Nervous System Flashcards
Basic functions of nervous system
- Sensation
- Integration
- Reaction
Monitors changes/events occurring in and outside the body
Sensation
The parallel processing and interpretation of sensory information to determine the appropriate response
Integration
The motor ouput of the nervous system
Reaction
Changes are known as
Stimuli
cells that monitor changes
receptors
The activation of muscles or glands
Motor output
Similarities of Nervous and Endocrine system
Both monitor stimuli and react as to maintain homeostasis
Differences between NS and ES
- NS is rapid, and fast acting
- ES is slower and action are longer lasting
are blood-borne chemical signals
Hormones
2 Big initial divisions of NS
- Peripheral NS
- Central NS
The nervous system outside of the brain and spinal cord
Peripheral NS
- The brain + the spinal cord
- The center of integration and control
Central NS
3 kinds of neurons that connect CNS to the body
– sensory
– motor
– interneurons
CNS to muscles and organs
Motor neurons
sensory receptors to CNS
Sensory neurons
Connections Within CNS
Interneurons
Divisions of Peripheral NS
Sensory division
Motor division
it is the Afferent division
Sensory division
It is the Efferent division
Motor division
–Conducts impulses from receptors to the CNS
–Informs the CNS of the state of the body (interior and exterior)
Afferent division
–Conducts impulses from CNS to effectors (muscles/glands)
–Motor nerve fibers
Efferent division
Divisions of Sensory division
Somatic sensory
Visceral Sensory
Divisions of Motor Division
Somatic (Skeletal) NS
Autonomic NS
- VOLUNTARY (generally)
- Somatic nerve fibers that conduct impulses from the CNS to skeletal muscles
Somatic (or skeletal) NS
- INVOLUNTARY (generally)
- Conducts impulses from the CNS to smooth muscle, cardiac muscle, and glands.
Autonomic NS
Divisions of Autonomic NS
Sympathetic NS
Parasympathetic NS
The Autonomic NS division for “Fight or Flight”
Sympathetic NS
The autonomic division for “rest and digest”
Parasympathetic NS
Involuntary movment that controlled by Automic NS
– heartbeat
– blood pressure
– respiration
– perspiration
– Digestion
2 cell types of Nervous tissue
- Neurons
- Neuroglia
Functional, signal conducting cells
Neurons
Supporting cells
Neuroglia
Receive stimuli and
transmit action potentials
Neurons or nerve cells
organization of Neurons
Cell body (Soma)
Dendrites: Input
Axons: Output
4 types of Neuroglia found in CNS
- Astrocytes
- Oligodendrocytes
- Ependymal cells
- Microglia
- Star-shaped, abundant, and versatile
- Guide the migration of developing neurons
- Involved in the formation of the blood brain barrier
- Function in nutrient transfer
Astrocytes
Produce the myelin sheath which provides the electrical insulation for certain neurons in the CNS
Oligodendrocytes
- Line brain ventricles and spinal cord central canal
- Help form choroid plexuses that secrete CSF
Ependymal cells
Specialized macrophages
Microglia
2 types of Glial in PNS
- Satellite cells
- Schwann cells
- Surround clusters of neuronal cell bodies in the PNS
- Unknown function
Satellite cells
- Form myelin sheaths around the larger nerve fibers in the PNS.
- Vital to neuronal regeneration
Schwann cells
When a cell is exposed to chemical signal for a prolonged period, it tends to lose ability to respond with its original intensity
Drug addiction
What does drug addiction do to receptor proteins?
They are exposed to high levels for neurotransmitter molecules for high periods of time
How does nerve cell response to prolonged period exposure of receptor proteins from neurotransmitters?
They respond by inserting fewer receptor proteins into the membrane
Neuromodulator that causes large amounts of neurotransmitters to remain in synapses for long periods of time
Cocaine
- is made of the brain and the spinal cord
- controls everything in the body.
The Central Nervous System
WHat does Spinal cord and brain consists of?
a. White matter
b. Grey matter
bundles of axons each coated with a sheath of myelin
White matter
masses of the cell bodies and dendrites each covered with synapses.
