Neuro 2 final Flashcards

(398 cards)

1
Q

Where are globular bushy cells located?

A

posterior ventral nucleus

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2
Q

Where are spherical bushy cells located?

A

anterior nucleus

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3
Q

What do bushy cells relay?

A

frequency

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4
Q

What is the ratio of bushy cells to hair cells in the cochlea?

A

1:1

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5
Q

Where are octopus cells located?

A

dorsal/ventral cochlear nuclei

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6
Q

What do octopus cells detect?

A

interval between frequencies

SPECIFICALLY ONSET AND DURATION

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7
Q

Where do octopus cells send axons?

A

anterior nucleus of the LL

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8
Q

Multipolar cells send information about?

A

intensity

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9
Q

the superior olive detects what?

A

localization of sound and intensity differences from side to side

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10
Q

time lag is

A

interaural time

localizing sound in space; comparing one side to the other

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11
Q

interaural time is the responsibility of what structure?

A

SO

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12
Q

The medial SO has what cells?

A

bipolar

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13
Q

the medial SO detects

A

time lag

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14
Q

the medial SO detects frequencies best

A

< 3 KHz

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15
Q

signals from the ipsilateral side are

A

excitatory

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16
Q

signals from the contralateral side are

A

inhibitory

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17
Q

Where does the medial SO receive axons from?

A

anterior ventral cochlear nucleus (bilateral)

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18
Q

What does the lateral SO detect

A

differences in intensity

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19
Q

the lateral So works best at what frequency?

A

> 2-3 KHz

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20
Q

What nuclei does the IC have

A

central, pericentral, external

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21
Q

the LL goes to what nucleus in the IC?

A

central

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22
Q

Some axons from the LL don’t make it to the ipsilateral central nucleus of the IC, where do they go?

A

cross to the other side via the posterior commissure of probst

the go to contralateral central nucleus of the IC or posterior nucleus of the LL

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23
Q

The axons from the posterior nucleus of the LL have what neurotransmitter?

A

GABA

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24
Q

Where does the central nucleus of the IC recieve axons from?

