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HAEMATOLOGY > [anticoagulants] > Flashcards

[anticoagulants] Flashcards

1
Q
A

LMWH

unfractionated

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2
Q
A

SC

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3
Q
A

Factor Xa

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4
Q
A

LMWH

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5
Q
A

LMWH

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6
Q
A

-parin

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7
Q
A

dalteparin

enoxeparin

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8
Q
A

binds to antithrombin 3 and potentiates it

AT3 inhibits thrombin, Xa and IXa

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9
Q
A

rapid

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10
Q
A

LMWH

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11
Q
A

HIT

heparin induced thrombocytopenia

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12
Q
A 
previous HIT
bleeding disorders
peptic ulcer
cerebral haemorrhage
severe hypertension
neurosurgery
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13
Q
A

PO

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14
Q
A

inhibits reductase enzyme responsible for activating vit K

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15
Q
A

YES

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16
Q
A

warfarin

17
Q
A

Xa inhibitor

18
Q
A

LMWH

Fondaparinux

19
Q
A

5 days
OR
until INR reached

(whichever is longer)

20
Q
A

warfarin has an initial prothrombotic effect

21
Q
A

6 weeks below knee

3 months above knee

22
Q
A

unprovoked DVT

i.e. no surgery/immobility

23
Q
A

1.5 - 2.5

24
Q
A

LMWH given for 6 months

25
Q
A

2 - 3

26
Q
A

3.5

27
Q
A

3-4

28
Q
A

enduring cases e.g. thombophilia

29
Q
A

> 5

30
Q
A

prothrombin complex
Vit K IV

(FFP if vit k too slow)

31
Q
A

10mg

32
Q
A

5mg (if >60, cardiac, liver disease)

10mg

33
Q
A

protamine sulphate

34
Q
A

binds to heparin and inactivates it

HAEMATOLOGY (25 decks)

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