Nervous system Flashcards
What is the nervous system?
transports messages
controls body
Nervous syestem has two major branches
central and peripheral
Central nervous is composed of?
brain and spinal cord
PNS or peripheral nervous system is composed of?
any kind of nerves coming off of the brain and spinal cord
Where are the cranial nerves and are a part of what nervous system
inferior side of the brain, peripheral
PNS can be broken down into
somatic and autonomic
Somatic has to do with
skeletal muscles and any kind of motor function
Somatic is not always what….
voluntary skeletal muscle contractions. Sometimes involuntary.
Examples of involuntary skeletal muscle
posture,
Examples of involuntary skeletal muscle and are part of what branch of nerves?
posture, reflexes…. part of somatic
What branch of nerves are cardiac muscles and smooth muscles a part of?
autonomic
Autonomic can be broken down into what two branches
parasympathetic and sympathetic
parasympathetic consists of
rest
sex
digest
Why are parasympathetic and sympathetic a part of the autonomic nerve system
to help build in some sort of control
sympathetic
fight
flight
freeze
when parasympathetic is turned on sympathetic is turned
off
when sympathetic is turned on parasympathetic is turned
off
efferent
messages being sent away from the brain
afferent
messages being sent toward the brain
when we are in flight or fight (sympathetic) our heart is and blood pressure is
beating fast and elevated.
caffeine and nicotine causes what to turn on
our sympathetic side
Insomnia, inability to be turned on is because you need to turn of what and on what nervous system
sympathetic and turn on parasympathetic
How do you turn flight or fight off?
relaxation, meditation, stop stressing about things that dont matter. Learn to let go of everything, be numb towards everything pos, and neutral.
neurophysiology
Nerve to nerve or neuron to neuron
-70 milivolts
cell at rest
The Nervous System is the
rapid control system of the body
There are two anatomical divisions to the Nervous System:
The Central Nervous System (CNS)
The Peripheral Nervous System (PNS)
They work together as a single coordinated whole
The Functions of the Nervous System
sensory input
intergration
motor output
integration
process stimuli
interpret stimuli
Organization of the Central Nervous System
the Brain and Spinal Cord
Brain and Spinal Cord CNS does what for information and emotions
process & integrate information, store information, determine emotions
Brain and Spinal Cord CNS does what for muscle
initiate commands for muscle contraction, glandular secretion and hormone release (regulate and maintain homeostasis)
Brain and Spinal Cord CNS are connected to
all other parts of the body by the Peripheral Nervous System (PNS)
Anatomical connections of the PNS
spinal nerves are connected to the spinal cord
cranial nerves are connected to the brain
two functional subdivisions of PNS
sensory (afferent) division
motor (efferent) division
sensory (afferent) division
somatic afferents - skin, skeletal muscle, tendons, joints
special sensory afferents
visceral afferents - visceral organs
motor (efferent) division
motor (efferent) neurons
muscles/glands
based on our sensory input we always retrieve from… and where
memory and the frontal lobe
when picking up a glass where is your sensory input sending information to and what?
your motor output and what muscles need to contract used to pick up the glass
motor output is always what pathway
effector
visceral organs
internal organs
unresponsiveness is what
a necessary life function1
The brain and spinal nervous system is set aside to
process
intergate
store
and retrieve later
1st 5 years of development are so crucial for our nerves because its when
our axons develop myelin around them and makes them work/send impulses
glands are what in the nervous system
PNS motor efferent division
body temp sweat gland is what
eccrine
sebaceous is
oil gland
apocrine
body odor
Somatic Nervous System (SNS)
voluntary motor neurons
output to skeletal muscles
Autonomic Nervous System (ANS)
involuntary visceral motor neurons
output to smooth muscle, cardiac muscles and to glands
two cooperative components:
Autonomic Nervous System (ANS)
two cooperative components:
sympathetic division
parasympathetic division
Sympathetic Division – for muscular… and?
exertion and for “fight or flight” emergencies
Parasympathetic Division – for
metabolic/ physiologic “business as usual” (“feed or breed”)
Nerve cell physiology is primarily a
cell membrane phenomenon
Information transmission differs between what parts of the nerve?
dendrites and axons
Neuron Processes is done in the?
axons and dendrites
dendrites are
short, tapering, highly branched extensions of the soma
contain some cell organelles
receptive—initiate and transmit graded potentials (not action potentials) to the cell body
Are dendrites mylinated
no
axons
A single process that transmits action potentials from the soma
axons originates from
a cone-shaped “axon hillock”
axon length
May be long (1 meter) or short (<1 mm)
long axons called
nerve fibers
axons have up to how many terminal branches
10,000
each terminal branch has a _____ that?