A

LL

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25
Where do the axons from the central nucleus of IC go?
anterior part of MG via brachium of IC
26
Where does the MG send signals to?
area 41 (specific thalamic nucleus)
27
What are the 2 main functions of the central nucleus?
1. interaural time | 2. some intensity of sound
28
What responds to intesity of sound?
1. multipolar cells 2. SO lateral 3. central nucleus of the IC
29
T or F | pericentral and external nuclei are non-specific?
T
30
What is the pericentral pathway?
pericentral---->area 42------>back to superior colliculus
31
The axons returning to the deep SC allow participation in what>?
orientation reflex
32
the deep SC send what tracts to participate in the orientation reflex?
tectospinal (neck mm) tectomesencephalic/tectopontine (extrinsic eye mm)
33
what is the pathway of the external nucleus of the IC?
external nucleus of IC----->medial MG (large)----->area 42
34
Neurons of the MG respond to what?
combinations of frequency (not individual) time intervals between frequencies (speech)
35
Where does the anterior MG receive from?
central nucleus of the IC
36
Where does the medial MG receive from?
external nucleus of IC & SPINAL CORD AND DCNs DIRECTLY
37
Where does the posterior MG receive from?
pericentral nucleus
38
Area 41 is broken into what?
isofrequency columns
39
area 41 responds to
timing and frequency
40
What is the pathway of area 41/42?
area 41/42----->area 22---->area 39/40------>area 44/45 (Broca's= area 44)
41
T or F | Area 41 is made of slabs of cells with concurrent function.
F | alternating
42
The second letter in the isofrequency column refers to....
ipsillateral side (sometimes inhibitory)
43
The first letter in the isofrequency column refers to....
contralateral side (always excitatory)
44
If Broca's area is destroyed, what happens?
you can hear and understand, but are unable to articulate anything in order to respond
45
Wernicke's area is responsible for?
semantic speech
46
What happens if Wernicke's is destroyed?
everything sounds like gibberish
47
What layer of the retina converts to electrical signal?
layer 2
48
What makes up the outer layer of the eye?
sclera and cornea
49
What makes up the middle layer of the eye?
choroid + ciliary body/mm + iris
50
What layer of the retina is the furthest back?
1
51
Where are photoreceptors found?
layer 2
52
What is the area in layer 2 where photoreceptors are concentrated?
macula
53
Where are the cell bodies for the photoreceptors found?
layer 4
54
Where is light focused at in the retina?
fovea
55
The fovea is made entirely of
cones
56
The center of the fovea is known as
foveola
57
After the light goes to layer 2, it then travels to where?
ganglion cells of layer 8
58
The ganglion cells of layer 8 then send to
CN II
59
Where does CN 2 exit the eye?
optic disk
60
T or F | there are photoreceptors in the optic disk.
F
61
Layer 1 of the retina is known as
pigment epithelium
62
Layer 1 function
prevents light from scattering; also stores vitamin A
63
Layer 2 contains ________; which are specialized endings of _________
photoreceptors; dendrites
64
rods detect ______ | cones detect _______
rods- black and white | cones- color
65
T or F cones work better in low light situations.
F
66
Rods and cones operate on the basis of
receptive fields
67
T or F | As you move away from the fovea cone concentration increases.
F
68
What is used for peripheral vision?
rods
69
What is used for night vision?
rods
70
What pigment do rods contain?
rhodopsin
71
What do rods release in the abscence of light?
glutamate
72
T or F | Glutamate released from the rods is inhibitory.
T
73
What increases when in the dark?
cGMP increases causing a Na+ influx this causes a release of glutamate turning the bipolar cell off
74
How is glutamate released in the dark?
tonically
75
What happens when light hits rods?
activates Rhodopsin------>break down cGMP----> decrease Na+------->decrease glutamate----->bipolar is on
76
Cones are described as _______cells
photopic
77
What do long-wavelength cones detect?
red
78
What do medium-wavelength cones detect?
green
79
What do short-wavelength cones detect?
blue
80
What is deuteranopia?
green-blind-----brown/gray apperance
81
What is Deuteranomaly?
green-defiecient------must be bright for detection
82
What is achromatic vision?
colorblindness
83
What is the ratio of rods to ganglion cells?
10:1
84
What is the ratio of cones to ganglion cells?
1:1
85
What layer mediates these connections?
layer 6
86
Layer 6 is made up of what cells?
