Neuro - Auditory System Flashcards
How many sections is the ear generally divided into?
→ outer
→ middle
→ inner
Where is the auditory organ located?
embedded in the petrous portion of the temporal bone (hardest bone in body)
What are the functions of the outer ear?
→ captures sound and focuses it in the tympanic membrane
→ amplify some frequencies by resonance in the canal
→ protect ear from external threats (done by hair and wax)
What are the functions of the middle ear?
amplification by:
→ focusing vibrations from large surface area (tympanic membrane) to smaller surface area (oval window). The change in surface area means the pressure is increased.
→ Using leverage from the incus-stapes joint to increase the force on the oval window
What is the hearing part of the inner ear?
cochlea
What is the function of the inner ear?
→ transduce vibration into nervous impulses
→ produces a frequency (or pitch) and intensity (or loudness) analysis of sound
What are the 3 compartments of the cochlea when it’s uncoiled?
→ scala vestibuli
→ scala media
→ scala tympani
What are the scala vestibuli and scala tympani?
bone structures, contain perilymph (high in sodium)
What is the scala media?
→ membraneous structure that contains endolymph (high in potassium)
→ contains the hearing organ / Organ of Corti
→ sandwiched between scala vestibuli and tympani
What membrane contains the organ of Corti?
basilar membrane
How is the basilar membrane arranged?
→ arranged tonotopically (thicker in one end, thinner the other) like a xylophone
→ base = narrow + tight
→ apex = wide + loose
→ sensitive to different frequencies at different points along length
What are the two types of hair cells in the Organ of Corti? How are they arranged?
→ inner hair cells, arranged in 1 column
→ outer hair cells, arranged in 3 columns
What is the purpose of the tectorial membrane in the Organ of Corti?
→ located above the hair cells
→ always in constant contact w OHCs, which assist in contact with IHCs
→ allows for hair deflection
→ this depolarises the cells
What are the functions of IHCs?
→ carries 95% of afferent info of the auditory nerve
→ transduces sound into nerve impulses
What are the functions of OHCs?
→ carries 95% of efferent info of the auditory nerve
→ modulates sensitivity of the response
What are the hairs of the hair cells called?
stereocilia
What does deflection of the stereocilia do?
→ mechanically opens the potassium open channels
→ ionic interchange = depolarisation of cell
→ neurotransmitter is liberated
How does amplitude of sound affect deflection?
higher amplitudes (louder sounds) causes greater deflection of stereocilia, more hair cells involved, etc.
What does hyper-polarisation of hair cells cause?
closes potassium channels
What is the auditory pathway from cochlea to cerebral hemispheres?
→ spiral ganglions form each cochlea project via auditory vestibular nerve (VIII) to ipsilateral cochlear nuclei (monoaural neurones)
→ auditory info crosses at the superior olive level in brainstem
→ after this point, all connections are bilateral
→ goes through inferior colliculus and medial geniculate body in thalamus
→ ends in auditory cortex
What happens if a sound is too soft to cause deflection?
OHCs contract to bring the tympanic membrane closer to the stereocilia of the IHCs to cause deflection so sound can be heard
What happens if a sound is too loud?
→ OHCs can elongate
→ pushes tympanic membrane away from stereocilia of IHCs
→ less deflection = less loud sound transduced
How is hearing arranged in the auditory cortex?
→ tonotopically organised (like a xylophone)
→ low freq to high freq anterior-posteriorly in the brain
What is frequency / pitch? What is it measured in?
→ cycles per second, perceived tone
→ measured in Hertz