Gray matter
Location of each matter in Spinal cord
- White matter at the surface
- Gray matter inside
- conducts sensory information from the peripheral nervous system to the brain
- Conducts motor information
Spinal cord
actions that result from a nerve impulse passing over a reflex arc
- predictable response to a stimulus
Reflex actions
Examples of reflexes
- Knee jerk reflex
- Ankle jerk reflex- Archilles reflex
- Babinski reflex
- Plantar reflex
- Corneal reflex
- Abdominal reflex
extension of lower leg in response to tapping the patellar tendon with a reflex hammer
Knee jerk reflex
Knee jerk reflex are lost in some patients with…
Poliomyelitis and other diseases
extension of foot in response to tapping the Achilles tendon
Ankle jerk reflex-Achilles reflex
extension of great toe in response to stimulation of outer margin of sole of foot
Babinski reflex
plantar flexion of all toes and a slight turning in and flexion of anterior part of foot in response to stimulation of outer edge of sole
Plantar reflex
winking in response to touching cornea
Corneal reflex
drawing in of abdominal wall in response to stroking the side of the abdomen
Abdominal reflex
An organ that controls your emotions, your thoughts, and every movement you make
Brain
By definition, it is three layers of tissue that protect and support the brain and spinal cord
The Meninges
The three layers of tissue that creats the meninges
Dura matter
Arachnoid
Pia Mater
pressed against the bony surface of the interior of the vertebrae and the cranium
Dura mater
The fluid that fills the region between archnoid and pia mater
Cerebrospinal fluid (CSF)
Located between dura mater and pia mater
Arachnoid
the innermost layer of meninges, thin and delicate.
Pia mater
- Produced in the lateral ventricles
– Absorbed by the arachnoid villi
CSF
are specialized “absorbing” filters
Archnoid villi
Parts that support the brain
- Bone
- Meninges
- Cerebrospinal fluid
– Face Attachment
– Holds CSF and Supports Meninges
Bone
– Main brain support
– Suspends, Compartmentalizes, and Coats
Meninges
– In a bony container, allows dissipation of sudden shocks (forces)
Cerebrospinal fluid
Three regions of brain
Forebrain
Midbrain
Hindbrain
Parts of brainstem
- Medulla oblongata
- Midbrain
- Pons
the part of the brain that connects the brainstem to the spinal cord
Medulla oblongata
Functions of medulla oblongata
- Performs sensory, motor, reflex actions
- Contain, cardiac, vasomotor, respiratory centers (vital centers)
- Also contain centers for non-vital reflexes-vomitting, coughing, sneezing, hicuppping, swallowing
Nerve impulses arising here rhythmically stimulate the intercostal muscles and diaphragm. Making…
Breatjing possible
The receptors of neurons that control breathing
Where opiates (like heroin) bind
Mu receptors
- smallest region of the brain that acts as a sort of relay station for auditory and visual information
Midbrain
are involved in the control of body movement
Red nucleus and Substantia nigra
It is associated with parkinson’s disease
Degeneration of neurons in Substantia nigra
- from Latin word meaning “bridge”
- contains the sleep paralysis center of the brain and also plays a role in generating dreams
Pons
Functions of Pons
- Pneumotaxic centers which aid in respiration
- Primarily deal with sleep, swallowing, bladder control, hearing etc
serve as a relay station carrying signals from various parts of the cerebral cortex to the cerebellum.
Pons
*Represents 10% of the weight of the brain, but contains as many neurons as all the rest of the brain combined
Cerebellum
a center for motor skills, posture and maintaining equilibrium
Cerebellum
People with damage to their cerebellum are
- able to contract their muscles, but their motions are jerky and uncoordinated.
Parts of Diencephalon (interbrain)
Thalamus
Hypothalamus
chief sensory integrating center
-expressions of emotions
Thalamus
All sensory input passes through thalamus exept?
Olfaction
regulator/coordinator of autonomic activities
Hypothalamus
Receives vasopressin and oxytocin from the hypothalamus and releases them into the blood.
Posterior lobe of the pituitary
What does damage to hypothalamus cause?