horizontal/amacrine
87
Horizontal cells detect what?
changes between dark and light
88
Amacrine cells detect?
change in the change from dark to light
89
Ganglion cells are found in
layer 8
90
How many ganglion cells per side are there?
900K- 1.2 Million
91
Where is the optic disk located?
15 degrees nasal to the fovea
92
Why dont we notice this in our visual field?
Gestalt closure principle-------filling escatoma
93
What are the types of ganglion cells?
1. M (y) 2. P (x) 3. W
94
What type of ganglion cell does not use a center surround fashion?
W
95
M (y) ganglion cells recieve mostly from?
rods
96
M (y) cells detect
movement and contrast
97
M (y) are large cells and only do
black/white
98
P (x) receive from ________and detect
cones; color
99
P (x) have _______ receptor fields
small
100
W ganglion cells have slow conduction and go to the
SC and pre-tectal nucleus
101
W cells respond to
general images of light/dark
102
T or F | Upper/Lower visual fields swap, so images are projected upside down on the retina.
T
103
The upper visual field projects where?
lower LG
104
The upper visual field loops around ________, this is called what?
the temporal lobe, | meyer's loop
105
Where does the lower visual field project?
dorsal LG
106
How much of the visual cortex does the macular visual field occupy?
50%
107
Where do all visual fields project?
layer IV of area 17
108
Where is the primary visual cortex most concentrated?
calcarine fissure
109
How many layers make up the LG?
6
110
Which layers of the LG are magnocellular?
1 and 2
111
Where do layers 1 and 2 receive from, and what do they detect?
receive from M (y); | movement and contrast
112
What layers are parvicellular? Where do they receive from?
layers 3-6; | P (x)
113
What do layers 3-6 detect?
detail, color, and shape
114
T or F | In the LG the layers receive either ipsilateal or contralateral ganglion cells, there is an alternating pattern.
T
115
What is area 17 AKA?
striate cortex
116
What is the bright white band of axons in layer 4 of area 17 called?
band of Gennari
117
T or F | Receptive fields in the LG are oval shaped and stellates in layer 4 have their own receptive fields.
F | round receptive fields
118
The stellates in layer 4 of area 17 have this kind of receptive field.
elongated receptive fields with center-surround
119
T or F | There is a 1:1 ratio of LG axons to cortical cells.
F | a convergence of many LG axons to a cortical cell
120
Cortical receptive fields respond to ______ of light.
bars
121
What do these bars end up representing?
a single continuous shape by connecting the contour of the bars of light
122
What are the alternating pattern of contra/ipsi parts known as in area 17?
ocular dominance columns
123
What is the only termination point of the LG in the cortex?
layer 4 of area 17
124
The other layers of area 17 receive from where?
layer 4 of area 17
125
What is found perpindicular to the ocular dominance columns?
orientation columns
126
which cells have the elongated fields?
orientation columns
127
What are the cells of the orientation columns known as?
simple cells
128
Moving away from layer 4 the cells become _______
complex cells (layers 2,3,5,6)
129
Describe complex cells receptive fields.
A convergence of the fields from layer 4
130
What do complex cells lose because of the convergence of fields?
center-surround
131
T or F | Complex cells are orientation specific and pick up movement/direction.
T
132
What are blobs?
clusters of cells between the columns; primarily respond to color.
133
Where do blobs receive from?
LG
134
Do blobs have on/off capability?
no
135
Are blobs layer-specific?
no
136
T or F | Areas 18/19 are made of simple, complex, and hypercomplex cells.
F | no simple cells
137
How many pathways leave area 17?
2 streams of the visual cortical pathway
138
What are the two streams of the visual cortical pathway?
``` Dorsal pathway (parietal) Ventral pathway (temporal) ```
139
Where does the parietal stream terminate?
posterior parietal area (7a)
140
What does the dorsal stream receive signals from and what do they detect?
M (y) ganglion cells; | motion, contrast, and localization
141
Which stream deals with where something is and if it is moving?
dorsal
142
Where do signals pass through to get to the PPA?
mid-temporal area
143
Where does the temporal stream terminate?
inferior temporal area (37)
144
Where does the ventral stream receive signals and what do they deal with?
P (x) ganglion | form/shape +color/detail
145
What is achromotopsia?
