Chapter 5 Bio Flashcards
The skin is composed of what kind of tissue.
epithelial and connective tissue working together for specific purpose
Largest organ in body
Skins
Physiology of skin
Regulate temp Protection Sensation Communication Excretion Immunity Blood reservoir Synthesis for vitamin d
How does skin regulate body temp
Insulates and radiates
How does skin protect the body
Physical barrier and conserves water
Sensation and the skin
Has varied sensory nerve endings
How does skin communicate
To other humans by signals and expressions and touch
How doe the skin excrete
In sweat (h2o, salts, small organic compounds)
How does skin help with immunity
Phagocytes in the epidermis are important for the immune system for defense
Phagocytes
Type of cell in the body capable of engulfing and absorbing bacteria
How does the skin affect blood
It is a major reservoir for it
Why does the skin synthesis vitamin d
To absorb calcium
What is the architecture of the skin
Epidermis
Dermis
Hypodermis
Epidermis
Epithelium
Dermis
Areolar and dense irregular fibrous connective tissue
Areolar connective tissue
Loose irregularly arranged connective tissue. Consists of collagenous and elastic fibers
Hypodermis
Beneath the dermis
The subcutaneous layer next to, adipose layer, muscle or bone.
Adipose tissue
Fat
What is a stratified squamous epithelium
The epidermis
4 cell types found in the epidermis
Keratinocytes
Melanocytes
Langerhans cells
Merkel cells
Keratinocytes in the epidermis
90%
Filled with keratin (protein)
Waterproof barrier
Melanocytes in the epidermis
8%
Produce melanin
Pass melanin to keratinocytes
Langerhans cells in the epidermis
Phagocytes
Easily damaged by in light
Merkel cells in the epidermis
In the deepest layer of hairless skin
sensory transduction- touch
Epidermis cell layers
Stratum basale Stratum spinosum Stratum granulosum Stratum lucidum Stratum corneum
Stratum basale
Base
Single layer of cubiodal/columnar cells.
Holds stem cells, melanocytes and merkel cells.
Stem cells to keratinocytes, mitosis pushes the other layers to the top.
Stratum spinosum
On top of basale layer
8-10 layers of closely packed cells.
Where cell junctions and spot desmosomes are.
Made up of langerhans cells.
Stratum granulosum
2nd layer from the surface
3-5 layers of flattened with keratohyaline granules.
Beginning break down of nucleus, cell death initiated.
Stratum lucidum
Not always found, only in thick skin (palms, feet). 3-5 layers of clear flat dead cells with keratin.
Stratum cornermen
Top layer of epithelial cell layers
20-30 layers of flattened dead keratin filled cells
Continuously shed and replaced.
How long does it take for each cell to form and move from the stratum basale to the surface
2-4 weeks
What is the papillary region or layer?
Outer layer of the Dermis structure
Areolar is
Makes up the connective tissues and elastic fibers of the dermis structure
Dermal papillae
Is the mound like projections in the dermis structure that increases the surface area for nutrition from capillaries
Capillaries
Any fine branching blood vessel.
Or
A tube that has and internal diameter of hairlike thickness
Some papillae contain
Meissners corpuscles, are for light touch.
Reticular region makes up how much of the dermis
80%
The reticular region of the dermis is
Dense, irregular connective tissue.
Contains collagen, elastic fibers in a network surrounding various cells.
What do the fibers in the reticular region of the dermis do?
Give strength, elasticity, and extensibility.
What are tears in the reticular region of the dermis?
Stretch marks- long red or white streaks
Skin pigments
Melanin
Carotene
Hemoglobin
Melanin color is from
Yellow to black
What is melanin made by
Melanocytes
Where is melanin common
In mucous membranes, penis, nipples, areolas, face, extremities
What are the similarities and differences of melanocytes in all races
Similar in all races but the amount and type of melanin produced and distributed to the keratinocytes varies
What are freckles and lover spots
Melanocyte clusters
What is melanin synthesized from
Tyrosine (amino acid)
What does if radiation do to melanin
Increase enzyme activity (negative feedback)
Melanin production protects the body against?
UV radiation
Come Let us Get Sun Burned
Epidermal cell layers Corneum LUcidum Granulosum Spinosum Basale
Melanin ends in an IN so you know it’s a
Protein
Melanin is secreted by
melanocytes
Melanocytes is found where
In the dermis and the stratum basale
Why are melanocytes activated, migrate through the layers of the dermis and secrete melanin
UV light
What determines how many melanocytes you have and how much Melanie and you produce
Race, ancestry, background, individually
What areas are darker on individuals
Genitals
Elbows
Gums
Freckles
freckles are concentrated areas of? So there are a lot of what in that region?
Melanin and melanocytes
Melanin is made from
Amino acid called tyrosine
In order for Melanin to show up we need
UV radiation and tyrosine
The more melanin you have the more it’s protecting you from
UV radiation
Absence of melanin
Albinism and vitiligo
Albinism
The inability to produce or activate melanin
Why does albinism happening
Because they don’t have the ability to produce tyrosine
Albinism happens and is what kind of trait
At birth
Recessive trait
What color are albinos eyes
Pink
What is I colored hair color related to
Melanin because it give the pigment
Vitiligo is what type of condition
Autoimmune
Autoimmune is?
When the body attacks healthy cells
Vitiligo happens when
Melanin is decreased and the melanocytes are attacked