[anticoagulants] Flashcards
1
Q
A
LMWH
unfractionated
2
Q
A
SC
3
Q
A
Factor Xa
4
Q
A
LMWH
5
Q
A
LMWH
6
Q
A
-parin
7
Q
A
dalteparin
enoxeparin
8
Q
A
binds to antithrombin 3 and potentiates it
AT3 inhibits thrombin, Xa and IXa
9
Q
A
rapid
10
Q
A
LMWH
11
Q
A
HIT
heparin induced thrombocytopenia
12
Q
A
previous HIT bleeding disorders peptic ulcer cerebral haemorrhage severe hypertension neurosurgery
13
Q
A
PO
14
Q
A
inhibits reductase enzyme responsible for activating vit K
15
Q
A
YES
16
Q
A
warfarin
17
Q
A
Xa inhibitor
18
Q
A
LMWH
Fondaparinux
19
Q
A
5 days
OR
until INR reached
(whichever is longer)
20
Q
A
warfarin has an initial prothrombotic effect
21
Q
A
6 weeks below knee
3 months above knee
22
Q
A
unprovoked DVT
i.e. no surgery/immobility
23
Q
A
1.5 - 2.5
24
Q
A
LMWH given for 6 months
25
Q
A
2 - 3
26
Q
A
3.5
27
Q
A
3-4
28
Q
A
enduring cases e.g. thombophilia
29
Q
A
> 5
30
Q
A
prothrombin complex
Vit K IV
(FFP if vit k too slow)
31
Q
A
10mg
32
Q
A
5mg (if >60, cardiac, liver disease)
10mg
33
Q
A
protamine sulphate
34
Q
A
binds to heparin and inactivates it