a form of colorblindness; | trouble with interpretaion of colors; everything is gray
146
What is prosopagnosia?
loss of ability to recognize form (area 17) inability to recognize people by their face/ only physical features
147
What are the two ocular movements for visual tracking?
saccades + smooth pursuit
148
What are saccades?
sudden jerking movement of the eyes
149
What is the purpose of saccades?
to bring objects into the fovea for focus can do up to 700 degrees per second
150
What is smooth pursuit?
following a moving object
151
How fast does smooth pursuit track?
30 degrees a second (much slower)
152
Which ocular movement involves the vestibular apparatus?
smooth pursuit
153
What does PPRF stand for?
paramedian pontine reticular formation
154
What is the PPRF's function?
horizontal gaze center
155
What activates the PPRF?
the SC
156
If the ipsilateral lateral rectus muscle contracts, what must the contra do?
relax
157
What happens during staring?
SNr shuts of the SC; which in turn shuts down the PPRF so no visual tracking occurs
158
Does the SC normally have the SC tonically inhibited?
yes, until ready to visual track something
159
What is the island of reil?
insula; | island of neocortical tissue formed by deep invagination of the lateral fissure
160
What is the external capsule?
the area between the claustrum and puatmen
161
The external capsule is made of?
white matter
162
The extreme capsule is...
the area between the claustrum and neocortex
163
What does the limbic system deal with?
emotional circuitry and memory
164
What types of memory does the limbic system deal with?
short-term, spatial, emotional
165
How does memory strengthen?
by repetition....strengthening of synapses
166
T or F | The thalamus is a major output of the limbic system?
F | hypothalamus
167
What are the classifications of memory?
implicit/non-declarative | explicit/declarative
168
Implicit/non-declarative memory is what>?
implicit awareness; the subject is not aware they are learning
169
What 3 classificatins fall under implicit memory?
motor emotional working
170
What is motor memory?
how you do things
171
Motor memory is primarily in
cerebellum
172
What is emotional memory?
processing and storing emotional memory, especially negative emotions
173
Where is emotional memory primarily achieved?
amygdala
174
What is working memory?
holding something in your memory until you are done with it
175
Where is working memory primarily achieved?
pre-frontal cortex
176
What is explicit/declarative memory?
verbal; you know you are learning or memorizing something
177
What are the categories explicit memory?
immediate (sensory) short-term long-term
178
The immediate memory lasts?
only a few seconds
179
Short-term memory lasts?
minutes to days
180
Short-term memory usually cant do more then how many items? What does it use?
7 | hippocampus
181
Where does long-term memory take place?
neocortex
182
What is long-term based off?
Long-Term Potentiation
183
What does LTP involve?
glutamate
184
What principal is involved in long term memory?
Hebb; | increase synaptic strength through repetition
185
What is consolidation?
turning short-term into long-term.......mostly happens at night
186
What is spatial memory?
ability to tell where things are in space
187
Sense of direction is a responsibity of the
hippocampus (place cells)
188
Damage to the hippocampus disrupts?
loss of short-term; loss of new long-term = Alzheimer's
189
How long before Alzheimer's symptoms occur can the ____________ be damaged?
2 years | nucleus of meynert
190
What are ways to increase memory?
repetition emotional component relating understanding
191
What are the two sets of studies/experiments on the limbic system?
Kluver-Bucy | Circuit of Papez
192
What is Kuver-Bucy?
a result of bilateral damage to the amygdala, they found a set of 5 traditional symtoms collectivly known as Kluvaert-Bucy syndrome
193
What are the 5 symptoms of Kluver-Bucy
1. psychic blindness 2. hyperactivity 3. hyperorality 4. hypersexuality 5. emotional changes---fearful or aggressive
194
What is the archicortex?
3 consecutive layers of cells | neocortex=6
195
What is the hippocampal formation?
hippocampus + dentate gyrus + subiculum
196
T or F | the dentate gyrus and hippocampus both archicortices?
T
197
hippocampus AKA
Ammon's Horn
198
How many parts make up the hippocampus?
4
199
How many layers of cells does the subiculum normally have?
4 or 5======not 3 or 6
200
What is the fornix?
tracts leaving the hippocampus/dentate gyrus
201
What is the alvus?
