Chapter 3 Bio Flashcards
Nucleus
The brains of the cell
Mitochondria
Make energy out of food
Ribosomes
Make protein
Rough endoplasmic reticulum
Transport and storage
Smooth Endoplasmic reticulum
Creates lipids or fats
Chloroplast
Creates glucose
Three basic steps to enzyme actions and regulation
1) amino acids bind at active site to form enzyme
2) cause internal bond rearrangements-leading to catalyst
3) release the products and repeat
Regulatory controls for enzyme action
Substrate specific
Feedback controls
Nucleic acids types
DNA
RNA
Made of nucleotide monomers
RNA
DNA
3 parts to a nucleotide
Nitrogenous bases
Pentose sugar
Phosphate group
Pentose sugar DNA
Dexyribose
Pentose sugar rna
Ribose
Nitrogenous bases DNA
Adenine
Cytosine
Guanine
Thymine
Nitrogenous bases rna
Adenine
Cytosine
Guanine
Uracil
Nucleic acids are organic or inorganic
Organic
DNA looks like
Double helix
Nucleic acid is different from organic compounds because
Has 5 carbon sugar instead of six carbon
A pairs up with
C pairs up with
DNA
T
G
A pairs up with
C pair up with
RNA
U
G
Genetic material
DNA
Carries hereditary inform from nuclear DNA to the cytoplasm
Inside cell
RNA
Deoxyribose sugar
Phosphate
Hydrogen bond
Sugar/phosphate backbone
Hydrogen bonds together a…t or c…g
What has complimentary bases
DNA strands
Where does energy come from in ATP or ADP bonds
Phosphate
It’s what’s released
Mass number
Protons + neutrons
All isotopes of an element have
Same number of protons
Same chemical characteristics
Unstable isotopes that decay
Radioactive isotope
Have a different number of neutrons
Same number of protons
Same chemical characteristics
Isotopes
The first three shells hold how many electrons
2,
8,
18
Fundamental structure and functional unit of living organism is
Cell
Cell actions are made possible by subcellular structures
Principle of complementary
Cells come from
Cells
Plasma membrane
Outer boundary
Acts as semipermeable barrier
Cytoplasm
Intracellular fluid packed with organelles
Nucleus
Brain of cell
Controls it
Stores DNA
Cell secretions
Aid in digestion
Some act as lubricants
Cholesterol in a membrane
Stabilizes and decreases fluidity of membrane and phospholipids
Polar and nonpolar regions
Transmember proteins or integral proteins
Transport
Form channels/pores
Small water soluble molecules or ions move through these pores
Transmembrane proteins or integral
What proteins are enzymes
Transmember
Or peripheral
What proteins can be receptors for hormones or messengers
Transmember
Signal transduction
Integral proteins relating messages to the cell interior
Peripheral proteins
Attached loosely to integral proteins and easily removable
Proteins that help join cells together
Peripheral
Proteins that help motor, mechanical function and muscle cell contractions
Peripheral
Smallest unit of matter
An atom
Glycocalyx
Sugar covering
Tight junctions
Impermeable junctions
Form continuous seals
Desmosomes
Anchoring junctions
Velcro
Internal network of fiber
Gap junctions
Communicating junctions
Ions and small particles to pass
The diffusion of a solvent such as water through a selectively permeable membrane
Osmosis
Carrier mediated facilitated diffusion
Protein carrier specific for one chemical
Normally lipid insoluble solutes
Causes transport protein to change shapes
Channel mediated facilitated diffusion
Through a Chanel protein
Mostly ions
Cells retain normal size and shape in what solution
Isotonic
Cells loose water by osmosis in what solution
Higher concentration outside of cell
Hypertonic
Cells take on water by osmosis until they become bloated in what solution?
Lower concentration of solutes outside the cell
Hypotonic
Cytosol
The viscous semitransparent fluid in which other cytoplasmic elements are suspended
Mitochondria
Jelly bean
Power plants of cell
Provide most of its atp
Ribosomes
Specs in cell composed of proteins and a variety of RNAS call ribosomal rnas.
Sites or protein synthesis
Can be floating freely of membrane bound
Rough endoplasmic reticulum
It’s Ribosomes manufacture protein.
Secretory cells, antibody immune cells, liver cells
Enzymes active sites on here
Membrane factory
Smooth ER
Enzymes metabolize, synthesis hormones and fats.