Homeostatis of body temp, blood chemistry etc, goes out of control
The human forebrain
Prosencephalon
The human forebrain (prosencephalon) is made up of a pair of large
Cerebral hemisphere
Functions of cerebral hemisphere
- Sensory functions
- Motor function
- Integrative function
Types of sensory functions by cerebral hemisphere
a. Somatic senses
b. Special senses
Sensory areas of cebral hemisphere
- Primary somatosensory cortex
- Somatosensory association areas
- Visual areas
- Auditory areas
- Olfactory cortex*
- Gustatory cortex
movement of limb muscles
Motor functions
Types of motor functions
a. Primar motor cotex
b. premotor cortex
c. Broca’s area
d. Frontal eye field
a brain region that’s critical for voluntary movement
Primary motor cortex
controls learned motor skills of a repetitive and patterned nature
Premotor cortex
- present usually in left hemisphere only
- directs muscles involved in articulation
Broca’s area
controls voluntary movement of the eye
Frontal eye field
Integrative function of brain hemisphere
a. Consciousness
b. Language
c. Emotions
d. memory
communicate with primary sensory areas and with motor cortex to analyze, recognize and act on sensory inputs
Association areas
anterior portion of - frontal lobes; most complicated region
- involved with intellect, cognition and personality
Pre-frontal area
What does PFA control?
- abstract ideas, judgment, reason, persistence, planning, concern for others and conscience
When did PF lobotomy happened?
cure during 1930s-1950s
what does Lobotomy do to pre-fontal?
severs connections to PFC
what happens when there is a Tumors in PFC-mental/personality disorders?
- wide mood swings
- loss of attentiveness
- inhibitions
- person oblivious to social restraints and careless about personal appearance
gnostic or ‘knowing’
General interpretation area
where is General interpretation area located?
Usually in left hemisphere
what does gnostic do?
- helps understand the situtation and decides on appropriate response
how does gnostic function?
- receives inputs from sensory association areas— integrates all incoming signals into one though or understanding
what happens when there is a injury in gnostic area?
one becomes an imbeclie (one’s ability to interpret situation is lost)
occur in both hemispheres
includes Wenicke’s area
Language areas
involved in sounding out unfamiliar words
Wernicke’s area
involved in non-verbal, emotional components of language ( tone/lilting of voice)
Affective language areas
individual tells you (honestly) he is happy to see you with a flat voice and stony facial expression
Aprosodia
- ‘split-brain concept’
- ‘division of labor’
- Each hemisphere has unique abilities not shared by the other
LATERALIZATION OF CORTICAL FUNCTIONING
*Cerebral dominance for Left
dominant for language, math, logic
*Cerebral dominance for Right
- Visual/spatial skills
- intuition
- emotion
- appreciation of art and music
are generally left-handed and more often male
right dominant people
____ of individuals with left-cerebral dominance are ______
90%
right-handed
___roles of hemispheres are reversed or they share functions___
10%
equally
Results of cerebral confusion and learning disabilities
- Ambidexterity
- Dyslexia
mutuality of brain control
Ambidexterity
-due to lack of cerebral dominance
- people reverse order of letters or syllables in words or words in sentences
Dyslexia
Disorders of the CNS
- Hydrocephalus
- Epilepsy
- Multiple sclerosis
- Alzheimer’s disease
- Adrenoleukodystrophy
- CVA (cerebrovascular accident)
- Celebral Palsy
obstruction in drainage of csf cure- shunt(tube) to drain excess fluid
Hydrocephalus
- characterized by seizures
- sudden abnormal bursts of neuron activity that result in temporary changes in brain function
Epilepsy
Epilepsy is controlled by _____ which block neurotransmitters in affected areas of brain
anticonvulsive drugs
what does epilepsy do to jaw muscles?
Causes strong contractions
nervous tissue is replaced by connective tissue which results in hardened patches everywhere
Multiple sclerosis
degenerative disease; plaque formation in synaptic vesicles
Alzheimer’s Disease
How is Alzheimer’s disease characterized?
- By extreme forgetfulness
- Mood swings
- Dementia
- Fatal
- Hereditary
- corrosion of myelin sheath; sex-linked
- sensory-neural disorder;irreparable damage
Adrenoleukodystrophy
What kind of inheritance is Adrenoleukodystrophy
X-linked diease (Affects male)
- results in destruction of neurons of the motor area of cerebrum due to hemorrhage or cessation of blood flow through cerebral blood vessels
Cerebrovascular accident
- permanent damage to motor areas of brain which remains throughout life
Cerebral pasly
Possible causes of cerebral palsy
- Mechanical trauma
- Nerve-damaging poisons
- prenatal infections of mother
- reduced oxygen supply to brain due to difficult delivery