starting point of axons
202
What is the crus?
where the axons thicken
203
What is the body of the fornix?
the tapered end
204
Where does the pre-commissural fornix terminate?
in the septal nuclei
205
Where does the post-commissural fornix terminate?
MB
206
What are the three septal nuclei?
1. Septum pellucidum 2. lateral septal nucleus 3. medial septal nucleus
207
Trace the pathway of the posterior column of the fornix.
PC of fornix----->MB------>AD/AV/AM------->cingulate gyrus
208
What part of the circuit of papez did papez not discover?
the afferents of the hippocampus
209
The endorhinal cortex receives from where?
cingulate gyrus | pyriform cortex
210
The endorhinal sends to?
subiculum | then on to the hippocampus, closing the circuit
211
The rhinal fissure is where?
seperating the primative olfactory region from the non-olfactory region
212
What does the rhinal fissure mark?
the border between the neocortex and the areas medial to it.....namely the pyriform cortex
213
What is the parahippocampal gyrus?
mass of cortical tissue surrounding the hippocampus
214
What is the anterior swelling of the parahippocampal gyrus?
uncus
215
What is the limbic lobe?
a "C" shaped structure made up of: cingulate +parahippocampal gyrus
216
Where does the parahippocampal gyrus terminate?
rostrally in the uncus
217
T or F the entohinal cortex is part of the parahippocampal gyrus?
T`
218
Where does the pyriform cortex receive from?
cingulate gyrus
219
Where does the pyriform cortex send to?
entorhinal cortex
220
What does the anterior commissure connect?
one olfactory bulb to the other
221
T or F | Olfaction is strongly tied to emotions and memory?
T
222
What loop sends axons to the hippocampus to feed vision into emotional circuitry?
Meyer's loop
223
In alzheimer's disease damage begins where, and goes to where?
hippocampus | neocortex
224
What are accessory limbic structures? Are they considered part of the limbic system?
olfactory bulb, Pre-Frontal Cortex, parahippocampal gyrus, and nucleus acumbens
225
Where are negative emotions?
amygdala
226
Where are positive emotions?
septal nuclei and nucleus acumbens
227
What structures from the diencephalon are from the limbic system?
anterior thalamic nuclei | hypothalamus
228
What structures from the telencephalon are part of the limbic system?
hippocampus/denate?subiculum/ amygdala septal nuclei cingulate gyrus
229
What is the amygdala?
the core of the limbic system
230
The amygdala processes emotional memory and is chief processor of ________ _____
negative emotions
231
What are the three divisions of the amygdala?
CM (corticomedial) BL (basolateral) Ct (central)
232
T or F | the BL amygdala is closest to the neocortex?
F | CM amygdala
233
T or F | The BL amygdala is a continuation of the claustrum?
T
234
Where does the posterior column terminate specifically?
medial mamillary body
235
Where does the endorhinal cortex receive from specifically?
lateral MB
236
The thalamic tubercle receives from where?
hippocampus directly and indirectly from MB
237
What are the afferents of the amygdala?
1. olfactory bulb to CM amygdala | 2. pyriform cortex to BL amygdala
238
What are the efferents of the amygdala?
all 3 regions of the amygdala send to nucleus acumbens | each region has their own efferents
239
What are the efferents of the CM amygdala?
1. PVN 2. preoptic 3. VM nuclei (hypothalamus) 4. septal nuclei
240
What is the CM amygdala and the septal nuclei connection an example of?
negative and positive emotions being linked
241
Pre-optic nucleus supplies....
testosterone
242
VM supplies....
estrogen also satiety center
243
PVNmc supplies....
oxytocin and ADH vasopressin
244
PVNpc supplies?
TRH & CRH
245
The CM amygdala coordinates.....
olfactory signal with sexual and feeding behavior
246
The BL amygdala sends to
1. MD (thalamus) 2. nucleus of Meynert 3. PFC
247
All the efferents of the CM amygdala make up what tract?
stria terminalis
248
T or F | The PFC receives from the amygdala directly from the MD and indirectly by bypassing the thalamus.
F | it bypasses the thalamus in the direct pathway and indirectly signals through the MD
249
The BL amygdala is responsible for two things....
1. interpretation of emotion | 2. coordinates a mental response to the emotional situation
250
The central nucleus is a ______ ______ ______ which means it is always listening.
2 way street
251
The Ct amygdla sends to what places?
1. n. tractus solitarius and parabrachialis 2. motor nucleus of 5 and CN 7 3. DMn of 10 and nucleus ambiguus 4. lateral hypothalamus (1 way street) 5. RVLM (rostral ventral lateral medulla)
