NEISSERIA Flashcards

1
Q

What kind of pathogen is Neisseria?

A

Bacteria

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2
Q

Is Neisseria gram positive or gram negative?

A

Gram negative

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3
Q

What would Neisseria look like on a microscope slide?

A

Pink diplococcus (pairs of spheres)

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4
Q

Is Neisseria aerobic or anaerobic?

A

Aerobic (O2)

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5
Q

What are some strains of Neisseria?

A

-Neiserria meningitis
-Neisseria gonorrhea

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6
Q

What is the epidemiology/distribution of N.meningitis?

A

Sporadic or endemic outbreaks in communities
-Common in part of Africa (Meningitis belt: belt/horizontal line across map of northern Africa where this most commonly occurs)

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7
Q

Who is at greater risk for contracting N. meningitis?

A

Those without a spleen (asplenia), Complement immunodeficient people (such as Lupus)

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8
Q

How would an N. meningitis infection present?

A

-Acute bacterial meningitis (inflammation of brain/spinal cord)
-bacteremia, sepsis

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9
Q

How can an N. meningitis infection be treated?

A

VACCINATION! prevention

-Phrophylactic (preventative) treatment for patients who may be at risk

-Droplet precautions (masks, PPE, etc.)

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10
Q

What does N. gonorrhea cause?

A

Gonorrhea
*second most common STI

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11
Q

How is N. gonorrhea transmitted?

A

Sexually

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12
Q

How would an N. gonorrhea infection present in men?

A

-Pus discharge
-Bleeding
-Painful urination
-Burning
-Urethritis (inflammation of urethra)
-Pharyngitis
-Conjunctivitis

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13
Q

How would an N. gonorrhea infection present in women?

A

-Vaginal bleeding/discharge
-Pelvic pain
-Painful urination
-Pharyngitis
-Conjunctivitis
-Hepatic inflammation (Fitz-Hugh Curtis Syndrome), generally not seen in men

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14
Q

Can an N. gonorrhea infection spread to other parts of the body?

A

Although it is uncommon, the infection may spread from the genitourinary tract to joints and blood (bacteremia)

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15
Q

How can we test for an N. gonnorhea infection?

A

-Dirty urine sample (in men)
-Blood culture
-Rectal swab
-Throat swab
-Cervical swab (in women)

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16
Q

How can an N. gonorrhea infection be treated?

A

Genitourinary:
-Ceftriaxone + Azithromycin
-Gentamycin + Azithromycin

Severe widespread:
-Ceftriaxone (IV) + Azithromycin for weeks depending on site of infection

***Fluoroquinolones no longer recommended due to resistance