an axon terminal that synapses (joins) with a neuron or an effector (muscle or gland cell)
Axoplasm:
the cytoplasm of the axon
Axolemma defined
the cell membrane of the axon, specialized to initiate and conduct action potentials (nerve impulses)
Axolemma do what
initiated at the axon hillock (trigger zone), travels to the axon terminal
causes release of neurotransmitter from terminal
neurotransmitters can excite or inhibit
transfers a control message to other neurons or effector cells
Myelin Sheath
lipid-rich, segmented covering on axons
most larger, longer axons are
myelinated
dendrites are never
myelinated
myelin protects & electrically insulates
the axon
myelin increases?
the speed of nerve impulses
myelinated fibers conduct impulses
conduct impulses 10-150x faster than unmyelinated fibers
150 m/sec vs. 1 m/sec
impulses are sent in what order
from the dendrites through the body (soma) through the axon, down the axon terminal branches to the synapse.
Myelinating Cells
neurolemmocytes (Schwann cells) in the Peripheral NS
oligodendrocytes in the Central NS
Myelination occurs during?
fetal development and the first year of life
each myelinating cell wraps around a… how many times and does what?
axon up to 100 times, squeezing its cytoplasm and organelles to the periphery
cell body is also known as
soma
myelin sheath:
multiple layers of the cell membrane
neurolemma (sheath of Schwann):
outer layer containing the bulk of the cytoplasm and cell organelles
Myelinated Fibers
Myelin sheath neurofibril nodes (Nodes of Ranvier)
neurofibril nodes (Nodes of Ranvier)
periodic gaps in the myelin sheath between the neurolemmocytes
depending on the neurotransmitters they can do what at the synapse
turn one nerve off and the other on
depending on how strong or weak the signal from the first neuron is, is going to depend on if
the message is going to continue onwards
Unmyelinated Fibers
surrounded by neurolemmocytes but no myelin sheath present
Presynaptic neuron
before the synapse. sending the initial message
postsynaptic neuron
after the synapse. neurotransmitter has already gone to the next one and tell us the effect of that impulse
neurolemmocytes may enclose up to____axons (unmyelinated fibers)
15
Different types of receptors in nerves for what
for different processes to occur
dendrites are where the impulses
start
neurolemmocytes guide
regrowth of neuron processes after injury
The receptive portion of a nerve
dendrites
Gray matter
unmyelinated cell bodies & processes
White matter
myelinated processes in various fiber tracts
Classification of Neurons
Structural:
Funvctional
Structural classification of neurons
based on the number of processes extending from the cell body
Functional classification of neurons
based on the direction (location) of nerve impulses
Afferent =
Sensory Neurons
afferent = towards
CNS
nerve impulses from specific sensory receptors (touch, sight, etc.) are transmitted to
the spinal cord or brain (CNS)
afferent neuron cell bodies are located
outside the CNS in ganglia
efferent are
away from CNS
Efferent =
Motor Neurons
nerve impulses from CNS (brain and spinal cord) are transmitted to
effectors (muscles, endocrine and exocrine glands)
efferent neuron cell bodies are located inside the
cns
signal itself is always physically on what
axon
Cell membrane of an axon
axolemma
Where does the action potential (nerve impules) happen in the axon
axolemma
Where are neurotransmitters released
the axon terminal
neurotransmitters besides aceytocholine
dopamine
Dopamine excites or inhibits?
excites
Insulation around the axon
myelin
Myelin is made of
lipids… fat cushioning
exposed area on axon where there isn’t myelin is the only area that impulse will
jump to blank spots on the nerve fiber
bubble of myeline is known as as
neurolemmocyte– schwann cell
What makes myelin
supporting cells in the nervous system called oligodendrocytes
oligodendrocytes have the ability to
cap on to the axon, spin it and created this cushion around it.
schwann cells are
myelin
membrane around the axon
myelin
two types of fibers of axons
myelinated and unmyelinated
which is faster, myelinated or unmyelinated?
myelinated
why would you want a nerve to be myelinated
causes you to have a faster response
all of our ___ and ____ should be myelinated?
sensory input and motor output
What nerves should not be myelinated or it does not matter as much?
integration- CNS
Association Neurons carry
nerve impulses from one neuron to another
Lumin on axon tells us
that there is a membrane- myelinated sheath
Association Neurons =
(= Interneurons)
99% of the neurons in the body are
interneurons
most interneurons are located in the
CNS
voltage
the measure of potential energy generated by separated charges
CNS will be unmyelinated why?