252
What does the efferent to the n. tractus solitarius and parabrachialis influence?
blood pressure and breathing (emotional)
253
What does the efferent to the motor nucleus of 5 and CN 7 influence?
masseter and mm. of facial expression (emotion)
254
What does the efferent to the DMn of 10 and N. ambiguus influence?
digestion and excretion (emotion parasympathetic)
255
What does the efferent to the lateral hypothalamus influence?
symapthtic emotional influence (1-way)
256
What does the efferent to the RVLM influence?
sympathetic hub.....direct to lateral horn
257
The efferents of the BL amygdala and the Ct amygdala make up what?
Ventro-amygdalofugal pathway
258
What does the lateral fissure seperate?
frontal/parietal lobes from temporal lobe
259
What the central fissure separate?
frontal from parietal
260
What does the calcarine fissure separate?
nothing, deep medial surface fissure
261
What does the rhinal fissure separate?
inferior temporal gyrus from parahippocampal gyrus on medial side
262
What is the order of sulci, fissures, and gyri starting with pre-central sulcus?
1. pre-central sulcus 2. pre-central gyrus 3. central fissure 4. post-central gyrus 5. post central sulcus
263
post-central gyrus AKA
anterior parietal lobule
264
What areas form the anterior parietal lobule?
3,1,2 and 43
265
Areas 3,1,2 AKA
primary somatosensory cortex
266
T or F | the map of the body in the somatosensory cortex is ipsilateral and upside down.
F | It is contralateral and upside down
267
What is comitted the largest areas in 3,1,2?
face and hands lips more specifically
268
T or F | Area 43 is contralateral and is not upside down. (referring to body map)
F | it is bilateral and NOT upside down
269
What is space alotted based on?
size of area; not importance
270
T or F | Area 43 has a gustatory and slow pain function.
T | a small part for gustation and retroinsular for slow pain
271
Area 5/7 receives from
LP of thalamus
272
Area 41/42 (heschl) optimal frequency
800-3500 Hz
273
Area 17 location
upper and lower lip of the calcarine fissure
274
50% of Area 17 is
the representaion of the fovea
275
Area 18/19 surrounds area ____ and receives from
17; | pulvinar
276
Area 4 aka
primary motor area
277
area 4 location
frontal lobe
278
area 4 mainly for
individual muscles
279
area four concentration
distal extremities
280
T or F | Area 4 focuses more on the hand than the face as in Area 3,2,1.
T
281
What is the main area in area 4 concerning the face?
tongue
282
T or F | Area 4 is bilateral somatotopic map.
F | contralateral
283
What area is in front of area 4?
Area 6
284
T or F | Both the medial and lateral area 6 have complete somatotopic maps.
T
285
Area 6L is known as
pre-motor area
286
Area 6L controls
axial and proximal limb musculature | setting the posture of movement pre-motor
287
Area 6M is known as
supplementary motor area
288
Area 6M function
helps to assemble a sequence of movements | intentional preparation
289
What is the Pathway for mm movement?
PFC------>6M (SMA)----->area 4 and 6L------>corticospinal tract ------>laminae 9---------->skeletal mm
290
Area 8 is for
frontal eyefield or voluntary eye movements; visual tracking
291
T or F | visual tracking is a voluntary movement
F
292
What layer of the neocortex is well developed in sensory areas?
layer 4
293
What layer of the neocortex is well developed in motor areas?
layer 5
294
Name the 6 layers of the neocortex.
1. molecular layer 2. external granular layer 3. external pyramidal 4. internal granular layer 5. internal pyramidal 6. multiform layer
295
What layer is the outer band of baillarger in?
layer 4
296
What layer of the neocortex contains medium and large pyramidal cells?
layer 5
297
What layer receives the specific thalamic nuclei?
layer 4
298
What layer is mostly stellate cells?
layer 4
299
What layer of the neocortex contains very few neurons?
layer 1
300
What connects layer 3 to layer 2?
corticocortico axons
301
corpus callosum aka
interhemispheric commisure
302
What does the frontooccipial longitundinal fasiculus hook up?
visual areas to PFC
303
What does the uncinate fasiculus hook up?
anterior temporal lobe to PFC
304
what are the main areas associated with the term uncommitted cortex?
Areas 5 and 7
305
What is Broca's area?
Area 44 on left=motor speech
306
Broca's area does what in speech?
connecting phonemes of speech not mm. movement
307
What does damage to left area 44 cause?
