Naloxone (Narcan)

Question 1

Narcan classification

Answer 1

Narcotic antagonist

Question 2

Narcan action

Answer 2

1. Binds to opiate receptor sites
2. May precipitate withdrawal symptoms
3. Reverse respiratory depression secondary to narcotic OD

Question 3

Narcan onset and duration

Answer 3

1. IV/IO/ET 1-2 min, IN 3-4 min, 2-5 min IM

2. Variable

Question 4

Narcan indication

Answer 4

1. Respiratory depression secondary to suspected narcotic ingestion
2. Treatment of coma of unknown origin with apnea/hypoventilation or in neonatal resuscitation

Question 5

Narcan contraindication

Answer 5

Hypersensitivity

Question 6

Narcan precautions

Answer 6

1. May precipitate withdrawal symptoms

2. Prepared to restrain violent patients

Question 7

Narcan dosage and administration

Answer 7

Adult:
1. .4-2mg IV/IO/IN/IM/ET repeated every 2-3 min up to 10mg until pt begins to breath
2. If no response after 10mg consider different etiology of respiratory depression
Pediatric:
1. 0.1mg/kg IN/IV/IM/IO/ET up to 2mg until pt begins to breath. May repeat as needed not to exceed 10mg

Question 8

Narcan adverse reaction

Answer 8

Withdrawal symptoms:

Sweating, tremor, N/V, agitation belligerence, hyper/hypoventilation

Question 9

Narcan reference in protocol

Answer 9

Respiratory (Difficulty Breathing)
Medical (ALOC)
OB/GYN (Neonatal Resuscitation)