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HAEMATOLOGY > [myeloproliferative] > Flashcards

[myeloproliferative] Flashcards

1
Q
A

RBCs
Platelets
Fibroblasts
WBCs

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2
Q
A

polycythaemia vera

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3
Q
A

essential thrombocythaemia

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4
Q
A

CML

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5
Q
A

myelofibrosis

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6
Q
A

relative (normal RBC mass, low plasma)

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7
Q
A

polycythaemia rubra vera

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8
Q
A

Hypoxia (e.g. altitude)

inappropriate EPO secretion

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9
Q
A

JAK2

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10
Q
A

platelets

WBCs

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11
Q
A

hyperviscosity

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12
Q
A

fingers
toes
(aka erythromyalgia)

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13
Q
A

hot temperatures

“after hot bath”

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14
Q
A

increased RBC turn over therefore release of yrate

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15
Q
A

thrombus

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16
Q
A

CML

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17
Q
A

polycythaemia rubra vera
myelofibrosis
essential thrombocytopaenia

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18
Q
19
Q
A

hypercellularity

erythroid hyperplasia

20
Q
A

Radioactive chromium-51 - shows RBC mass

21
Q
A

normal O2 partial pressure

raised red cell mass on chromium-51 Ix

23
Q
A

venesection

24
Q
A

hydroxycarbamide

26
Q
A

thrombosis

27
Q
28
Q
A

alpha interferon

29
Q
A

aspirin 75mg daily

30
Q
A

every 3 months

32
Q
A

bleeding

thrombosis

33
Q
A

abnormal platelet function

34
Q
A

aspirin 75mg/day
+
Hydroxycarbamide (if >60 or previous thrombosis)

35
Q
A

> 60
or
previous thrombosis

36
Q
A

headache
chest pain
light headedness

37
Q
A

release of PDGF (platelet derived growth factor)

38
Q
A

massive splenomegaly

39
Q
A

abdominal discomfort

40
Q
A

teardrop RBCs

41
Q
A

abdominal discomfort
night sweats
wt loss

42
Q
A

marrow support

43
Q
A

neutrophil support (regimens = sterile)
RBC transfusion
Platelets transfusion

HAEMATOLOGY (25 decks)

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