Broca's aphasia (difficulty with speech articulation
308
Area 44 on the right is used for?
spatial perception
309
What is Wernicke's area?
22 main | 39/40
310
Area 22 aka
superior temporal gyrus
311
area 39 aka
angular gyrus
312
area 40 aka
supramarginal gyrus
313
area 39 function
supports reading, calculations, etc
314
What does Wernicke's area on the left do?
semantic speech (meaning)
315
What is Wernicke's aphasia and what side being damaged to cause?
no trouble speaking, but speech makes no sense left
316
What is the right side of Wernicke's area involved in?
prosody (non-verbal aspect of speech)
317
What does damage to the right side of Wernicke's area cause?
aprosodia | failure to pick up non-verbal clues of speech
318
What is aphasia?
inability to speak
319
What is apraxia?
inability to write
320
What is amusia?
can't pick up music----only noise
321
What is agnosia?
loss of sensory knowledge "not-knowing"
322
What is prosopagnosia, and what causes it?
failure to recognize people by their face; damage to inferior temporal region (area 37 and fusiform gyrus)
323
What is asomatognosia and what causes it?
a failure to recognize your own body from damage to right inferior parietal region (usually)
324
What is the last part of the brain to myelinate?
PFC
325
What layers are most well-developed in the PFC?
2 and 3
326
The PFC has a strong connection with what system?
limbic
327
What does the PFC work with?
storing-working memory and retrieving other memory
328
What does the orbitofrontal PFC specialize in?
motivation, socialization and emotional control
329
What does the dorsal PFC specialize in?
matching, decision making, and prediction (prognostication)
330
The left side of the brain has what characteristics?
1. more blood supply 2. tends to be more analytical 3. sequential 4. detailed considered scientific
331
What are the characteristics of the right side of the brain?
1. intuitive 2. holistic 3. parallel (many thoughts at the same time) considered creative
332
T or F | In regards to ascending spinal tracts, short tracts are confined to the spinal cord.
T | interspinal/intersegmental
333
Long ascending spinal tracts do what?
connect the spinal cord to something above like the brain
334
What are the neuron bodies of the DCs?
DRGs
335
What does the DC/ML system carry?
2 pt touch, proprioception, pressure and also tactile vibration
336
T or F | The DC/ML system is the only system to relay tactile vibration.
T
337
Where are the destinations for the DC/ML system?
conscious-area 3,1,2 | unconscious- cerebellum
338
Where does gracilis bring sensation from?
lower body (foot, leg, etc.) more medial
339
Where does cuneatus bring sensation from
from upper body (gets larger above T6)
340
At T1 which is larger cuneatus or gracilis?
cuneatus
341
After the ML decussation where is cuneatus located?
Lateral to gracilis
342
T or F | Fibers from the external band of baillarger originate in the ML.
T
343
T or F | some axons from the ML terminate in the non-specific nuclei of the CM.
T
344
Where do axons from gracilis terminate?
lateral VPL (lower body)
345
Where do axons from cuneatus terminate?
medial VPL (upper body)
346
Where do axons from trigeminothalamic tract terminate?
VPM (face)
347
What does area 3a detect?
muscle stretch
348
What does area 3b detect?
slow-adapting cutaneous receptors
349
what does area 2 detect?
joints/mm. fascia
350
What is a primary order neuron?
psudounipolar neuron of the DRG
351
The primary order neuron makes up the ______s.
DCs
352
What does the secondary neuron do?
Goes from DCNs to VPL makes up ML
353
What does tertiary order neuron do?
goes from VPL to neocortex
354
What does quaternary order neuron do?
it remains in neocortex (areas 3,2,1 and 43)
355
What does the anterolateral ascending spinal pathway carry?
pain, temp, and crude touch
356
Trace the pathway of anterolateral ascending spinal pathway from impulse to lateral spnothalamic tract.
psudounipolar cell sensation------>terminate in laminae 1-3 (primarily 2)----->most signals to lamina 5------->anterolateral movement across white commissure------->anterior lateral funiculus----->lateral spinothalamic tract
357
T or F The segment of entry in the anterolateral ascending spinal pathway is normally 3 to four segments above the beginning segment.
F | 1 to 2 segments above
358
T or F | In the lateral spinothalamic tract the lower body is medial and upper body is lateral.
F | vice versa
359
T or F | lateral spinothalamic tract crosses in the cord whereas the ML crosses in the brain.
T
360
