Examples of Autocrine and Paracrine Regulators Flashcards

1
Q

Somatomedins major sites of production

A

Man organs, particularly liver and cartilages

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1
Q

Insulin-like growt factors

A

Somatomedins

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2
Q

Somatomedins; Major actions

A

Growth and cell division

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3
Q

Nitric oxide ; Major sites of production

A

Endothelium of blood vessels; neurons; macrophages

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4
Q

Nitric oxide ; Major actions

A

Dilation of blood vessels; neural messenger, antibacterial agent

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5
Q

Endothelins; Major sites of production

A

Endothelium of blood vessels; other organs

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6
Q

Platelet-derived growth factor ; Major sites of production

A

Platelets; macrophages; vascular smooth muscle cells

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7
Q

Epidermal growth factors ; Major sites of production

A

Epidermal tissues

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8
Q

Neurotrophins; Major sites of production

A

Schwann cells; neurons

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9
Q

Bradykinin; Major sites of production

A

Endothelium of blood vessels

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10
Q

Interleukins (cytokines); Major sites of production

A

Macrophages; lymphocytes

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11
Q

Prostaglandins; Major sites of production

A

Many tissues

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12
Q

TNFa

A

Tumor necrosis factor alpha

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13
Q

TNFa; Major sites of production

A

Macrophages; adipocytes

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14
Q

Endothelins; major actions

A

Constriction of blood vessels; other effects

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15
Q

Platelet-derived growth factors ; major actions

A

Cell division within blood vessels

16
Q

Epidermal growth factors; major actions

A

Cell division in wound healing

17
Q

Neurotrophins; major actions

A

regenration of preipheral nerves

18
Q

Bradykinin; major actions

A

Dilation of blood vessels

19
Q

Interleukins; major actions

A

regulation of immune system

20
Q

Prostaglandins; major actions

A

Wide variety

21
Q

TNFa; major actions

A

Wide variety