2a- Cell membrane structure Flashcards

1
Q

Gateway to the Cell
* Acts as a boundary
* Controls what enters and leaves cell
* Regulates chemical composition
* Maintains homeostasis

A

Cell membrane

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2
Q

The cell membrane
is ____ and allows a
____ ____ to
move

A
  • flexible
  • unicellular organism
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3
Q

Biological membranes consist of

A

Lipid bilayers

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4
Q

Plasma membrane models

A
  • Sandwich model
  • Unit membrane
  • Fluid Mosaic Model
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5
Q

Proposed sandwich model

A

Danielli + Davson

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6
Q

2 layers of globular proteins with phospholipid inside to make a layer and then join 2 layers together to make a channel for molecules to pass

A

Sandwich model

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7
Q

Outer layer of protein with phospholipid bilayer inside, -believed all cells same composition

A

Unit membrane model

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8
Q

Phospholipid bilayer with proteins partially or fully imbedded, electron micrographs of freeze fractured membran

A

Fluid Mosaic Model

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9
Q

The lipids in a membrane are organized into a
___ ___ ___

A

liquid crystalline lattice

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10
Q

The lattice becomes a ____ ____ gel at the transition temperature

A

frozen crystalline

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11
Q

Importance of two layers of lipids in plasma membrane?

A

at least a portion of
the membrane repels the water that constantly surrounds it. Too much water could burst the cell

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12
Q

plasma membrane has consistency of olive oil at body temperature, due to unsaturated phospholipids.

A

Fluid

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13
Q

proteins form a collage that differs on either side of membrane and from cell to cell (greater than 50 types of proteins)

A

Mosaic

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14
Q

Facing out

A

Hyrophilic portions

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15
Q

facing in

A

Hydrophobic portions

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16
Q

Low temperature

A

Gel phase, hydrocarbons are tightly packes

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17
Q

moves to fluid phase

A

At high temp., bilayer ‘melts’, movement is allowed

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18
Q

Types of phospholipids movement

A
  1. Flip-flop
  2. Lateral
  3. Flexion
  4. Rotation
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19
Q

The proteins move laterally within the cell membrane

A

Lateral diffusion

20
Q

While the lipids can move both laterally and rotate 360 degrees

A

Flip-flop diffusion

21
Q

Cholesterol affects fluidity

A

Lessens fluidity (body temp)
Maintains fluidity (Colder temp)

22
Q

Classifications of membrane proteins

A
  • Peripheral membrane proteins
  • Integral membrane proteins
  • Transmembrane proteins
23
Q

are proteins that dissociate from the membrane following treatments with polar reagents that do not disrupt the phospholipid bilayer.

A

Peripheral membrane proteins

24
Q

can be released only by
treatments that disrupt the phospholipid bilayer

A

Integral membrane proteins

25
Q

span the lipid bilayer with portions exposed on both sides of the membrane.

A

Transmembrane proteins

26
Q

Types of membrane proteins

A
  • Transport proteins
  • Receptor proteins
  • Enzymatic proteins
  • Cell recognition proteins
  • Attachment proteins
  • Intercellular junction proteins
27
Q

Types of transport proteins

A
  • Channel proteins
  • Carrier proteins
28
Q

channel for lipid insoluble molecules and ions to pass freely through

A

Channel proteins

29
Q

bind to a substance and
carry it across membrane, change
shape in process

A

Carrier proteins

30
Q

Bind to chemical messengers, which sends a message into the cell causing cellular reaction

A

Receptor proteins

31
Q

Carry out enzymatic reactions right at the membrane when a substrate binds to the active site

A

Enzymatic proteins

32
Q

Glycoproteins (and
glycolipids) on extracellular surface
serve as ID tags

A

Cell recognition proteins

33
Q

Attach to cytoskeleton and or extracellular matrix

A

Attachment proteins

34
Q

protein fibers and carbohydrates secreted by cells and fills the spaces between cells and supports cells in a tissue

A

Extracellular matrix

35
Q

connect to both

A

Integrins

36
Q

can influence activity inside the cell and coordinate the behavior of all the cells in a tissue

A

Extracellular matrix

37
Q

Bind cells together

A

Intercellular junction proteins

38
Q

Types of cell junctions

A
  • Tight junctions
  • Desmosomes
  • Gap junctions
39
Q

Transmembrane Proteins of opposite cells attach in a tight zipper-like fashion
- No leakage

A

Tight junctions

40
Q

Example of tight junctions

A
  • Intestine
  • Kidneys
  • Epithelium of skin
41
Q

Cytoplasmic plaques of two cells bind with the aid of intermediate filaments of keratin
* Allows for stretching

A

Desmosomes

42
Q

Example of Desmosomes

A

Stomach
Bladder
Heart

43
Q
  • Channel proteins of opposite cells join together providing channels for ions, sugars, amino acids, and other small molecules to pass.
  • Allows communication between cells
A
  • Gap Junctions
44
Q

Can Establish the Rate of Membrane Component Movement

A

FRAP (Flourescence Recovery After Photobleaching

45
Q

is not found in plant
membranes

A

Cholesterol