3 - Cellular Respiration Flashcards
4 Metabolic stages of cellular respiration
- Glycolysis
- Pyruvate oxidation
- Krebs Cycle
- Electron Transport Chain
– respiration without O2
– in cytosol
- splitting of sugar
Glycolysis
Cellular respiration
- Step-by-step breakdown of high-energy glucose molecules to release energy
- occurs in stages controlled by enzyme
– respiration using O2
– in mitochondria
Aerobic respiration
- migration from cytosol to matrix
Grooming cycle
Location where krebs cycle happens
Mitochondrial matrix
Krebs cycle other name
Citric acid cyle
Location where ETC happen
inner mitochonndrial membrane
Energy Currency of Cells
ATP
- ATP is constantly recycles in our cells
- A working muscle cell recycle all ATP molecules about once per Minute.
ATP-ADP cycle
Different types of Cellular respiration
- Aerobic respiration
- Anaerobic respiration
releases carbon dioxide and water as waste products.
Aerobic respiration
What happens to glucose in anerobic respiration
incompletely broken down
ATP product of glycolysis
2 atp for every one glucose
2 phases of glycolysis
- energy investing
- energy generating/harvest
- Glucose “priming”
- Get glucose ready to split
energy investing
NADH and ATP production in glycolysis
Energy generating/harvesting
Glycolysis produces:
4 atp and 2 NADH
Glycolysis consumes:
2 ATP
Glycolysis net:
2 ATP and 2 NADH
First cells had no organelles
Prokaryotes
Prokaryotes that evolve ____ are ____ of all modern life
- glycolysis
- ancestors
2 types of anaerobic fermentation
- Alcohol fermentation
- Lactic acid fermentation
Dead end process
- At approx 12% ethanol, kills yeast. Can’t reverse the reaction
Alcohol fermentation
- Reversible process
- Once O2 is available lactate is converted back to pyruvate by the liver
Lactic Acid Fermentation
Pyruvate branching point
No oxygen=fermentation
With oxygen=krebs cycle (mitochondria)
Pyruvate enters mitochondria
- produces Acetyl CoA
Oxidation of pyruvate
Oxidation of Pyruvate equation
Pyruvate + NAD+ + CoA -> Acetyl CoA + NADH and CO2
What happens to acetyl CoA after oxidation of pyruvate
- Enters the Kreb Cycle
Aka Citric Acid Cycle, happens in mitochondria matrix
Krebs cycle
Who introduced krebs cycle
Hans Krebs (1900-81)
Products of krebs cycle
- 8 NADH
- 2 ATP
- 2 FADHs
bacteria -> 3.5 billion years ago (___)
Glycolysis
free O2 -> 2.7 billion years ago (___)
Photosynthesis
- series of molecules built into mitochondrial membrane (along the cristae)
Electron Transport Chain
How much ATP does ETC yield from 1 glucose?
- approx. 34 ATP
what “pulls” the electrons down the ETC?
Oxidative phosphorylation
The diffusion of ions across a membrane
Chemiosmosis
What does chemiosmosis create?
Create ATP
enzyme used during chemiosmosis
ATP synthase
Proposed chemiosmotic hypothesis
Peter Mitchell