigine

Question 14

if a drug has low potency, what characteristics does it have?

Answer 14

high MAC = low solubility in lipid

Question 15

list properties of N2O in term of

1. induction
2. potency

Answer 15

1. induction: rapid –> low blood solu

2. potency: low lipid solu –> low potency

Question 16

what are ketamines?

Answer 16

arylcyclohexylamines ACHA

Question 17

this IV anesthetic is often used for outpatient quick and easy procedures like botox. K-pop stars favorites

Answer 17

propofol

Question 18

bad thing about propofol is there is pain at injection site, what would you use instead?

Answer 18

fospropofol

Question 19

whats contraindicated in porphyria?

Answer 19

Barbituates

Question 20

DMARDS for MS

Answer 20

IFNB and natalizumab

Question 21

what is natalizumab?

Answer 21

against integrin 4

Question 22

Whats the treatment of acute flares of MS

Answer 22

IV steroids

Question 23

can you use steriod in GB?

Answer 23

“Respiratory support is critical until recovery.
Additional treatment: plasmapheresis, IV
immunoglobulins. No role for steroids.”

Question 24

treatments for cluster headache?

Answer 24

100% O2, sumatriptan

Question 25

target of sumatriptan?

Answer 25

5HT 1B/1D agonist –> inhibit trigeminal nerve activation, vasoactive peptide release –> induces vasoconstriction

Question 26

4 DOC for migraine prophylaxis?

Answer 26

propranolol, topiramate, CCB, amitriptyline

Question 27

4 DOC for tension headache?

Answer 27

analgesics, NSAIDs, acetaminophen, amitriptyline for chronic pain

Question 28

DOC for glaucoma emergenices?

Answer 28

pilocarpine (very effective at opening meshwork into canal of Schlemm)

Question 29

what 2 opioids are used for diarrhea?

Answer 29

loperamide, diphenoxylate