to give it time to figure out what it is
CNS being unmyelinated and myelinated gives us what?
our two types of tissues seen here. Aka white and gray mater
voltage is alway measured between
two points – the inside versus the outside of the cell
voltage is referred to as a potential since
the charges (ions) are separated there is a potential for the charges (ions) to move along the charge gradient
You’ll see a lot more gray matter where and why
the CNS, because thats where processing and integration happen. Don’t need it to happen to fast
white matter is going to be the tracts
that send and receive information from everywhere else
why does the percentage of white matter to gray matter change from the brain to the spine?
because not as many peripheral nerves are coming off the brain as the spinal cord
functional classification is based on
where nerves are going efferent or afferent and are they sensory or motor
afferent is your
sensory
Afferent, sensory pathways are always going to go to the
dorsal root (ganglion) and then the posterior horn
Ganglia has
a bunch or bundle of nerve cells
Integration happens with an
interneuron
afferent to ____ to _____
integration
efferent
current neurophysiology
the flow of electrical charge from one point to another
in the body, current is due to the movement of charged ions
resistance neurophysiology
the prevention of the movement of charges (ions)
caused by the structures (membranes) through which the charges (ions) have to flow
Cell interior and exterior have different chemical compositions
- Na+/K+ ATPase pumps change the ion concentrations
- a semi-permeable membrane allows for separation of ions
Ions attempt to reach electrochemical equilibrium
two forces power the movement of ions.
- individual ion concentrations (chemical gradients)
- net electrical charge (overall charge gradient)
the balance between concentration (chemical) gradients and the electrical gradient known as the
electrochemical equilibrium
the external voltage required to balance the concentration gradient is the
equilibrium (voltage) potential
Membrane Ion Channels regulate
ion movements across cell membrane
Membrane Ion Channels are specific for
a particular ion or ions
many different types
of membrane ions channels
may be passive (leaky)
may be active (gated)
active (gated) membrane ions channels
- gate status is controlled
- gated channels are regulated by signal chemicals or by other changes in the membrane potential (voltage potential)
Resting Membrane Potential (RMP)
electrical charge gradient associated with outer cell membrane
Resting Membrane Potential (RMP) is present in
all living cells
the cytoplasm within the cell membrane is _____ charged due to the
negatively, due to the charge disequilibrium concentrations of cations and anions on either side of the membrane
RMP varies from about
-40 to -90 millivolts (a net negative charge inside relative to a net positive charge outside the cell)
Resting Membrane Potential is similar to a battery
stores an electrical charge and can release the charge
2 main reasons for Resting Membrane Potential stores and releases an electrical charge this:
- ion concentrations on either side of the plasma membrane are due to the action of the Na+/K+ ATPase pumps
- plasma membrane has limited permeability to Na+ and K+ ions
polarized membrane
-primarily, Na+ and Cl- are outside making the membrane
plasma membrane has what typically inside and what typically outside
K+, Cl-, proteins- and organic phosphates- are inside
Na+ and Cl- are outside
plasma membrane has limited permeability to
Na+ and K+ ions
Resting conditions of a membrane are
Na+/K+ ATPase pumps 3 Na+ ions out and 2 K+ ions in per ATP hydrolysis – opposing their concentration gradients
concentration gradient drives Na+ to
go into the cell
concentration gradient drives K+ to go
out of the cell
if the cell membrane were permeable to Na+ and K+ ions, then
Na+ and K+ ions would diffuse along their electrical and chemical gradients and would reach equilibrium
if the cell was at equilibrium in terms of ion concentrations and charge, their would be
no potential energy available for impulse transmission
Neuron Membrane at rest is polarized causing the cytoplasm inside to be relative to the
negatively charged relative to the outside
Neuron Membrane at rest is polarized
and the net negative charge in the cytoplasm attracts
all cations to the inside
Association neuron- interneuron does what
interprets message sent to it and passes the baton
association neuron stays where
inside the gray matter
efferent pathway starts from
your anterior horn through the ventral nerve root (no bump) exits spinal level becomes a longer motor nerve and synapses right at the muscle
When the cytoplasm has a net negative charge and attracts cations inside what leaks in despite membrane permeability
Na+
what keeps working to pump 3 Na+ ions out and 2 K+ ions in
Na+-K+ ATPase, opposing the two concentration gradients (for Na+ and K+)
the resting potential
the electrochemical gradient at rest