cardio di 1st test Flashcards
cardiac ischemia
2 pathophysiological causes
- decreased blood supply
2. increased metabolic
2 causes of decreased blood supply
- coronary spasm
2. coronary obstruction
causes of coronary spasm
- rupture of coronary plaque
- stress
- endocrine disorders
What causes coronary obstruction?
atherosclerotic plaques or thrombosis
systemic hypertension and hypertrophy are examples of
increased metabolic demand of cardiac muscles
A decreased blood supply =
decreased O2 and Glucose
drop in ATP
A decreased blood supply results in anaerobic respiration creating ______ which activates pain receptors
acidosis
3 steps of decreased blood supply and is the step reversible
- ischemia-reversible
- injury-reversible
- necrosis-irreversible
2 tests for injury and necrosis
- cardiac enzymes
2. ECG
What enzymes are tested for cardiac injury and necrosis?
CK-MB
tropinin 1
CK-MB doesnt change for the first _ hours
4
CK-MB spikes in the first __ hours and returns to normal by ______ hours
24
72
If CK-MB levels do not return to normal a ___________ results
reinfarction
How long does troponin 1 stay elevated after MI?
14 days
first notable rise in troponin 1 levels 3 hours after MI
What shows on an ECG representing cardiac ischemia?
an inverted T wave and/or depression of S-T segment
What shows on an ECG representing cardiac injury?
elevation of S-T segment (above P-Q segment)
What shows on an ECG representing cardiac necrosis (MI)?
abnormalities of Q-wave!!
ascending Q-wave is > 30% of R
chest pain from decreased blood supply is known as?
angina
Heart Failure definition
when the heart can not pump enough blood to systemic circulation (decreased cardiac output
Top five reasons for Heart Failure in US?
- MI
- systemic HTN
- myocarditis
- stenosis of cardiac valves
- regurgitation
Left Sided heart failure has what target organs?
- kidneys
- heart
- brain
Decreased renal blood flow due to LSHF causes what?
- decreased GFR
- increased Angio 2 and aldosterone
- increased NA/H2O
- increased blood pressure
- hepato/splenomegaly
- increased CHP=peripheral edema
- Jugular Venous Distension
LSHF causes what to the heart?
decreased blood flow
ANGINA
LSHF to the brain causes what?
weakness, fatigue, mental confusion
Backup of blood from the left ventricle will cause what?
pulmonary edema
- dyspnea
- tachypnea
- COUGHING WITH SPUTUM PRODUCTION
Increased PCO2 causes
acidosis (pain) (dyspnea) (tachypnea)
Right Sided heart failure (RSHF) causes what to happen directly? (forward)
decreased blood supply to the lungs
- tachypnea
- dyspnea
- central cyanosis
Does RSHF cause increased PCO2?
yes, acidosis
Does RSHF cause pulmonary edema?
NO
Positive hepatojugular reflex happens from both sides of heart failure, but is mainly associated with which side?
Right
Subjective findings in LSHF?
- weakness/fatigue
- memory loss/confusion
- breathlessness/cough/insomnia
- anorexia/palpitations/diaphoresis
Subjective findings in RSHF?
- weight gain/gastric distress
- transient ankle swelling
- abdominal distension
- anorexia/ nausea
Objective findings RSHF?
- edema/ascites
- left parasternal lift
- increased jugular BP/ vein pulsations
- positive hepatojugular reflex
Objective LSHF findings?
- Tachycardia/ moist rales
- decreased S1, S2, S3
- pleural effusion
- pulsus alternans/diaphoresis
5 conditions causing heart failure
- Abnormal volume load
- Abnormal pressure load
- Myocardial dysfunction
- filling disorders
- increased metabolic demand
Abnormal volume load causes
- aortic/mitral/tricuspid incompetence
- overtransfusion
- left-to-right shunts
- secondary hypervolemia
Abnormal pressure load causes
- aortic stenosis
- idiopathic hypertrophic subaortic stenosis
- coarctation of the aorta?HTN
Myocardial dysfunction causes
- cardiomyopathy
- CAD/ ishemic infarction
- Dysrythmias/presbycardia
- toxic disorders
Filling disorders causes
- mitral/tricuspid stenosis
- cardiac tamponade
- restrictive pericarditis
Increased metabolic demand causes
- anemias/fever
- thyrotoxicosis/beriberi
- Paget’s/ arteriovenous fistula
Stage 1 HTN
140-159/90-99
Stage 2 HTN
160-179/100-109
Stage 3 HTN
180-199/110-119
Stage 4 HTN
greater than 200/ greater than 120
complications of systemic HTN
- MI
- Renal failure
- CVA
- Retinal damage
145/105 represents what stage HTN?
Stage 2 because diastolic is 105 in stage two even though 145 is stage one systolic
take the largest number and label what stage it is
P-wave represents
atrial depolarization
QRS segment represents
ventricular depolarization
Qrs segment length normally
.08-.12 sec
T-wave represents
ventricular repolarization
P-Q (P-R) segment length normally
.12-.2 sec
P-Q (P-R) represents
how fast electricity travels from SA node to muscles
Q-T interval normal length
.36-.44
HR=60-10 BPM
Q-T interval represents
contraction to relaxation
Equation for calculating HR
HR=60/R1-R2 (sec)