T or F The spinoreticular, spinotectal, lat. spinal thalamic, spinal mesencephalic, and spinoolivary are all part of posterolateral ascending spinal pathway?.
F | anterolateral
361
T or F | The map systems of the ML and anterolateral ascending spinal pathway are reversed in orientation once at the thalamus.
F | indentical at thalamus
362
What is the procedure done when a patient is experiencing chronic severe pain?
anterolateral cordotomy
363
T or F | An anterolateral cordotomy will only last about 3 years.
T
364
What is the destination of the spinomesencephalic tract?
PAG this tract is considered spinoreticular
365
What is the sensation of the neospinalthalamic tract?
1st pain and crude touch 1st pain pathway is very well localized, well tolerated, and very rapid
366
What is the destination of the neospinalthalamic tract?
VPLc---->Areas 3,1,2 (SS1)
367
What does the paleospinothalamic tract carry?
2nd pain and temp pain is poorly localized and poorly tolerated "suffering pain"
368
What is the destination of the paleospinalthalamic tract?
post. nucleus of the thalamus---->retroinsular area of area 43----->anterior insula----->amygdala/entorhinal----->hippocampus
369
What kind of axons carry slow pain?
C
370
What kind of axons carry fast pain?
A delta
371
What tracts are involved in pain gating?
raphespinal
372
Trace the pain-gating pathway.
Anterolateral ascending spinal pathway----->PAG---(descending)----->Raphe magnus----->raphespinal trcats----->lamina 2
373
What do neurons leaving the PAG secrete?
enkephalins
374
Are enkephalins excitatory or inhibitory?
inhibitory
375
Neurons from raphe magnus terminate on lamina 2 and _____. These neurons secrete ______.
5 secrete serotonin
376
How does serotonin affect lamina 2?
excitatory
377
How does serotonin affect lamina 5?
inhibitory
378
What is the purpose of serotonin exciting lamina 2?
When lamina 2 is excited it will inhibit lamina 1,2,5 using endorphins.
379
T or F | Endorphins and Enkephalins are the body's natural painkillers.
T
380
Why does putting pressure on a wound relieve pain?
The Aa and Ab that ascend the spinal cord as cuneatus and gracilis give a branch to lamina 2. The pressure excites lamina 2 and releases endorphins. endorphins shut down pain
381
What is referred pain?
When class B fibers from the splachnic nn. bring in pain and temp from viscera. Lamina 5 cannot distinguish between B axons and C/Ad axons. so pain can be misinterpreted
382
What is the most lateral tract of the spinal cord?
spinocerebeller tract.
383
What sensation does the spinocerebellar tract carry?
discrimination touch, light louch, pressure, proprioception
384
Tract the spinocerebellar tract from origin of sensation to the inferior cerebellar pedunkle.
primary stretch receptor---->DRG----->medial lamina 7 (nucleus of clarke)------>posterior lateral funiculus----->posterior spinocerebellar tract----->inferior cerebellar pedunkle
385
Which is larger, posterior spinocerebellar tract, or ant.?
posterior
386
Nucleus of clarke goes from where to where?
C8-L3
387
What is the nucleus of clarke?
a relay for the spinocerrebellar tract.
388
After entering the inferior cerebellar pedunkle what happens to the spinocerebellar tract?
inferior cerebellar pedunkle---(now MOSSY FIBERS)-->cerebellar granule cells--(PARALLEL FIBERS)-->ends on purkinje cells (ipsilateral vermis and paravermis)
389
T or F | axons will ascend in fasiculus cuneatus below L3 until they reach a segment where a nucleus of clarke is present.
F | they ascend in fasiculus gracilis below L3
390
What happens above C8? (regarding spinocerebellar)
it will not descend to look for clarke. it ascends in cuneatus until reaching the accessory cuneate nucleus in the medulla
391
The axons leaving the accessory cuneate nucleus then do what?
enter the cerebellum through the inferior cerebellar pedunkle
392
What is the tract from the accessory cuneate nucleus to the cerebellum called?
cuneocerebellar tract
393
What tract creates the posterior external arcuate fibers?
cuneocerebellar tract
394
Where is the anterior spinocerebellar tract found?
coccygeal, sacral, and lumbar region (nothing above L1)
395
T or F | Anterior spinocerebellar tract axons have a synapse at the n. of clarke.
F | any neuron in lamina 7 except clarke
396
Do Anterior spinocerebellar tract axons go to the contralateral cerebellum?
Yes, 85-90% of the time
397
Where do axons from the Anterior spinocerebellar tract axons enter the cerebellum?
superior cerebellar pedunkle
398
parvermis aka
intermediate lobe