Absorb fats.
Detoxify drugs.
Break down glycogen
Golgi apparatus
Traffic director for cellular proteins. Or post office… packages and delivers
Peroxisomes
Small sacs containing a variety of powerful enzymes
Oxidase and catalases
Lysosomes
Contain activated digestive enzymes Rids bacteria and cell debris Eats cells Digests particles Metabolic-breaksdown
Microtubules
Structure
Supports cell and gives it shape
Bug yellow
Intermediate filaments
Protein fibers
The stable cytoskeletal elements: resists mechanical forces acting on the cell.
Microfilaments
Muscle contractions
Fine filament
Lil blue
Centrioles
Flower looking tubes
9 microtubules
Forms spindles during mitosis
Microvilli
Tubular extension of plasma membrane increase surface area for absorption
Nuclear envelope
Seperates plasms and regulates passage of substances to nucleus
Nucleolus
Ribosomes subunit manufacture
Chromatin
DNA
Fluid mosaic model
Moving mix of lipids proteins and carbohydrates
What determines membrane function
The kinds and numbers of membrane molecules, especially proteins.
Glycocalyx is made up of
Carbohydrates
Lipids
Proteins
Weight ratio of membrane structure
50/50
Lipid/protein
Proteins
Hydrophilic or phobic
Philic
Anything on inside of the plasma membrane is hydro….
Phobic
does cholesterol in the plasma membrane increase or decrease fluidity of phospholipids
Increases
Lipids that contribute to glycocalyx
Glycolipids
Integral proteins
Located in membrane Channels- has a receptor(lock) Transporters Receptors Intracellular junctions Enzymes Anchor Cell recognition
Permeability depends on
Molecular size
Lipid solubility
Charge- zero charge allowed
Presence of channels and transports
Passive transport
Diffusion
Ball pit
Balls falling out from the ceiling
No cellular energy expended
Examples of passive transport
Simple diffusion
Diffusion across a cell membrane
Facilitated diffusion
Higher concentration to Lower
Active transport
Opposite of diffusion
Uses atp
Shoving balls back into ceiling
Low concentration to higher
Against the concentration gradient
Does diffusion require atp
No
Simple diffusion
Selective
Water and lipid soluble molecules move freely
Factors affecting diffusion
Increased temp increase Greater concentration increases Larger surface area increases Smaller particles increase Time- diffusion decreases over time
Diffusion of water from an higher area of concentration to a lower area
Osmosis
What molecules move through aquaporin channels or wiggle through phospholipids
Polar water molecules
How to find water concentration
1/solute concentration
Cell shrinks due to more solute in a solution than in a cell
Hypertonic
A cell swells due to lower solute inside the cell than in the solution
Hypotonic
Total concentration of all solute particles
Same as concentration
Osmolarity
Osmotic pressure
Pulling pressure
Net pressure effect of individual particles in solution
cells shrink due to lack of water what pressure is increased
Osmotic
Cell wants to pull in water
Hydrostatic pressure
Constant
Whole solutions pressure
Blood pressure is what kind of pressure
Hydrostatic
Whole solution or organism
The ability of a solution to change shape of cells by altering their internal water volume
Tonicity
Solute concentration is the same inside and outside the cell
Isotonic solutions
Normal saline solution is what to blood plasma
Isotonic
Always describing what in tonicity
The solution
What is the only thing moving in tonicity
Water in or out of the cell
A lot of salt or ions in a solution it is
A hypertonic solution
Increased solute
Decreased h2o
Hypertonic
Water moving out of cell and shrinks
Cells shrinking
Cremation
Cell has more solute in it then the solution does what happens?
Hypotonic solution
So the cell swells up when water moves into the cell to equalize it with the solution
More water on the outside of the cell cause
More water to move into the cell- hypotonic
Mess water on the outside of the cell causes
Less water on the inside of the cell
Hypertonic
Hypertonic
Water moving out
Cell shrinks
Active transport processes
Some substances are too big
Have wrong charge
Move against concentration gradient (lower to higher)
Energy is needed
Active transport has two mechanisms
Active transport (primary/secondary) Vesicular transport (vesicul)
Na+/K+ pump facilitates
Is how cells communicate and neurons send messages
Points to remember about na+/k+ pump
1) A cell at rest is negative on the inside.
2) The reason it is negative on the inside due to amount of K. Circle K.
3) Once this charge flips due to sodium coming in. This creates a spark. (Action potential). Known as depolarization.
4) repolarization or back to rest. K+
Depolarization is because of Na+ what is repolarization.
Because of K+. And wanting to go back to rest
Why is Na+/k+ called a pump
Because it’s actively pumping the opposite ion to the opposite region
every time creating a spark-atp is hydrolyzed
What allows batteries to work
Na+/k+ pump
Without what energy will the pump not work
ATP
Ratio for pump
Always pumping out 3 sodium for every 2 potassium in
What cause potassium to be negative in the pump
The weight of 3 sodium and 2 potassium
What creates spark in Na+/k+ pump, known as
As we increase potassium k+ in and decrease the sodium Na+
Depolarization
Electrochemical gradient
Net effect of all charged ions on either side of membrane
In Na+/k+
All cells are polarized
Negative inside
2K+
Positive outside
3Na+
ATP energy is used how to move substances in active transport
Indirectly
How does atp move substances in active transport
ATP energy drives an ion pump. Creating a concentration gradient.
The a carrier protein uses the energy to transport another substance.
Exocytosis
Cell vacuole release contents
Endocytosis
Taking of matter from the exterior of the membrane to form a vacuole
Cams or cellular adhesion molecules
Anchors
Arms
Form junctions or desmosome
Stick into blood vessels
Cilia
Tubes on the outside of a cell long fibers are called microtubules
Move liquid pass surface of cell
Flagella
Have a tail and head
Used for locomotion
Cytoskeleton is made up of
Microfilament
Intermediate filament
Microtubules
Forms frame work for organelles and cell shape
Microfilaments
Changes in cell shape
Muscle contractions
Cell division
Intermediate filaments
Anchor
Formation of nucleus
Microtubules
Cilia/flagella motility
Chromosome movement
Organelle movement
DNA is packaged how in chromatin
Supercoiling
Grainy threadlike material
Chromatin
Form nucleosome core
Histone proteins
DNA wrapped around nucleosome forms
Chromatin fibers
G1
Growth and metabolism
Protein replication
S
Synthesis of DNA
prep for division
DNA replication
G2
Metabolism
Prep
Enzyme proteins for mitosis
M phase
Nuclear division Prophase Metaphase Anaphase telophase Cytokinesis
Helicase
Unwinds DNA
DNA polymerase
One strand is the template Builds complimentary strand Bonded with hydrogen A-T C-G
Protein synthesis
1) DNA serves as templet and is transcripted into pre-MRNA
2) RNA Processes pre-mRNA to (messenger)RNA
3) mRNA leaves nuclear envelope to go to cytoplasm and is translated in ribosome
4) mRNA is read to build protein structure
Na+/K+ ATPase
Pump
And enzyme for atp
How many Na+ out and K+ in
3Na+ out
2K+ in
IPMAT
Interphase Prophase Metaphase Anaphase Telephase Cytokinesis-splitting on cytoplasm
Replication
Unzipping DNA and create another strand from the first template DNA
Opposite of one strand
Genetic Condon matches with
Anticodon
AUG
Anticodon?
TAC
Building protein
Protein synthesis
DNA ATG transcribed into UAC MRNA
mRNA leaves the nucleus into the cytoplasm and goes to the ribosome.
Ribosome only makes proteins
MRNA gives message to TRNA to translate it and links the anticodons to an amino acids. To make a protein.
Going to protein via mRNA and tRNA would be
translation
Replication DNA unzipping itself and copying itself happens in
Mitosis
Transcription vs translation
Protein synthesis
Transcription
DNA to mRNA
Translation
mRNA to protein
Happens at ribosome
And with tRNA
TAC
AUG
mRNA doesn’t go straight to the protein what is invoked
Translation
in translation what steps occur after TAC
AUG the
UAC
Then the amino acid
Gene expression
DNA contains a sequence of nitrogenous bases which codes for the sequence of amino acids in a protein
Each codon is composed of… to form?
3 bases to form genetic code
MRNA has what kind of base series in DNA
Complimentary
tRNA carries
Particular amino acid and 3 base anticodon complimentary to codon of mRNA
What bonds form proteins
Peptide